Autoimmune hepatitis-primary biliary cirrhosis overlap syndrome concomitant with immune hemolytic anemia and immune thrombocytopenic purpura (Evans syndrome)

Clinics and Research in Hepatology and Gastroenterology

Volumn 37, Issue 2, 2013, Pages

  Korkmaz, Huseyin ^a   Bugdaci, Mehmet Sait ^b   Temel, Tuncer ^c   Dagli, Mehmet ^a   Karabagli, Pinar ^a  

^a SELCUK UNIVERSITY   (Turkey)

^b Konya Education and Research Hospital   (Turkey)

^c ESKISEHIR OSMANGAZI UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; AMINOTRANSFERASE; ANTIMITOCHONDRIAL M2 ANTIBODY; ANTINUCLEAR ANTIBODY; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; BILIRUBIN GLUCURONIDE; GAMMA GLUTAMYLTRANSFERASE; IMMUNOGLOBULIN G; MITOCHONDRION ANTIBODY; PREDNISOLONE; UNCLASSIFIED DRUG; URSODEOXYCHOLIC ACID;

ADULT; ANEMIA; ARTHRALGIA; ARTICLE; AUTOIMMUNE HEMOLYTIC ANEMIA; AUTOIMMUNE HEPATITIS; BONE MARROW BIOPSY; CASE REPORT; DISEASE ASSOCIATION; DRUG DOSE REDUCTION; DYSPNEA; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; GENETIC SUSCEPTIBILITY; HUMAN; HUMAN TISSUE; IDIOPATHIC THROMBOCYTOPENIC PURPURA; LIVER BIOPSY; LIVER DYSFUNCTION; MYALGIA; PRIMARY BILIARY CIRRHOSIS; PURPURA; THROMBOCYTOPENIA; WEAKNESS;

ANEMIA, HEMOLYTIC, AUTOIMMUNE; ANTIBODIES, ANTINUCLEAR; AUTOANTIBODIES; CHOLAGOGUES AND CHOLERETICS; FEMALE; GLUCOCORTICOIDS; HEPATITIS, AUTOIMMUNE; HUMANS; IMMUNOGLOBULINS, INTRAVENOUS; LIVER CIRRHOSIS, BILIARY; MIDDLE AGED; MITOCHONDRIA, LIVER; PREDNISOLONE; THROMBOCYTOPENIA; URSODEOXYCHOLIC ACID;

EID: 84876723067     PISSN: 22107401     EISSN: 2210741X     Source Type: Journal    
DOI: 10.1016/j.clinre.2012.11.001     Document Type: Article

References (26)

