CORAL: Binary classifications (active/inactive) for liver-related adverse effects of drugs

Current Drug Safety

Volumn 7, Issue 4, 2012, Pages 257-261

  Toropov, Andrey A ^a   Toropova, Alla P ^a   Rasulev, Bakhtiyor F ^b   Benfenati, Emilio ^a   Gini, Giuseppina ^c   Leszczynska, Danuta ^d   Leszczynski, Jerzy ^b  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b JACKSON STATE UNIVERSITY   (United States)

^c POLITECNICO DI MILANO   (Italy)

^d Jackson State University   (United States)

Author keywords

Binary classification; CORAL software; Liver related adverse effect; Method monte carlo; Optimal descriptor; QSAR

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE;

ADVERSE DRUG REACTION; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CHEMICAL STRUCTURE; COMPUTER PROGRAM; ENZYME ACTIVITY; LIVER TOXICITY; MONTE CARLO METHOD; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SENSITIVITY AND SPECIFICITY;

ALANINE TRANSAMINASE; ASPARTATE AMINOTRANSFERASES; DRUG-INDUCED LIVER INJURY; HUMANS; MODELS, MOLECULAR; MONTE CARLO METHOD; PHARMACEUTICAL PREPARATIONS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SOFTWARE;

EID: 84876740860     PISSN: 15748863     EISSN: None     Source Type: Journal    
DOI: 10.2174/157488612804096542     Document Type: Article

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