The effects of carbohydrate, unsaturated fat, and protein intake on measures of insulin sensitivity: Results from the omniheart trial

Diabetes Care

Volumn 36, Issue 5, 2013, Pages 1132-1137

  Gadgil, Meghana D ^a   Appel, Lawrence J ^a,b,c   Yeung, Edwina ^d   Anderson, Cheryl A M ^b,c   Sacks, Frank M ^e,f   Miller, Edgar R ^a,b,c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

^d EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^e HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^f BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE; GLUCOSE; INSULIN; MONOUNSATURATED FATTY ACID; PROTEIN; UNSATURATED FATTY ACID; CARBOHYDRATE DIET; EDIBLE OIL; PROTEIN INTAKE;

ADULT; ARTICLE; BODY MASS; CARBOHYDRATE DIET; CARBOHYDRATE INTAKE; CARDIOVASCULAR RISK; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIET RESTRICTION; DIET THERAPY; FAT INTAKE; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; INSULIN BLOOD LEVEL; INSULIN SENSITIVITY; LIPID DIET; MACRONUTRIENT; MAJOR CLINICAL STUDY; MALE; METABOLIC PARAMETERS; OUTCOME ASSESSMENT; PREHYPERTENSION; PROTEIN DIET; PROTEIN INTAKE; QUANTITATIVE INSULIN SENSITIVITY CHECK INDEX; RANDOMIZED CONTROLLED TRIAL; WEIGHT REDUCTION; ADMINISTRATION AND DOSAGE; BODY WEIGHT; CARDIOVASCULAR DISEASE; INSULIN RESISTANCE; METABOLISM; MIDDLE AGED; PHYSIOLOGY;

ADULT; BODY WEIGHT; CARDIOVASCULAR DISEASES; CROSS-OVER STUDIES; DIET, HIGH-FAT; DIETARY CARBOHYDRATES; DIETARY FATS, UNSATURATED; DIETARY PROTEINS; FATS, UNSATURATED; FEMALE; HUMANS; INSULIN RESISTANCE; MALE; MIDDLE AGED;

EID: 84876782408     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc12-0869     Document Type: Article

References (40)

