Effect of lipopolysaccharide on alteration of phospholipids and their fatty acid composition in spleen and thymus by in vitro metabolic labeling

Journal of Applied Toxicology

Volumn 33, Issue 6, 2013, Pages 418-425

  Sabarirajan, Jayaraja ^a   Vijayaraj, Panneerselvam ^a   Sarkar, Mary ^b   Nachiappan, Vasanthi ^a  

^a BHARATHIDASAN UNIVERSITY   (India)

^b INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

32P labeling; Fatty acid; LPS; Phospholipid metabolism; Spleen; Thymus

Indexed keywords

LIPOPOLYSACCHARIDE; PHOSPHATE P 32; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLGLYCEROL; SATURATED FATTY ACID; UNSATURATED FATTY ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; FATTY ACID ANALYSIS; IMMUNOPATHOLOGY; IN VITRO STUDY; ISOTOPE LABELING; LIPID COMPOSITION; MALE; NONHUMAN; PHOSPHOLIPID METABOLISM; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SPLEEN; THYMUS;

ANALYSIS OF VARIANCE; ANIMALS; AUTORADIOGRAPHY; CHROMATOGRAPHY, THIN LAYER; FATTY ACIDS; ISOTOPE LABELING; LIPOPOLYSACCHARIDES; MALE; PHOSPHATES; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLGLYCEROLS; PHOSPHOLIPIDS; PHOSPHORUS RADIOISOTOPES; RATS; RATS, WISTAR; SPLEEN; THYMUS GLAND;

RATTUS;

EID: 84876727717     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1752     Document Type: Article

References (48)

