Repeated haloperidol administration has no effect on vitamin D signaling but increase retinoid X receptors and Nur77 expression in rat prefrontal cortex

Cellular and Molecular Neurobiology

Volumn 33, Issue 3, 2013, Pages 309-312

  Jiang, Pei ^a,b   Zhang, Wen Yuan ^a   Li, Huan De ^a,b   Cai, Hua Lin ^a   Xue, Ying ^b  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Haloperidol; Nur77; Retinoid X receptor; Vitamin D

Indexed keywords

CALCITRIOL; CHOLESTANETRIOL 26 MONOOXYGENASE; CYTOCHROME P450; CYTOCHROME P450 27B1; HALOPERIDOL; NUCLEAR RECEPTOR NUR77; RETINOID X RECEPTOR; UNCLASSIFIED DRUG; VITAMIN D;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; KIDNEY METABOLISM; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SCHIZOPHRENIA; TREATMENT DURATION; VITAMIN BLOOD LEVEL; VITAMIN METABOLISM;

ANIMALS; GENE EXPRESSION REGULATION; HALOPERIDOL; INJECTIONS, INTRAPERITONEAL; KIDNEY; MALE; NUCLEAR RECEPTOR SUBFAMILY 4, GROUP A, MEMBER 1; PREFRONTAL CORTEX; RATS; RATS, SPRAGUE-DAWLEY; RETINOID X RECEPTORS; SIGNAL TRANSDUCTION; VITAMIN D;

RATTUS;

EID: 84876673939     PISSN: 02724340     EISSN: 15736830     Source Type: Journal    
DOI: 10.1007/s10571-012-9902-7     Document Type: Article

References (15)

1. Bouillon R, Carmeliet G, Verlinden L, van Etten E, Verstuyf A, Luderer HF, Lieben L, Mathieu C, Demay M (2008) Vitamin D and human health: lessons from vitamin D receptor null mice. Endocr Rev 29(6):726-776
2. Dawson MI, Xia MI (2012) The retinoid X receptors and their ligands. Biochim Biophys Acta 1821(1):21-56
3. Ethier I, Kagechika H, Shudo K, Rouillard C, Levesque D (2004) Docosahexaenoic acid reduces haloperidol-induced dyskinesias in mice: involvement of Nur77 and retinoid receptors. Biol Psychiatry 56(7):522-526
4. Eyles DW, Burne TH, McGrath JJ (2012) Vitamin D, effects on brain development, adult brain function and the links between low levels of vitamin D and neuropsychiatric disease. Front Neuroendocrinol. doi: 10.1016/j.yfrne.2012. 07.001
5. Fatemi SH, Folsom TD, Reutiman TJ, Novak J, Engel RH (2012) Comparative gene expression study of the chronic exposure to clozapine and haloperidol in rat frontal cortex. Schizophr Res 134(2-3):211-218
6. Harms LR, Burne TH, Eyles DW, McGrath JJ (2011) Vitamin D and the brain. Best Pract Res Clin Endocrinol Metab 25(4):657-669
7. Humble MB, Gustafsson S, Bejerot S (2010) Low serum levels of 25-hydroxyvitamin D (25-OHD) among psychiatric out-patients in Sweden: relations with season, age, ethnic origin and psychiatric diagnosis. J Steroid Biochem Mol Biol 121(1-2):467-470
8. Kesby JP, Cui X, O'Loan J, McGrath JJ, Burne TH, Eyles DW (2010) Developmental vitamin D deficiency alters dopamine-mediated behaviors and dopamine transporter function in adult female rats. Psychopharmacology (Berl) 208(1):159-168
9. Krzyzosiak A, Szyszka-Niagolov M, Wietrzych M, Gobaille S, Muramatsu S, Krezel W (2010) Retinoid x receptor gamma control of affective behaviors involves dopaminergic signaling in mice. Neuron 66(6):908-920
10. Levesque D, Rouillard C (2007) Nur77 and retinoid X receptors: crucial factors in dopamine-related neuroadaptation. Trends Neurosci 30(1):22-30
11. Maheux J, Ethier I, Rouillard C, Levesque D (2005) Induction patterns of transcription factors of the nur family (nurr1, nur77, and nor-1) by typical and atypical antipsychotics in the mouse brain: implication for their mechanism of action. J Pharmacol Exp Ther 313(1):460-473
12. Newmark HL, Newmark J (2007) Vitamin D and Parkinson's disease-a hypothesis. Mov Disord 22(4):461-468
13. Rey-Sanchez P, Lavado-Garcia JM, Canal-Macias ML, Gomez-Zubeldia MA, Roncero-Martin R, Pedrera-Zamorano JD (2009) Ultrasound bone mass in schizophrenic patients on antipsychotic therapy. Hum Psychopharmacol 24(1):49-54
14. Schuster I (2011) Cytochromes P450 are essential players in the vitamin D signaling system. Biochim Biophys Acta 1814(1):186-199
15. Tekes K, Gyenge M, Folyovich A, Csaba G (2009) Influence of neonatal vitamin A or vitamin D treatment on the concentration of biogenic amines and their metabolites in the adult rat brain. Horm Metab Res 41(4):277-280