Cigarette smoke increases BLT2 receptor functions in bronchial epithelial cells: In vitro and ex vivo evidence

Immunology

Volumn 139, Issue 2, 2013, Pages 245-255

  Pace, Elisabetta ^a   Ferraro, Maria ^a   Vincenzo, Serena Di ^a   Bruno, Andreina ^a   Giarratano, Antonino ^b   Scafidi, Valeria ^a   Lipari, Luana ^b   Benedetto, Denise Valentina Di ^b   Sciarrino, Serafina ^a   Gjomarkaj, Mark ^a  

^a CNR   (Italy)

^b UNIVERSITY OF PALERMO   (Italy)

Author keywords

Bronchial epithelial cells; chronic obstructive pulmonary disease; Cigarette smoke; Inflammation; Leukotriene B4

Indexed keywords

CIGARETTE SMOKE; INTERCELLULAR ADHESION MOLECULE 1; LEUKOTRIENE B4 RECEPTOR; LEUKOTRIENE B4 RECEPTOR 2; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; STAT1 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BRONCHUS MUCOSA; CELL ADHESION; CONTROLLED STUDY; EPITHELIUM CELL; HUMAN; LUNG FLUID; LUNG LAVAGE; MOLECULAR MECHANICS; NEUTROPHIL; NEUTROPHILIA; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; TISSUE INJURY;

BLOTTING, WESTERN; BRONCHI; BRONCHOALVEOLAR LAVAGE FLUID; CELL ADHESION; CELLS, CULTURED; EPITHELIAL CELLS; FLOW CYTOMETRY; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; NEUTROPHILS; PLANT EXTRACTS; PPAR ALPHA; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RECEPTORS, LEUKOTRIENE B4; RNA INTERFERENCE; SMOKING; STAT1 TRANSCRIPTION FACTOR; TOBACCO;

EID: 84876793840     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12077     Document Type: Article

References (42)

