Tissue and cellular localization of nanoparticles using 35S labeling and light microscopic autoradiography

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 9, Issue 4, 2013, Pages 465-468

  Holzhausen, Cornelia ^a   Gröger, Dominic ^a   Mundhenk, Lars ^a   Welker, Pia ^b   Haag, Rainer ^a   Gruber, Achim D ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b Mivenion GmbH   (Germany)

Author keywords

Light microscopy; Mouse model; Nanoparticles; Radioisotope; Toxicopathology

Indexed keywords

ANTI-INFLAMMATORIES; CELLULAR LOCALIZATION; CELLULAR MICROENVIRONMENT; INTRAVENOUS INJECTIONS; MOUSE MODELS; ORGANIC NANOPARTICLES; PHYSICOCHEMICAL PROPERTY; TOXICOPATHOLOGY;

MAMMALS; NANOPARTICLES; OPTICAL MICROSCOPY; RADIOGRAPHY; RADIOISOTOPES; TOXICITY;

TISSUE;

DENDRITIC POLYGLYCEROL SULFATE AMINE; NANOPARTICLE; SULFATE; SULFUR 35; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CELLULAR DISTRIBUTION; ISOTOPE LABELING; KUPFFER CELL; LIGHT MICROSCOPIC AUTORADIOGRAPHY; MICROSCOPY; MOUSE; NONHUMAN;

ANIMALS; AUTORADIOGRAPHY; MICE; MICROSCOPY; NANOPARTICLES; SULFUR RADIOISOTOPES;

MUS;

EID: 84876731133     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2013.02.003     Document Type: Article

References (11)

1. Dernedde J., Rausch A., Weinhart M., Enders S., Tauber R., Licha K., et al. Dendritic polyglycerol sulfates as multivalent inhibitors of inflammation. Proc Natl Acad Sci 2010, 107:19679-19684.
2. Oberdörster Günter O.E., Oberdörster J. Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect 2005, 113:823-839.
3. Terje D., Werner H.D., Mah L.N.M., Jan-Thorsten S. Techniques in microscopy for biomedical applications. Manuals in biomedical research: World Scientific Publishing Co. Pte. Ltd 2006, J-T S (Ed.).
4. Almutairi A., Akers W.J., Berezin M.Y., Achilefu S., Fréchet J.M.J. Monitoring the biodegradation of dendritic near-infrared nanoprobes by in vivo fluorescence imaging. Mol Pharm 2008, 5:1103-1110.
5. Saxena V., Sadoqi M., Shao J. Polymeric nanoparticulate delivery system for indocyanine green: biodistribution in healthy mice. Int J Pharm 2006, 308:200-204.
6. Janib S.M., Moses A.S., MacKay J.A. Imaging and drug delivery using theranostic nanoparticles. Adv Drug Deliv Rev 2010, 62:1052-1063.
7. Weinhart M., Gröger D., Enders S., Riese S.B., Dernedde J., Kainthan R.K., et al. The role of dimension in multivalent binding events: structure-activity relationship of dendritic polyglycerol sulfate binding to l-selectin in correlation with size and surface charge density. Macromol Biosci 2011, 11:1088-1098.
8. Marquis B.J., Love S.A., Braun K.L., Haynes C.L. Analytical methods to assess nanoparticle toxicity. Analyst 2009, 134:425-439.
9. Kocher DC. Radioactive decay data tables: a handbook of decay data for application to radiation dosimetry and radiological assessments. [Oak Ridge, Tenn.]; Springfield, Va.: Technical Information Center, U.S. Dept. of Energy; Available from National Technical Information Service, U.S. Dept. of Commerce; 1981.
10. Scott J.E. Histochemistry of alcian blue. Histochem Cell Biol 1972, 30:215-234.
11. Agrawal S., Temsamani J., Tang J.Y. Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice. PNAS 1991, 88:7595-7599.