1. Nolan CJ, Damm P, Prentki M. Type 2 diabetes across generations: from patho-physiology to prevention and management. Lancet 2011;378:169-181
2. Mokdad AH, Ford ES, Bowman BA, et al. Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001. JAMA 2003;289:76-79 (Pubitemid 36026281)
3. Milman S, Crandall JP. Mechanisms of vascular complications in prediabetes. Med Clin North Am. 2011;95:309-325, vii
4. Reaven GM. The role of insulin resistance and hyperinsulinemia in coronary heart disease. Metabolism 1992;41(Suppl. 1): 16-19
5. Zavaroni I, Bonora E, Pagliara M, et al. Risk factors for coronary artery disease in healthy persons with hyperinsulinemia and normal glucose tolerance. N Engl J Med 1989;320:702-706 (Pubitemid 19072489)
6. Wing RR; Look AHEAD Research Group. Long-term effects of a lifestyle intervention on weight and cardiovascular risk factors in individuals with type 2 diabetes mellitus: four-year results of the Look AHEAD trial. Arch Intern Med 2010;170: 1566-1575
7. Appel LJ, Sacks FM, Carey VJ, et al.; OmniHeart Collaborative Research Group. Effects of protein, monounsaturated fat, and carbohydrate intake on blood pressure and serum lipids: results of the OmniHeart randomized trial. JAMA 2005;294:2455-2464 (Pubitemid 41627923)
8. Katz A, Nambi SS, Mather K, et al. Quantitative insulin sensitivity check index: A simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab 2000;85:2402-2410 (Pubitemid 32269192)
9. Carey VJ, Bishop L, Charleston J, et al. Rationale and design of the optimal macro-nutrient intake heart trial to prevent heart disease (OMNI-heart). Clin Trials 2005;2:529-537 (Pubitemid 43075660)
10. Appel LJ, Moore TJ, Obarzanek E, et al.; DASH Collaborative Research Group. A clinical trial of the effects of dietary patterns on blood pressure. N Engl J Med 1997;336:1117-1124
11. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Ho-meostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985;28: 412-419 (Pubitemid 15018832)
12. Muniyappa R, Lee S, Chen H, Quon MJ. Current approaches for assessing insulin sensitivity and resistance in vivo: Advantages, limitations, and appropriate usage. Am J Physiol Endocrinol Metab 2008; 294:E15-E26
13. Chen H, Sullivan G, Yue LQ, Katz A, Quon MJ. QUICKI is a useful index of insulin sensitivity in subjects with hypertension. Am J Physiol Endocrinol Metab 2003;284:E804-E812 (Pubitemid 36323875)
14. Cheng C, Campbell KL, Kushner H, Falkner BE. Correlation of oral glucose tolerance test-derived estimates of insulin sensitivity with insulin clamp measurements in an African-American cohort. Metabolism 2004;53:1107-1112 (Pubitemid 39140741)
15. Wang R, Lagakos SW, Ware JH, Hunter DJ, Drazen JM. Statistics in medicinedreporting of subgroup analyses in clinical trials. N Engl J Med 2007;357:2189-2194
16. Trichopoulou A, Costacou T, Bamia C, Trichopoulos D. Adherence to a Mediterranean diet and survival in a Greek population. N Engl J Med 2003;348: 2599-2608 (Pubitemid 36741587)
17. Willett WC, Sacks F, Trichopoulou A, et al. Mediterranean diet pyramid: A cultural model for healthy eating. Am J Clin Nutr 1995;61(Suppl.):1402S-1406S
18. Tuomilehto J, Lindström J, Eriksson JG, et al.; Finnish Diabetes Prevention Study Group. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med 2001;344:1343-1350 (Pubitemid 32378388)
19. Knowler WC, Barrett-Connor E, Fowler SE, et al.; Diabetes Prevention Program Research Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 2002;346:393-403 (Pubitemid 34437694)
20. LeRoith D. Dyslipidemia and glucose dysregulation in overweight and obese patients. Clin Cornerstone 2007;8:38-52
21. Shikany JM, Margolis KL, Pettinger M, et al. Effects of a low-fat dietary intervention on glucose, insulin, and insulin resistance in the Women's Health Initiative (WHI) Dietary Modification trial. Am J Clin Nutr 2011;94:75-85
22. Chen H, Sullivan G, Quon MJ. Assessing the predictive accuracy of QUICKI as a surrogate index for insulin sensitivity using a calibration model. Diabetes 2005; 54:1914-1925 (Pubitemid 40911252)
23. Matthews DR. Insulin resistance and beta-cell functionda clinical perspective. Diabetes Obes Metab 2001;3(Suppl. 1):S28-S33 (Pubitemid 33720703)
24. Jebb SA, Lovegrove JA, Griffin BA, et al.; RISCK Study Group. Effectofchangingthe amount andtypeoffat and carbohydrate on insulin sensitivity and cardiovascular risk: the RISCK (Reading, Imperial, Surrey, Cambridge, and Kings) trial. AmJClin Nutr 2010;92:748-758
25. Goree LL, Chandler-Laney P, Ellis AC, Casazza K, Granger WM, Gower BA. Dietary macronutrient composition affects b cell responsiveness but not insulin sensitivity. Am J Clin Nutr 2011;94:120-127
26. Jornayvaz FR, Jurczak MJ, Lee HY, et al. A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain. Am J Physiol Endocrinol Metab 2010;299:E808-E815
27. Lan-Pidhainy X, Wolever TM. The hypo-glycemic effect of fat and protein is not attenuated by insulin resistance. Am J Clin Nutr 2010;91:98-105
28. Manco M, Calvani M, Mingrone G. Effects of dietary fatty acids on insulin sensitivity and secretion. Diabetes Obes Metab 2004; 6:402-413 (Pubitemid 39409791)
29. Micha R, Wallace SK, Mozaffarian D. Red and processed meat consumption and risk of incident coronary heart disease, stroke, and diabetes mellitus: A systematic review and meta-analysis. Circulation 2010;121: 2271-2283
30. Risérus U. Fatty acids and insulin sensitivity. Curr Opin Clin Nutr Metab Care 2008;11:100-105 (Pubitemid 351323169)
31. Aune D, Ursin G, Veierød MB. Meat consumption and the risk of type 2 diabetes: A systematic review and meta-analysis of cohort studies. Diabetologia 2009;52: 2277-2287
32. Sluijs I, Beulens JW, van der A DL, Spijkerman AM, Grobbee DE, van der Schouw YT. Dietary intake of total, animal, and vegetable protein and risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition (EPIC)-NL study. Diabetes Care 2010;33: 43-48
33. Seino S, Shibasaki T, Minami K. Dynamics of insulin secretion and the clinical implications for obesity and diabetes. J Clin Invest 2011;121:2118-2125
34. Romaguera D, Guevara M, Norat T, et al.; InterAct Consortium. Mediterranean diet and type 2 diabetes risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study: the InterAct project. Diabetes Care 2011;34:1913-1918
35. Carnethon MR, De Chavez PJ, Biggs ML, et al. Association of weight status with mortality in adults with incident diabetes. JAMA 2012;308:581-590
36. Furtado JD, Campos H, Appel LJ, et al. Effect of protein, unsaturated fat, and carbohydrate intakes on plasma apolipoprotein B and VLDL and LDL containing apolipo-protein C-III: results from the OmniHeart Trial. Am J Clin Nutr 2008;87:1623-1630 (Pubitemid 351872623)
37. Furtado JD, Campos H, Sumner AE, Appel LJ, Carey VJ, Sacks FM. Dietary interventions that lower lipoproteins containing apolipoprotein C-III are more effective in whites than in blacks: results of the OmniHeart trial. Am J Clin Nutr 2010;92:714-722
38. Yeung EH, Appel LJ, Miller ER 3rd, Kao WH. The effects of macronutrient intake on total and high-molecular weight adipo-nectin: results from the OMNI-Heart trial. Obesity (Silver Spring) 2010;18:1632-1637
39. Acheson KJ. Carbohydrate for weight and metabolic control: where do we stand? Nutrition 2010;26:141-145
40. Austin GL, Ogden LG, Hill JO. Trends in carbohydrate, fat, and protein intakes and association with energy intake in normal-weight, overweight, and obese individuals: 1971-2006. Am J Clin Nutr 2011;93:836-843