Exhaled nitric oxide decreases during exercise in non-asthmatic children

Clinical Respiratory Journal

Volumn 7, Issue 2, 2013, Pages 121-127

  Evjenth, Bjørg ^a   Hansen, Tonje E ^a   Holt, Jan ^a,b  

^a NORDLAND HOSPITAL   (Norway)

^b UNIVERSITY OF TROMSØ   (Norway)

Author keywords

Exercise test; Exhaled nitric oxide in children

Indexed keywords

NITRIC OXIDE;

ADOLESCENT; ARTICLE; BRONCHOSPASM; CHEMILUMINESCENCE ANALYZER; CHILD; CONTROLLED STUDY; EXERCISE TEST; EXPIRED AIR; FEMALE; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; HUMAN; LUNG FUNCTION TEST; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RESPIROMETRY; RHINOCONJUNCTIVITIS; SCHOOL CHILD; SPIROMETER; TREADMILL EXERCISE; ASTHMA; BREATH ANALYSIS; CASE CONTROL STUDY; EXERCISE; EXERCISE INDUCED ASTHMA; EXHALATION; METABOLISM; PHYSIOLOGY; PROCEDURES;

ADOLESCENT; ASTHMA; ASTHMA, EXERCISE-INDUCED; BREATH TESTS; CASE-CONTROL STUDIES; CHILD; EXERCISE; EXHALATION; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; MALE; NITRIC OXIDE;

EID: 84876795169     PISSN: 17526981     EISSN: 1752699X     Source Type: Journal    
DOI: 10.1111/j.1752-699X.2012.00292.x     Document Type: Article

References (30)

