Antibiograms from community-acquired uropathogens in Gulu, northern Uganda - a cross-sectional study

BMC Infectious Diseases

Volumn 13, Issue 1, 2013, Pages

  Odongo, Charles O ^a   Anywar, Denis A ^a   Luryamamoi, Kenneth ^a   Odongo, Pancras ^a  

^a GULU UNIVERSITY   (Uganda)

Author keywords

Antibiograms; Antibiotic resistance; Empirical treatment; Uganda; Uropathogens

Indexed keywords

AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; AZITHROMYCIN; CEFALEXIN; CIPROFLOXACIN; COTRIMOXAZOLE; GENTAMICIN; LEVOFLOXACIN; NALIDIXIC ACID; NITROFURANTOIN; OXACILLIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; COMMUNICABLE DISEASE; CROSS-SECTIONAL STUDY; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; KLEBSIELLA; NONHUMAN; PROTEUS MIRABILIS; STAPHYLOCOCCUS; UGANDA; URINARY TRACT INFECTION; URINE CULTURE;

ADOLESCENT; ADULT; AGED; AMOXICILLIN-POTASSIUM CLAVULANATE COMBINATION; ANTI-BACTERIAL AGENTS; BACTERIA; COMMUNITY-ACQUIRED INFECTIONS; CROSS-SECTIONAL STUDIES; DRUG RESISTANCE, BACTERIAL; FEMALE; GENTAMICINS; HUMANS; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; PREGNANCY; UGANDA; URINARY TRACT INFECTIONS; YOUNG ADULT;

EID: 84876801919     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-13-193     Document Type: Article

References (40)