1. Proud D, Leigh R. Epithelial cells and airway diseases. Immunol Rev 2011; 242:186-204.
2. Crooks SW, Bayley DL, Hill SL, Stockley RA. Bronchial inflammation in acute bacterial exacerbations of chronic bronchitis: the role of leukotriene B4. Eur Respir J 2000; 15:274-80.
3. O'Donnell R, Breen D, Wilson S, Djukanovic R. Inflammatory cells in the airways in COPD. Thorax 2006; 61:448-54.
4. Hill AT, Bayley D, Stockley RA. The interrelationship of sputum inflammatory markers in patients with chronic bronchitis. Am J Respir Crit Care Med 1999; 160:893-8.
5. Gompertz S, O'Brien C, Bayley DL, Hill SL, Stockley RA. Changes in bronchial inflammation during acute exacerbations of chronic bronchitis. Eur Respir J 2001; 17:1112-9.
6. Fiedler J, Simon FR, Iwahashi M, Murphy RC. Effect of peroxisome proliferator-activated receptor α activation on leukotriene B4 metabolism in isolated rat hepatocytes. J Pharmacol Exp Ther 2001; 299:691-7.
7. 4. J Immunol 2008; 181:7292-9.
8. Marian E, Baraldo S, Visentin A, Papi A, Saetta M, Fabbri LM, Maestrelli P. Up-regulated membrane and nuclear leukotriene B4 receptors in COPD. Chest 2006; 129:1523-30.
9. Pace E, Giarratano A, Ferraro M, Bruno A, Siena L, Mangione S, Johnson M, Gjomarkaj M. TLR4 upregulation underpins airway neutrophilia in smokers with chronic obstructive pulmonary disease and acute respiratory failure. Hum Immunol 2011; 72:54-62.
10. Su Y, Han W, Giraldo C, De Li Y, Block ER. Effect of cigarette smoke extract on nitric oxide synthase in pulmonary artery endothelial cells. Am J Respir Cell Mol Biol 1998; 19:819-25.
11. Luppi F, Aarbiou J, van Wetering S, Rahman I, de Boer WI, Rabe KF, Hiemstra PS. Effects of cigarette smoke condensate on proliferation and wound closure of bronchial epithelial cells in vitro: role of glutathione. Respir Res 2005; 6:140.
12. Cozens AL, Yezzi MJ, Yamaya M et al. A transformed human epithelial cell line that retains tight junctions post crisis. In Vitro Cell Dev. Biol 1992; 28A:735-44.
13. Seo JM, Cho KJ, Kim EY, Choi MH, Chung BC, Kim JH. Up-regulation of BLT2 is critical for the survival of bladder cancer cells. Exp Mol Med 2011; 43:129-37.
14. Zhang X, Li L, Prabhakaran K, Zhang L, Leavesley HB, Borowitz JL, Isom GE. Uncoupling protein-2 up-regulation and enhanced cyanide toxicity are mediated by PPARα activation and oxidative stress. Toxicol Appl Pharmacol 2007; 223:10-9.
15. Zeidler R, Csanady M, Gires O, Lang S, Schmitt B, Wollenberg B. Tumor cell-derived prostaglandin E2 inhibits monocyte function by interfering with CCR5 and Mac-1. FASEB J 2000; 14:661-8.
16. Pace E, Profita M, Melis M et al. LTB4 is present in exudative pleural effusions and contributes actively to neutrophil recruitment in the inflamed pleural space. Clin Exp Immunol 2004; 135:519-27.
17. Corhay JL, Henket M, Nguyen D, Duysinx B, Sele J, Louis R. Leukotriene B4 contributes to exhaled breath condensate and sputum neutrophil chemotaxis in COPD. Chest 2009; 136:1047-54.
18. Stuart LM, Ezekowitz RA. Phagocytosis: elegant complexity. Immunity 2005; 22:539-50.
19. Nathan C. Neutrophils and immunity: challenges and opportunities. Nat Rev Immunol 2006; 6:173-82.
20. Profita M, Di Giorgi R, Sala A et al. Muscarinic receptors, leukotriene B4 production and neutrophilic inflammation in COPD patients. Allergy 2005; 60:1361-9.
21. Parr DG, White AJ, Bayley DL, Guest PJ, Stockley RA. Inflammation in sputum relates to progression of disease in subjects with COPD: a prospective descriptive study. Respir Res 2006; 7:136.
22. 4 receptors. Prostaglandins Leukot Essent Fatty Acids 2003; 69:123-34.
23. 4 receptor. Am J Respir Cell Mol Biol 2010; 42:294-303.
24. D'Agostino G, La Rana G, Russo R et al. Acute intracerebroventricular administration of palmitoylethanolamide, an endogenous peroxisome proliferator-activated receptor-α agonist, modulates carrageenan-induced paw edema in mice. J Pharmacol Exp Ther 2007; 322:1137-43.
25. De Filippis D, D'Amico A, Cinelli MP, Esposito G, Di Marzo V, Iuvone T. Adelmidrol, a palmitoylethanolamide analogue, reduces chronic inflammation in a carrageenin-granuloma model in rats. J Cell Mol Med 2009; 13:1086-95.
26. Devchand PR, Ijpenberg A, Devesvergne B, Wahli W. PPARs: nuclear receptors for fatty acids, eicosanoids, and xenobiotics. Adv Exp Med Biol 1999; 469:231-6.
27. Chinetti G, Fruchart JC, Staels B. Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation. Inflamm Res 2000; 49:497-505.
28. Okamoto H, Iwamoto T, Kotake S, Momohara S, Yamanaka H, Kamatani N. Inhibition of NF-κB signaling by fenofibrate, a peroxisome proliferator-activated receptor-α ligand, presents a therapeutic strategy for rheumatoid arthritis. Clin Exp Rheumatol 2005; 23:323-30.
29. Delayre-Orthez C, Becker J, Guenon I, Lagente V, Auwerx J, Frossard N, Pons F. PPARα downregulates airway inflammation induced by lipopolysaccharide in the mouse. Respir Res 2005; 6:91.
30. Lee JH, Hanaoka M, Kitaguchi Y, Kraskauskas D, Shapiro L, Voelkel NF, Taraseviciene-Stewart L. Imbalance of apoptosis and cell proliferation contributes to the development and persistence of emphysema. Lung 2012; 190:69-82.
31. Winkler AR, Nocka KH, Sulahian TH, Kobzik L, Williams CM. In vitro modeling of human alveolar macrophage smoke exposure: enhanced inflammation and impaired function. Exp Lung Res 2008; 34:599-629.
32. Chen HW, Chien ML, Chaung YH, Lii CK, Wang TS. Extracts from cigarette smoke induce DNA damage and cell adhesion molecule expression through different pathways. Chem Biol Interact 2004; 150:233-41.
33. Floreani AA, Wyatt TA, Stoner J, Sanderson SD, Thompson EG, Allen-Gipson D, Heires AJ. Smoke and C5a induce airway epithelial intercellular adhesion molecule-1 and cell adhesion. Am J Respir Cell Mol Biol 2003; 29:472-82.
34. Cuzzocrea S, Bruscoli S, Mazzon E et al. PPAR-α contributes to the anti-inflammatory activity of glucocorticoids. Mol Pharmacol 2008; 73:323-37.
35. Papi A, Johnston SL. Rhinovirus infection induces expression of its own receptor intercellular adhesion molecule 1 (ICAM-1) via increased NF-κB-mediated transcription. J Biol Chem 1999; 274:9707-20.
36. Bauer CM, Dewitte-Orr SJ, Hornby KR, Zavitz CC, Lichty BD, Stampfli MR, Mossman KL. Cigarette smoke suppresses Type I interferon-mediated antiviral immunity in lung fibroblast and epithelial cells. J Interferon Cytokine Res 2008; 28:167-79.
37. Greve JM, Davis G, Meyer AM, Forte CP, Connolly Yost S, Marlor CW, Kamarck ME, McClelland A. The major human rhinovirus receptor is ICAM-1. Cell 1989; 56:839-47.
38. Porter JC, Hall A. Epithelial ICAM-1 and ICAM-2 regulate the egression of human T cells across the bronchial epithelium. FASEB J 2009; 23:492-502.
39. Audette M, Larouche L, Lussier I, Fugere N. Stimulation of the ICAM-1 gene transcription by the peroxovanadium compound [bpV(Pic)] involves STAT-1 but not NF-κB activation in 293 cells. Eur J Biochem 2001; 268:1828-36.
40. Eddleston J, Lee RU, Doerner AM, Herschbach J, Zuraw BL. Cigarette smoke decreases innate responses of epithelial cells to rhinovirus infection. Am J Respir Cell Mol Biol 2011; 44:118-26.
41. Dhillon NK, Murphy WJ, Filla MB, Crespo AJ, Latham HA, O'Brien-Ladner A. Down-modulation of IFN-γ signaling in alveolar macrophages isolated from smokers. Toxicol Appl Pharmacol 2009; 237:22-8.
42. Southworth T, Metryka A, Lea S, Farrow S, Plumb J, Singh D. IFN-γ synergistically enhances LPS signalling in alveolar macrophages from COPD patients and controls by corticosteroid resistant STAT1 activation. Br J Pharmacol 2012; 166:2070-83.