1. Ricciardolo FL, Sterk PJ, Gaston B, Folkerts G. Nitric oxide in health and disease of the respiratory system. Physiol Rev 2004;84(3): 731-65.
2. Strunk RC, Szefler SJ, Phillips BR, etal. Relationship of exhaled nitric oxide to clinical and inflammatory markers of persistent asthma in children. J Allergy Clin Immunol 2003;112(5): 883-92.
3. Bacharier LB, Boner A, Carlsen KH, etal. Diagnosis and treatment of asthma in childhood: a PRACTALL consensus report. Allergy 2008;63(1): 5-34.
4. Buchvald F, Baraldi E, Carraro S, Gaston B, De Jongste J, Pijnenburg MW, Silkoff PE, Bisgaard H. Measurements of exhaled nitric oxide in healthy subjects age 4 to 17 years. J Allergy Clin Immunol 2005;115(6): 1130-6.
5. Sachs-Olsen C, Lødrup Carlsen KC, Mowinckel P, Håland G, Devulapalli CS, Munthe-Kaas MC, Carlsen KH. Diagnostic value of exhaled nitric oxide in childhood asthma and allergy. Pediatr Allergy Immunol 2010;21(1 Pt 2): 213-21.
6. Proud D. Nitric oxide and the common cold. Curr Opin Allergy Clin Immunol 2005;5(1): 37-42.
7. American Thoracic Society, European Respiratory Society. ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide, 2005. Am J Respir Crit Care Med 2005;171(8): 912-30.
8. Abuzayan I, Paraskavi U, Turner SW. Changes to exhaled nitric oxide in asthmatic children after drinking a caffeine-containing cola drink. Pediatr Pulmonol 2010;45(12): 1228-32.
9. Laoudi Y, Nikasinovic L, Sahraoui F, Grimfeld A, Momas I, Just J. Passive smoking is a major determinant of exhaled nitric oxide levels in allergic asthmatic children. Allergy 2010;65(4): 491-7.
10. Buchvald F, Hermansen MN, Nielsen KG, Bisgaard H. Exhaled nitric oxide predicts exercise-induced bronchoconstriction in asthmatic school children. Chest 2005;128(4): 1964-7.
11. Malmberg LP, Pelkonen AS, Mattila PS, Hammarén-Malmi S, Mäkelä MJ. Exhaled nitric oxide and exercise-induced bronchoconstriction in young wheezy children - interactions with atopy. Pediatr Allergy Immunol 2009;20(7): 673-8.
12. Silkoff PE, Wakita S, Chatkin J, Ansarin K, Gutierrez C, Caramori M, McClean P, Slutsky AS, Zamel N, Chapman KR. Exhaled nitric oxide after beta2-agonist inhalation and spirometry in asthma. Am J Respir Crit Care Med 1999;159(3): 940-4.
13. Barreto M, Villa MP, Montesano M, Rennerova Z, Monti F, Darder MT, Martella S, Ronchetti R. Reduced exhaled nitric oxide in children after testing of maximal expiratory pressures. Pediatr Pulmonol 2006;41(2): 141-5.
14. Shin HW, Schwindt CD, Aledia AS, Rose-Gottron CM, Larson JK, Newcomb RL, Cooper DM, George SC. Exercise-induced bronchoconstriction alters airway nitric oxide exchange in a pattern distinct from spirometry. Am J Physiol Regul Integr Comp Physiol 2006;291(6): 1741-8.
15. Sheel AW, Road J, McKenzie DC. Exhaled nitric oxide during exercise. Sports Med 1999;28(2): 83-90.
16. Scollo M, Zanconato S, Ongaro R, Zaramella C, Zacchello F, Baraldi E. Exhaled nitric oxide and exercise-induced bronchoconstriction in asthmatic children. Am J Respir Crit Care Med 2000;161(3 Pt 1): 1047-50.
17. Terada A, Fujisawa T, Togashi K, Miyazaki T, Katsumata H, Atsuta J, Iguchi K, Kamiya H, Togari H. Exhaled nitric oxide decreases during exercise-induced bronchoconstriction in children with asthma. Am J Respir Crit Care Med 2001;164(10 Pt 1): 1879-84.
18. Gabriele C, Pijnenburg MW, Monti F, Hop W, Bakker ME, de Jongste JC. The effect of spirometry and exercise on exhaled nitric oxide in asthmatic children. Pediatr Allergy Immunol 2005;16(3): 243-7.
19. Crapo RO, Casaburi R, Coates AL, etal. Guidelines for methacholine and exercise challenge testing 1999. Am J Respir Crit Care Med 2000;161(1): 309-29.
20. Miller MR, Hankinson J, Brusasco V, etal. Standardisation of spirometry. Eur Respir J 2005;26(2): 319-38.
21. Zapletal A, Samanek M, Paul T. Lung function in children and adolescents. Methods, reference values. Progr Respir Res 1987;22: 113-218.
22. Borrill Z, Clough D, Truman N, Morris J, Langley S, Singh D. A comparison of exhaled nitric oxide measurements performed using three different analysers. Respir Med 2006;100(8): 1392-6.
23. Kissoon N, Duckworth LJ, Blake KV, Murphy SP, Taylor CL, DeNicola LR, Silkoff PE. Exhaled nitric oxide concentrations: online versus offline values in healthy children. Pediatr Pulmonol 2002;33(4): 283-92.
24. Silkoff PE, McClean PA, Slutsky AS, Furlott HG, Hoffstein E, Wakita S, Chapman KR, Szalai JP, Zamel N. Marked flow-dependence of exhaled nitric oxide using a new technique to exclude nasal nitric oxide. Am J Respir Crit Care Med 1997;155(1): 260-7.
25. Carlsen KH, Engh G, Mørk M. Exercise-induced bronchoconstriction depends on exercise load. Respir Med 2000;94(8): 750-5.
26. Kharitonov SA, Chung KF, Evans D, O'Connor BJ, Barnes PJ. Increased exhaled nitric oxide in asthma is mainly derived from the lower respiratory tract. Am J Respir Crit Care Med 1996;153(6 Pt 1): 1773-80.
27. Paraskakis E, Brindicci C, Fleming L, Krol R, Kharitonov SA, Wilson NM, Barnes PJ, Bush A. Measurement of bronchial and alveolar nitric oxide production in normal children and children with asthma. Am J Respir Crit Care Med 2006;174(3): 260-7.
28. Phillips CR, Giraud GD, Holden WE. Exhaled nitric oxide during exercise: site of release and modulation by ventilation and blood flow. J Appl Physiol 1996;80(6): 1865-71.
29. Kissoon N, Duckworth LJ, Blake KV, Murphy SP, Lima JJ. Effect of β2-agonist treatment and spirometry on exhaled nitric oxide in healthy children and children with asthma. Pediatr Pulmonol 2002;34(3): 203-8.
30. Garriga T, Labrador-Horrillo M, Guillén M, Luengo O, Eseverri JL, Guilarte M, Marin AM, Cardona V. Spirometric maneuvers and inhaled salbutamol do not affect exhaled nitric oxide measurements among patients with allergic asthma. Respiration 2012;83: 239-44.