1. Hummers-Pradier E, Kochen MM. Urinary tract infections in adult general practice patients. Brit J Gen Pract 2002, 52:752-761.
2. McLaughlin SP, Carson CC. Urinary tract infections in women. Med Clin North Am 2004, 88:417-429. 10.1016/S0025-7125(03)00148-2, 15049585.
3. Yamamoto S, Tsukamoto T, Terai A, Kurazono H, Takeda Y, Yoshida O. Genetic evidence supporting the fecal-perineal-urethral hypothesis in cystitis caused by Escherichia coli. J Urol 1997, 157:1127-1129. 10.1016/S0022-5347(01)65154-1, 9072556.
4. Miller LG, Tang AW. Treatment of uncomplicated urinary tract infections in an era of increasing antibiotic resistance; a concise review for clinicians. Mayo Clin Proc 2004, 79:1048-1054. 10.4065/79.8.1048, 15301333.
5. WHO Community-Based Surveillance of Antimicrobial Use and Resistance in Resource-Constrained Settings; report on five pilot projects 2009, 20 Apia Avenue, 1211 Geneva, Switzerland: WHO Press, WHO.
6. Gupta K, Hooten TM, Stamm WE. Increasing antimicrobial resistance and the management of uncomplicated community-acquired urinary tract infections. Ann Int Med 2001, 135:41-50. 10.7326/0003-4819-135-1-200107030-00012, 11434731.
7. Sahm DF, Thornsberry C, Mayfield DC, Jones ME, Karlowsky JA. Multidrug resistant isolate of E. coli: prevalence and patient demographics in the United States in 2000. Antimicrob Agents Chemother 2001, 45:1402-1406. 10.1128/AAC.45.5.1402-1406.2001, 90480, 11302802.
8. Karlowsky JA, Kelly LJ, Thornsberry C, Jones ME, Sahm DF. Trends in antimicrobial resistance among urinary tract isolates of Escherichia coli from female outpatients in the United States. Antimicrob Agents Chemother 2002, 46:2540-2545. 10.1128/AAC.46.8.2540-2545.2002, 127340, 12121930.
9. Andrade SS, Sader HS, Jones RN, Pareira AS, Pignatari ACC, Gales AC. Increased resistance to first-line agents among bacterial pathogens isolated from urinary tract infections in Latin America: time for local guidelines?. Mem Inst Oswaldo Cruz 2006, 101:741-748.
10. Kurutepe S, Surucuoglu S, Sezgin C, Gazi H, Gulay M, Ozbakkaloglu B. Increasing antimicrobial resistance in Escherichia coli isolates from community acquired urinary tract infections during 1998-2003 in Manisa, Turkey. Japan J Infect Dis 2005, 58:159-161.
11. Shigemura K, Tanaka K, Adachi M, Yamshita M, Arakawa S, Fujisawa M. Chronological change of antibiotic use and antibiotic resistance in Escherichia coli causing urinary tract infections. J Infect Dis Chemother 2011, 17(5):646-651.
12. Obaskei-Ebor EE. Trimethoprim/Sulfamethoxazole resistance in E. coli and Klebsiella species of urinary isolates. Afr J Med Sci 1988, 17:175-180.
13. Mordi RM, Erah PO. Susceptibility of common urinary isolates to the commonly used antibiotics in a tertiary hospital in southern Nigeria. Afr J Biotech 2006, 5:1067-1071.
14. Kyabagu D, Ejobi F, Olila D. The sensitivity to first-line antibiotic therapy of the common urinary tract bacterial infections detected in urine samples at a hospital in metropolitan Kampala (Uganda). Afr Health Sci 2007, 7:214-222. 3074367, 21499486.
15. Dada-Adegbola HO, Muili KA. Antibiotic susceptibility pattern of urinary tract pathogens in Ibadan, Nigeria. Afr J Med Sci 2010, 39:173-179.
16. Schito GC, Naber KG, Botto H, Palou J, Mazzei T, Gualco L. The ARSEC study: an international survey on the antimicrobial resistance of pathogens involved in uncomplicated urinary tract infections. Int J Antimicrob Agents 2009, 34(5):407-413. 10.1016/j.ijantimicag.2009.04.012, 19505803.
17. De Backer D, Christiaens T, Heytens S, De Sutter A, Stobberingh EE, Verschraegen G. Evolution of Bacterial susceptibility pattern of Escherichia coli in uncomplicated urinary tract infections in a country with high antibiotic consumption: a comparison of two surveys with a 10 year interval. J Antimicrob Chemother 2008, 62(2):364-368. 10.1093/jac/dkn197, 18499768.
18. Okeke IN, Laxminarayan R, Bhutta ZA, Duse AG, Jenkins P, O'Brien TF, Mendez PA, Klugman KP. Antimicrobial resistance in developing countries. Part I: recent trends and current status. Lancet Infect Dis 2005, 5(8):481-493. 10.1016/S1473-3099(05)70189-4, 16048717.
19. Gupta K. Addressing antibiotic resistance. Dis Mon 2003, 49:99-110. 10.1016/S0011-5029(03)90003-4, 12601340.
