Nitric oxide and carbon monoxide production and metabolism in preeclampsia

Reproductive Sciences

Volumn 20, Issue 5, 2013, Pages 542-548

  Ehsanipoor, Robert M ^a,b   Fortson, Wilbert ^a,c   Fitzmaurice, Laura E ^a,d   Liao, Wu Xiang ^a   Wing, Deborah A ^a   Chen, Dong Bao ^a   Chan, Kenneth ^e  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Perinatal Center of Savannah   (United States)

^d KAISER PERMANENTE   (United States)

^e MILLER CHILDREN S HOSPITAL   (United States)

Author keywords

asymmetric dimethylarginine; carbon monoxide; hemeoxygenase; nitric oxide; preeclampsia

Indexed keywords

6 N,N' DIMETHYLARGININE; AMINOTRANSFERASE; CARBON MONOXIDE; DIMETHYLARGININE DIMETHYLAMINOTRANSFERASE; HEME OXYGENASE 1; N(G),N(G) DIMETHYLARGININE; NITRIC OXIDE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN TISSUE; MATERNAL PLASMA; METABOLISM; PLACENTA; PREECLAMPSIA; PRIORITY JOURNAL; WESTERN BLOTTING;

ADULT; AMIDOHYDROLASES; ARGININE; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CARBON MONOXIDE; CASE-CONTROL STUDIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HEME OXYGENASE-1; HUMANS; NITRIC OXIDE; PLACENTA; PRE-ECLAMPSIA; PREDICTIVE VALUE OF TESTS; PREGNANCY; PROSPECTIVE STUDIES; YOUNG ADULT;

EID: 84876732654     PISSN: 19337191     EISSN: 19337205     Source Type: Journal    
DOI: 10.1177/1933719112459231     Document Type: Article

References (23)

1. Sibai BM. Diagnosis and management of gestational hypertension and preeclampsia. Obstet Gynecol. 2003 ; 102 (1). 181-192
2. Merviel P, Carbillon L, Challier JC, Rabreau M, Beaufils M, Uzan S. Pathophysiology of preeclampsia: links with implantation disorders. Eur J Obstet Gynecol Reprod Biol. 2004 ; 115 (2). 134-147
3. Boger RH, Diemert A, Schwedhelm E, Luneburg N, Maas R, Hecher K. The role of nitric oxide synthase inhibition by asymmetric dimethylarginine in the pathophysiology of preeclampsia. Gynecol Obstet Invest. 2010 ; 69 (1). 1-13
4. Bainbridge SA, Smith GN. HO in pregnancy. Free Radic Biol Med. 2005 ; 38 (8). 979-988
5. Fickling SA, Williams D, Vallance P, Nussey SS, Whitley GS. Plasma concentrations of endogenous inhibitor of nitric oxide synthesis in normal pregnancy and pre-eclampsia. Lancet. 1993 ; 342 (8865). 242-243
6. Holden DP, Fickling SA, Whitley GS, Nussey SS.. Plasma concentrations of asymmetric dimethylarginine, a natural inhibitor of nitric oxide synthase, in normal pregnancy and preeclampsia. Am J Obstet Gynecol. 1998 ; 178 (3). 551-556
7. Speer PD, Powers RW, Frank MP, Harger G, Markovic N, Roberts JM.. Elevated asymmetric dimethylarginine concentrations precede clinical preeclampsia, but not pregnancies with small-for-gestational-age infants. Am J Obstet Gynecol. 2008 ; 198 (1). e1-112
8. Pettersson A, Hedner T, Milsom I.. Increased circulating concentrations of asymmetric dimethyl arginine (ADMA), an endogenous inhibitor of nitric oxide synthesis, in preeclampsia. Acta Obstet Gynecol Scand. 1998 ; 77 (8). 808-813
9. Ellis J, Wennerholm UB, Bengtsson A, et al. Levels of dimethylarginines and cytokines in mild and severe preeclampsia. Acta Obstet Gynecol Scand. 2001 ; 80 (7). 602-608
10. Braekke K, Ueland PM, Harsem NK, Staff AC. Asymmetric dimethylarginine in the maternal and fetal circulation in preeclampsia. Pediatr Res. 2009 ; 66 (4). 411-415
11. Mao D, Che J, Li K, et al. Association of homocysteine, asymmetric dimethylarginine, and nitric oxide with preeclampsia. Arch Gynecol Obstet. 2010 ; 282 (4). 371-375
12. Maas R, Boger RH, Schwedhelm E, et al. Plasma concentrations of asymmetric dimethylarginine (ADMA) in Colombian women with pre-eclampsia. JAMA. 2004 ; 291 (7). 823-824
13. Siroen MP, Teerlink T, Bolte AC, et al. No compensatory upregulation of placental dimethylarginine dimethylaminohydrolase activity in preeclampsia. Gynecol Obstet Invest. 2006 ; 62 (1). 7-13
14. King RG, Di Iulio JL, Gude NM, Brennecke SP. Effect of asymmetric dimethyl arginine on nitric oxide synthase activity in normal and pre-eclamptic placentae. Reprod Fertil Dev. 1995 ; 7 (6). 1581-1584
15. Pope AJ, Karuppiah K, Cardounel AJ. Role of the PRMT-DDAH-ADMA axis in the regulation of endothelial nitric oxide production. Pharmacol Res. 2009 ; 60 (6). 461-465
16. Ahmed A, Rahman M, Zhang X, et al. Induction of placental heme oxygenase-1 is protective against TNFalpha-induced cytotoxicity and promotes vessel relaxation. Mol Med. 2000 ; 6 (5). 391-409
17. Barber A, Robson SC, Myatt L, Bulmer JN, Lyall F. Heme oxygenase expression in human placenta and placental bed: reduced expression of placenta endothelial HO-2 in preeclampsia and fetal growth restriction. FASEB J. 2001 ; 15 (7). 1158-1168
18. Brown MA, Lindheimer MD, de Swiet M, Van Assche A, Moutquin JM.. The classification and diagnosis of the hypertensive disorders of pregnancy: statement from the International Society for the Study of Hypertension in Pregnancy (ISSHP). Hypertens Pregnancy. 2001 ; 20 (1). IX - XIV
19. Liao WX, Magness RR, Chen DB. Expression of estrogen receptors-alpha and -beta in the pregnant ovine uterine artery endothelial cells in vivo and in vitro. Biol Reprod. 2005 ; 72 (3). 530-537
20. McLaughlin BE, Lash GE, Smith GN, et al. Heme Oxygenase Expression in Selected Regions of Term Human Placenta. Exp Biol Med. 2003 ; 228 (5). 564-567
21. Akbar F, Heinonen S, Pirskanen M, Uimari P, Tuomainen TP, Salonen JT. Haplotypic association of DDAH1 with susceptibility to pre-eclampsia. Mol Hum Reprod. 2005 ; 11 (1). 73-77
22. Vadillo-Ortega F, Perichart-Perera O, Espino S, et al. Effect of supplementation during pregnancy with L-arginine and antioxidant vitamins in medical food on pre-eclampsia in high risk population: randomised controlled trial. BMJ. 2011 ; 342: d2901
23. Rytlewski K, Olszanecki R, Korbut R, Zdebski Z. Effects of prolonged oral supplementation with l-arginine on blood pressure and nitric oxide synthesis in preeclampsia. Eur J Clin Invest. 2005 ; 35 (1). 32-37