Dynamic subcellular imaging of cancer cell mitosis in the brain of live mice

Anticancer Research

Volumn 33, Issue 4, 2013, Pages 1367-1372

  Momiyama, Masashi ^a,b,c   Suetsugu, Atsushi ^a   Kimura, Hiroaki ^a   Chishima, Takashi ^c   Bouvet, Michael ^b   Endo, Itaru ^c   Hoffman, Robert M ^a,b  

^a ANTICANCER INC   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

Brain cancer; Brain metastasis; Craniotomy window; GFP; In vivo imaging; Mitosis; Mouse model; RFP; Subcellular dynamics

Indexed keywords

GREEN FLUORESCENT PROTEIN; RED FLUORESCENT PROTEIN;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BRAIN; BRAIN CANCER; BRAIN METASTASIS; CANCER CELL; CRANIOTOMY; CYTOPLASM; FLUORESCENCE IMAGING; HUMAN; HUMAN CELL; MITOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN FLAP;

ANIMALS; BRAIN NEOPLASMS; CARCINOMA, LEWIS LUNG; CELL NUCLEUS; CRANIOTOMY; CYTOPLASM; DIAGNOSTIC IMAGING; GLIOMA; GREEN FLUORESCENT PROTEINS; HUMANS; LUMINESCENT PROTEINS; MICE; MICE, NUDE; MICROSCOPY, FLUORESCENCE; MITOSIS; TUMOR CELLS, CULTURED;

EID: 84876777474     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Cruz-Munoz W, Man S, Xu P and Kerbel RS: Development of a preclinical model of spontaneous human melanoma central nervous system metastasis. Cancer Res 68: 4500-4505, 2008.
2. Tarhini AA and Agarwala SS: Cutaneous melanoma: Available therapy for metastatic disease. Dermatol Ther 19: 19-25 (2006).
3. Lin NU and Winer EP: Brain metastases: The HER2 paradigm. Clin Cancer Res 13: 1648-1655, 2007. (Pubitemid 46952930)
4. Mayer M: A patient perspective on brain metastases in breast cancer. Clin Cancer Res 13: 1623-1624, 2007. (Pubitemid 46952924)
5. Palmieri D, Chambers AF, Felding-Habermann B, Huang S and Steeg PS: The biology of metastasis to a sanctuary site. Clin Cancer Res 13: 1656-1662, 2007. (Pubitemid 46957363)
6. Hoffman RM: The multiple uses of fluorescent proteins to visualize cancer in vivo. Nat Rev Cancer 5: 796-806, 2005. (Pubitemid 41400779)
7. Yang M, Jiang P, Sun FX, Hasegawa S, Baranov E, Chishima T, Shimada H, Moossa AR and Hoffman RM: A fluorescent orthotopic bone metastasis model of human prostate cancer. Cancer Res 59: 781-786, 1999. (Pubitemid 29086726)
8. Yang M, Jiang P, An Z, Baranov E, Li L, Hasegawa S, Al-Tuwaijri M, Chishima T, Shimada H, Moossa AR and Hoffman RM: Genetically fluorescent melanoma bone and organ metastasis models. Clin Cancer Res 5: 3549-3559, 1999.
9. Hayashi K, Yamauchi K, Yamamoto N, Tsuchiya H, Tomita K, Bouvet M, Wessels J and Hoffman RM: A color-coded orthotopic nude-mouse treatment model of brain-metastatic paralyzing spinal cord cancer that induces angiogenesis and neurogenesis. Cell Proliferation 42: 75-82, 2009.
10. Kienast Y, von Baumgarten L, Fuhrmann M, Klinkert WE, Goldbrunner R, Herms J and Winkler F: Real-time imaging reveals the single steps of brain metastasis formation. Nat Med 16: 116-122, 2010.
11. Yamamoto N, Jiang P, Yang M, Xu M, Yamauchi K, Tsuchiya H, Tomita K, Wahl GM, Moossa AR and Hoffman RM: Cellular dynamics visualized in live cells in vitro and in vivo by differential dual-color nuclear-cytoplasmic fluorescent-protein expression. Cancer Res 64: 4251-4256, 2004. (Pubitemid 38802430)
12. Momiyama M, Suetsugu A, Kimura H, Kishimoto H, Aki R, Yamada A, Sakurada H, Chishima T, Bouvet M, Endo I and Hoffman RM: Imaging the efficacy of UVC irradiation on superficial brain tumors and metastasis in live mice at the subcellular level. J Cell Biochem 114: 428-434, 2013.
13. Momiyama M, Suetsugu A, Chishima T, Bouvet M, Endo I and Hoffman RM: Subcellular real-time imaging of the efficacy of temozolomide on cancer cells in the brain of live mice. Anticancer Res 33: 103-106, 2013.
14. Yamauchi K, Yang M, Jiang P, Xu M, Yamamoto N, Tsuchiya H, Tomita K, Moossa AR, Bouvet M and Hoffman RM: Development of real-time subcellular dynamic multicolor imaging of cancer-cell trafficking in live mice with a variable-magnification whole-mouse imaging system. Cancer Res 66: 4208-4214, 2006.
15. Uchugonova A, Duong J, Zhang N, König K and Hoffman RM. The bulge area is the origin of nestin-expressing pluripotent stem cells of the hair follicle. J Cell Biochem 111: 2046-2050, 2011.
16. Winkler F, Kienast Y, Fuhrmann M, Von Baumgarten L, Burgold S, Mitteregger G, Kretzschmar H and Herms J: Imaging glioma cell invasion in vivo reveals mechanisms of dissemination and peritumoral angiogenesis. Glia 57: 1306-1315, 2009.