20. Ministry of Health and The Uganda National Drug Authority Uganda Clinical Guidelines 2010. National Guidelines on Management of Common Disease Conditions 2010, Kisubi, Uganda: Marianum Press Ltd, Ministry of Health and The Uganda National Drug Authority.
21. Kirby WM, Bauer AW. Antibiotic susceptibility testing by a standardized single disk method. Am J Clin Path 1966, 45:493-496.
22. Thomson RB, Miller JM. Specimen collection, transport, and processing: bacteriology. Manual of Clinical Microbiology 2003, Washington DC: American Society of Microbiology, Murray PR, Baron EJ, Jorgensen JH, Pfaller MA, Yolken RH, 8.
23. Strandberg K, Beermann B, Lonnerholm G. Diagnosis and Treatment of Urinary Tract Infections: recommendations from the expert group 1990, Medical Products Agency: Uppsala, Sweden.
24. Cheesbrough M. District Laboratory Practice in Tropical Countries. Part 2. Microbiology 2000, Doddington: Cambridge University Press.
25. Clinical Laboratory Standards Institute Performance Standards for Antimicrobial disk susceptibility tests; Approved Standard 9th Edition. Document M2-A9 2006, Wayne, PA: CLSI, 26: 1, Clinical Laboratory Standards Institute.
26. Mwaka AD, Mayanja-Kizza H, Kigonya E, Kaddu-Mulindwa D. Bacteriuria among adult non-pregnant women attending Mulago hospital assessment center in Uganda. Afr Health Sci 2011, 11:182-189. 3158526, 21857848.
27. Andabati G, Byamugisha J. Microbial etiology and sensitivity of asymptomatic bacteriuria among ante-natal mothers in Mulago hospital, Uganda. Afr Health Sci 2010, 10:349-352. 3052809, 21416036.
28. Okeke IN, Adebayo L, Edelman R. Socioeconomic and behavioral factors leading to acquired bacterial resistance to antibiotics in developing countries. Emerg Infect Dis 1999, 5(1):18-27. 10.3201/eid0501.990103, 2627681, 10081668.
29. Kunin CM, Johansen KS, Worning AM, Daschner FD. Report on a symposium on use and abuse of antibiotics worldwide. Rev Infect Dis 1990, 12:12-19. 10.1093/clinids/12.1.12, 2405465.
30. Ouma F. Uganda: Self-medication causing drug resistance. 2007, 17. Uganda: New Vision Printing and Publishing Coporation, Kaija B, Kakande J, The New Vision Newspaper, May 29, 2007.
31. Kyalimpa J. Health-Uganda: self-medication blamed for increased drug resistance. In: Inter Press Service News Agency, July 15 2011 http://www.ipsnews.net/2011/07/health-uganda-self-medication-blamed-for-increased-drug-resistance. Accessed on November 22nd 2011.
32. Stamm WE, Norrby SR. Urinary tract infections: disease panorama and challenges. J Infect Dis 2001, 183(1):1-4. 10.1086/317653, 11106535.
33. Patel RB, Welling PG. Clinical pharmacokinetics of cotrimoxazole (sulfamethoxazole-trimethoprim). Clin Pharmacokin 1980, 5:405-423.
34. Warren JW, Abrutyn E, Hebel JR, Johnson RJ, Schaeffer AJ, Stamm WE. Guidelines for antimicrobial treatment of uncomplicated acute bacterial cystitis and acute pyelonephritis in women. Clin Infect Dis 1999, 29:745-758. 10.1086/520427, 10589881.
35. Naber KG, Bergman B, Bishop MC, Bjerklund-Johansen TE, Botto H, Lobel B. EAU guidelines for the management of urinary and male genital tract infections. Urinary Tract Infection (UTI) Working Group of the Health Care Office (HCO) of the European Association of Urology (EAU). Eur Urol 2001, 40(5):576-588. 10.1159/000049840, 11752870.
36. Prins JM, Buller HR, Kuijper EJ, Tange RA, Speelman P. Once versus thrice daily gentamicin in patients with serious infections. Lancet 1993, 341:335-339. 10.1016/0140-6736(93)90137-6, 8094114.
37. Rupp ME, Soper DE, Archer GL. Colonization of the female genital tract with Staphylococcus saprophyticus. J Clin Microb 1992, 30(11):2975-2979.
38. Jordan PA, Iravani A, Richard GA, Baer H. Urinary tract infection caused by Staphylococcus saprophyticus. J Infec Dis 1980, 142(4):510-515.
39. Uganda total fertility rate: total fertility rank chart http://www.indexmundi.com/uganda/total_fertility_rate.html. Accessed on 19th February 2013.
40. Schmiemann G, Gagyor I, Hummer-Pradier E, Bleidorn J. Resistance profiles of urinary tract infections in general practice - an observational study. BMC Urol 2012, 12:33. 10.1186/1471-2490-12-33, 3534546, 23171154.