1. Bennett M, Uauy R, Grundy SM. 1987. Dietary fatty acid effects on T-cell-mediated immunity in mice infected with mycoplasma pulmonis or given carcinogens by injection. Am. J. Pathol. 126: 103-113.
2. Billah MM, Anthes JC. 1990. The regulation and cellular functions of phosphatidylcholine hydrolysis. Biochem. J. 269: 281-291.
3. Bohnsack JF, Brown EJ. 1986. The role of the spleen in resistance to infection. Annu. Rev. Med. 37: 49-59.
4. Buttke TM. 1984. Inhibition of lymphocyte proliferation by free fatty acids. I. Differential effects on mouse B and T lymphocytes. Immunology 53: 235-242.
5. Calder PC, Yaqoob P, Harvey DJ, Watts A, Newsholme EA. 1994. Incorporation of fatty acids by concanavalin A-stimulated lymphocytes and the effect on fatty acid composition and membrane fluidity. Biochem. J. 300: 509-518.
6. Chew BP, Wong TS, Shultz TD, Magnuson NS. 1997. Effects of conjugated dienoic derivatives of linoleic acid and beta-carotene in modulating lymphocyte and macrophage function. Anticancer Res. 17: 1099-1106.
7. Cui Z, Houweling M. 2002. Phosphatidylcholine and cell death. Biochim. Biophys. Acta 1585: 87-96.
8. 32P labeling of individual kephalins and lecithin in a small sample of tissue. Biochim. Biophys. Acta 14: 374-379.
9. DeLong CJ, Shen Y, Thomas MJ, Cui Z. 1999. Molecular distinction of phosphatidylcholine synthesis between the CDP-choline pathway and phosphatidylethanolamine methylation pathway. J. Biol. Chem. 274: 29683-29688.
10. Engelhardt M, Haas PS, Theilacker C, Eber SW, Schmugge M, Kern WV, Heimpel H. 2009. Prevention of infections and thromboses after splenectomy or because of functional loss of the spleen. Dtsch. Med. Wochenschr. 134(17): 897-902.
11. Erickson KL. 1986. Dietary fat modulation of immune response. Int. J. Immunopharmacol. 8(6): 529-543.
12. Erickson KL, McNeill CJ, Gershwin ME, Ossmann JB. 1980. Influence of dietary fat concentration and saturation on immune ontogeny in mice. J. Nutr. 110: 1555-1572.
13. Exton JH. 1994. Phosphatidylcholine breakdown and signal transduction. Biochim. Biophys. Acta 1212: 26-42.
14. Ferber E, Egabriel G, De Pasquale GG, Resch K. 1975. Phospholipid metabolism of stimulated lymphocytes composition of phospholipid fatty acids. Biochim. Biophys. Acta 398(3): 364-376.
15. Folch JM, Lees T, Sloane stanely GH. 1957. A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 226(1): 497-510.
16. Gimenez MS, Oliveros LB, Gomez NN. 2011. Nutritional deficiencies and phospholipid metabolism. Int. J. Mol. Sci. 12(4): 2408-2433.
17. Gurr MI. 1983. The role of lipids in the regulation of the immune system. Prog. Lipid Res. 22(4): 257-287.
18. Hayek MG, Han SN, Wu D, Watkins BA, Meydani M, Dorsey JL, Smith DE, Meydani SN. 1999. Dietary conjugated linoleic acid influences the immune response of young and old C57BL/6NCrlBR mice. J. Nutr. 129(1): 32-38.
19. Hong R. 2001. The thymus: finally getting some respect. Chest Surg. Clin. N. Am. 11: 295-310.
20. Kester M, Simonson MS, Mene P, Sedor JR. 1989. Interleukin-1 generates transmembrane signals from phospholipids through novel pathways in cultured rat mesangial cells. J. Clin. Invest. 83: 718-723.
21. Kiss Z. 1990. Effects of phorbol ester on phospholipid metabolism. Prog. Lipid Res. 29: 141-166.
22. Lee TH, Austen KF. 1986. Arachidonic acid metabolism by the 5-lipoxygenase pathway, and the effects of alternative dietary fatty acids. Adv. Immunol. 39: 145-175.
23. Li Z, Vance DE. 2008. Phosphatidylcholine and choline homeostatis. J. Lipid Res. 49: 1187-1194.
24. Maes M, Smith R, Christophe A, Cosyns P, Desnyder R, Meltzer H. 1996. Fatty acid composition in major depression: decreased omega 3 fractions in cholesteryl esters and increased C20:4 omega 6/C20:5 omega 3 ratio in cholesteryl esters and phospholipids. J. Affect. Disord. 38: 35-46.
25. Maes M, Smith R, Christophe A, Vandoolaeghe E, Van Gastel A, Neels H, Demedts P, Wauters A, Meltzer HY. 1997. Lower serum high-density lipoprotein cholesterol (HDL-C) in major depression and in depressed men with serious suicidal attempts: relationship with immune-inflammatory markers. Acta Psychiatr. Scand. 95: 212-221.
26. 32P-orthophosphate into phosphatides of rat tissues. Biochim. Biophys. Acta 30: 543-548.
27. Mattson MP. 2000. Apoptosis in neurodegenerative disorders. Nat. Rev. Mol. Cell Biol. 1: 120-129.
28. Meade CJ, Mertin J. 1978. Fatty acids and immunity. Adv. Lipid Res. 16: 127-165.
29. Mebius RE, Kraal G. 2005. Structure and function of the spleen. Nat. Rev. Immunol. 5(8): 606-616.
30. Morrison WR, Smith LM. 1964. Preparation of fatty acid methyl esters and dimethylacetals from lipids with boron fluoride-methanol. J. Lipid Res. 5: 600-608.
31. Niehaus I, Lange JH. 2003. Endotoxin: is it an environmental factor in the cause of Parkinson's disease? Occup. Environ. Med. 60(5): 378.
32. Ordway RW, Singer JJ, Walsh JV. 1991. Direct regulation of ion channels by fatty acids. Trends Neurosci. 14: 96-100.
33. Peet M, Murphy B, Shay J, Horrobin D. 1998. Depletion of omega-3 fatty acid levels in red blood cell membranes of depressive patients. Biol. Psychiat. 43: 315-319.
34. Pourbohloul S, Mallett GS, Buttke TM. 1985. Inhibition of lymphocyte proliferation by free fatty acids. III. Modulation of thymus-dependent immune responses. Immunology 56: 659-666.
35. Rothfield L, Romeo D. 1971. Role of lipids in the biosynthesis of the bacterial cell envelope. Bacteriol. Rev. 35: 14-38.
36. Sabarirajan J, Vijayaraj P, Nachiappan V. 2010. Induction of acute respiratory distress syndrome in rats by lipopolysaccharide and its effect on oxidative stress and antioxidant status in lung. Indian J. Biochem. Biophys. 47: 278-284.
37. Schlame M, Rua D, Greenberg ML. 2000. The biosynthesis and functional role of cardiolipin. Prog. Lipid Res. 39: 257-288.
38. Shier WT, Baldwin JH, Nilsen-Hamilton M, Hamilton RT, Thanassi NM. 1976. Regulation of guanylate and adenylate cyclase activities by lysolecithin. Proc. Natl Acad. Sci. USA 73: 1586-1590.
39. Siddiqui RA, Shaikh SR, Sech LA, Yount HR, Stillwell W, Zaloga GP. 2004. Omega 3-fatty acids: health benefits and cellular mechanisms of action. Mini Rev. Med. Chem. 4: 859-871.
40. Smith AD, Conroy DM, Belin J. 1985. Membrane lipid modification and immune function. Proc. Nutr. Soc. 44: 201-209.
41. Stenger PC, Alonso C, Zasadzinski JA, Waring AJ, Jung CL, Pinkerton KE. 2009. Environmental tobacco smoke effects on lung surfactant film organization. Biochim. Biophys. Acta 1788: 358-370.
42. Swirski FK, Nahrendorf M, Etzrodt M, Wildgruber M, Cortez-Retamozo V, Panizzi P, Figueiredo JL, Kohler RH, Chudnovskiy A, Waterman P, Aikawa E, Mempel TR, Libby P, Weissleder R, Pittet MJ. 2009. Identification of splenic reservoir monocytes and their deployment to inflammatory sites. Science 325: 612-616.
43. Turek JJ, Li Y, Schoenlein IA, Allen KGD, Watkins BA. 1998. Modulation of macrophage cytokine production by conjugated linoleic acids is influenced by the dietary n-6:n-3 fatty acid ratio. J. Nutr. Biochem. 9: 258-266.
44. Van Den Bosch H. 1974. Phosphoglyceride metabolism. Annu. Rev. Biochem. 43: 243-277.
45. White MK, McCubrey JA. 2001. Suppression of apoptosis: role in cell growth and neoplasia. Leukemia 15: 1011-1021.
46. Yamashita A, Sugiura T, Waku K. 1997. Acyltransferases and transacylases involved in fatty acid remodeling of phospholipids and metabolism of bioactive lipids in mammalian cells. J. Biochem. 122: 1-16.
47. Yang M, Cook ME. 2003. Dietary conjugated linoleic acid decreased cachexia, macrophage tumor necrosis factor-alpha production, and modifies splenocyte cytokines production. Exp. Biol. Med. 228: 51-58.
48. Yorio T, Frazier LW. 1990. Phospholipids and electrolyte transport. Proc. Soc. Exp. Biol. Med. 195: 293-303.