1. Beuers U. Hepatic overlap syndromes. J Hepatol 2005, 42:93-99.
2. Rust C., Beuers U. Overlap syndromes among autoimmune liver diseases. World J Gastroenterol 2008, 14:3368-3373.
3. Czaja A.J. The variant forms of a autoimmune hepatitis. Ann Intern Med 1996, 125:588-598.
4. Watt F.E., James O.F., Jones D.E. Patterns of autoimmunity in primary biliary cirrhosis patients and their families: a population-based cohort study. QJM 2004, 97:397-406.
5. Alverez F., Berg P.A., Bianchi F.B., Bianchi L., Burroughs A.K., Cancado E.L., et al. International Autoimmune Hepatitis Group Report; review of criteria for diagnosis of autoimmune hepatitis. J Hepatol 1999, 31:929-938.
6. Hennes E.M., Zeniya M., Czaja A.J., Pares A., Dalekos G.N., Krawitt E.L., et al. Simplified criteria for the diagnosis of autoimmune hepatitis. Hepatology 2008, 48:169-176.
7. Poupon R., Chazouillers O., Corpechot C., Chretien Y. Development of autoimmune hepatitis in patients with typical primary biliary cirrhosis. Hepatology 2006, 44:85-90.
8. Talwalkar J.A., Keach J.C., Angulo P., Lindor K.D. Overlap of autoimmune hepatitis and primary biliary cirrhosis: an evaluation of a modified scoring system. Am J Gastroenterol 2002, 97:1191-1207.
9. Farias A.Q., Goncalves L.L., Bittencourt P.L., De Melo E.S., Abrantes-Lemo C.P., Porta G., et al. Applicability of the IAIHG scorroing system to the diagnosis of antimitochondrial/anti-M2 seropositive variant form of autoimmune hepatitis. J Gastroenterol Hepatol 2006, 21:887-893.
10. Chazouilleres O., Wendum D., Serfaty L., Montembault S., Rosmorduc O., Poupon R. Primary biliary cirrhosis-autoimmune hepatitis overlap syndrome: clinical features and response to therapy. Hepatology 1998, 28:296-301.
11. Europan Association for the Study of the liver EASL clinical practice guidelines: management of cholestatic liver diseases. J Hepatol 2009, 51:237-267.
12. Czaja A. Frequency and nature of the variant syndromes of autoimmune liver disease. Hepatology 1998, 28:360-365.
13. Kenny R.P., Czaja A.J., Ludwig J., Dickson E.R. Frequency and significance of antimitochondrial antibodies in severe chronic active hepatitis. Dig Dis Sci 1986, 31:705-711.
14. Lohse A.W., Buschenfelde K.H., Franz B., Kanzler S., Dienes H.P. Characterization of the overlap syndrome of primary biliary cirrhosis (PBC) and autoimmune hepatitis: evidence for it being a hepatitic form of PBC in genetically susceptible individuals. Hepatology 1999, 29:1078-1084.
15. Mathew P., Chen G., Wang W. Evans syndrome: result of a national survey. J Pediatr Hematol Oncol 1997, 19:433-437.
16. Azad A., Berera V., Jayarajan J., Lim K. Evans syndrome and primary biliary cirrhosis. Int Jnl Lab Hem 2007, 29:145-148.
17. Wang W, Herrod H., Pui C.H., Presbury G., Willimas J. Immunregulatory abnormalities in Evans' syndrome. Am J Hematol 1983, 15:381-390.
18. Chong B.H., Ho S.J. Autoimmune thrombocytopenia: review. J Thromb Haemost 2005, 3:1763-1772.
19. Panzer S., Penner E., Nelson P.J., Benda H., Saurugger P.N. Identification of the platelet glycoprotein IIb/IIIa complex as a target antigen in primary biliary cirrhosis-associated autoimmune thrombocytopenia. Evidence that platelet-reactive autoantibodies can also bind to the mitochondrial antigen M2. J Autoimmun 1990, 3:473-483.
20. Arakawa Y., Amaki S., Miyakawa H., Sakai T., Gotou I., Tanaka N., et al. PBC-AİH overlap syndrome with concomitant ITP and Hashimoto's disease with positivity for anti-centromere antibody. J Gastroenterol 2004, 39:490-495.
21. Toyoda M., Yokomori H., Kaneko F., Yoshida H., Hoshi K., Takeuchi H., et al. Primary biliary cirrhosis - Autoimmune hepatitis overlap syndrome concomitant with sistemic sclerosis, immune thrombocytopenic purpura. Inter Med 2009, 48:2019-2023.
22. Kurihara Y., Shishido T., Oku K., Takamatsu M., Ishiguro H., Suzuki A., et al. Polymyositis associated with autoimmune hepatitis, primary biliary cirrhosis, and autoimmune thrombocytopenic purpura. Mod Rheumatol 2011, 21:325-329.
23. Onishi S., Sakamaki T., Maeda T., Iwamura S., Tomita A., et al. DNA typing of HLA class II genes; DRB1 increases the suspectibility of Japanese to primary biliary cirhosis. J Hepatol 1994, 21:1053-1060.
24. Coss A.E., Granodos J., Uribe M., Torre A. Does HLA-DR7 differentiate the overlap syndrome of autoimmune hepatitis-primary biliary cirrhosis (AIH-PBC) from those with autoimmune hepatitis type 1?. Ann Hepatol 2011, 10(1):28-32.
25. Güzelbulut F., Sezikli M., Akkan-çetinkaya Z., Yaşar B., Özkara S., Kurdaş-övünç A.O. AST-platelet ratio index in the prediction of significant fibrosis and cirrhosis in patients with chronic hepatitis B. Turk J Gastroenterol 2012, 23(4):353-358.
26. Koseoglu M., Hur A., Atay A., Cuhadar S. Effects of hemolysis interferences on routine biochemistry parameters. Biochem Med 2011, 21:79-85.