Paediatric community-acquired septic shock: Results from the REPEM network study

European Journal of Pediatrics

Volumn 172, Issue 5, 2013, Pages 667-674

  Van De Voorde, P ^a   Emerson, B ^b   Gomez, B ^c   Willems, J ^a   Yildizdas, D ^d   Iglowstein, I ^e   Kerkhof, E ^f   Mullen, N ^g   Pinto, C R ^h   Detaille, T ⁱ   Qureshi, N ^j   Naud, J ^k   De Dooy, J ^l   Van Lancker, R ^m   Dupont, A ⁿ   Boelsma, N ^o   Mor, M ^p   Walker, D ^b   Sabbe, M ^m   Hachimi Idrissi, S ^a,o   Da Dalt, L ^q   Waisman, H ^p   Biarent, D ⁿ   MacOnochie, I ^g   Moll, H ^f   Benito, J ^c   more..

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b YALE NEW HAVEN CHILDREN S HOSPITAL   (United States)

^c HOSPITAL DE CRUCES   (Spain)

^d CUKUROVA UNIVERSITY   (Turkey)

^e Ostschweizer Children's Hospital   (Switzerland)

^f SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^g ST MARY S HOSPITAL   (United Kingdom)

^h CENTRO HOSPITALAR E UNIVERSITÁRIO DE COIMBRA   (Portugal)

ⁱ UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^j KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

^k University Hospital   (France)

^l ANTWERP UNIVERSITY HOSPITAL   (Belgium)

^m UNIVERSITY HOSPITALS LEUVEN   (Belgium)

ⁿ HOP UNIV DES ENFANTS REINE FABIOLA   (Belgium)

^o UNIVERSITY HOSPITAL BRUSSELS   (Belgium)

^p SCHNEIDER CHILDREN S MEDICAL CENTER OF ISRAEL   (Israel)

^q CA FONCELLO HOSPITAL   (Italy)

more..

Author keywords

Child; Emergency medicine; Outcome; Paediatric; Sepsis; Shock

Indexed keywords

CORTICOSTEROID; DOBUTAMINE; IMMUNOGLOBULIN; LACTIC ACID;

ANTIBIOTIC THERAPY; ARTICLE; ARTIFICIAL VENTILATION; CHILD; CHILDHOOD MORTALITY; COMMUNITY ACQUIRED SEPTIC SHOCK; COMORBIDITY; DISEASE PREDISPOSITION; DISEASE SEVERITY; EMERGENCY WARD; FEASIBILITY STUDY; FEMALE; HUMAN; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MENINGITIS; PERFUSION; PNEUMONIA; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SEPTIC SHOCK; SURVIVAL; TREATMENT DURATION; TREATMENT OUTCOME;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; COMMUNITY-ACQUIRED INFECTIONS; COMORBIDITY; EMERGENCY SERVICE, HOSPITAL; FEMALE; HOSPITAL MORTALITY; HUMANS; INFANT; LENGTH OF STAY; MALE; PROGNOSIS; RETROSPECTIVE STUDIES; SHOCK, SEPTIC; TREATMENT OUTCOME;

EID: 84876669831     PISSN: 03406199     EISSN: 14321076     Source Type: Journal    
DOI: 10.1007/s00431-013-1930-x     Document Type: Article

References (25)

1. Becker JU, Theodosis C, Jacob ST, Wira CR, Groce NE (2009) Surviving sepsis in low-income and middle-income countries: new directions for care and research. Lancet Infect Dis 9:577-582
2. Brierley J, Carcillo JA, Choong K et al (2009) Clinical practice parameters for hemodynamic support of pediatric and neonatal septic shock: 2007 update from the American College of Critical Care Medicine. Crit Care Med 37:666-688
3. Cruz AT, Perry AM, Williams EA et al (2011) Implementation of goal-directed therapy for children with suspected sepsis in the emergency department. Pediatrics 127:e758-e766
4. de Oliveira CF, de Oliveira DS, Gottschald AF et al (2008) ACCM/PALS haemodynamic support guidelines for paediatric septic shock: an outcomes comparison with and without monitoring central venous oxygen saturation. Int Care Med 34:1065-1075
5. Fiser DH (1992) Assessing the outcome of pediatric intensive care. J Pediatr 121:68-74
6. Fisher JD, Nelson DG, Beyersdorf H (2010) Clinical spectrum of shock in the Pediatric Emergnecy Department. Ped Em Care 26:622-625
7. Goldstein B, Giroir B, Randolph A, Members of the international consensus conference panel (2005) International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics. Pediatr Crit Care Med 6:2-8
8. Herrero M, Alcalde M, Gomez B et al (2012) Invasive bacterial infections in a paediatric emergency department in the era of the heptavalent pneumococcal conjugate vaccine. Eur J Em Med 19:89-94
9. Inwald DP, Tasker RC, Peters MJ, Nadel, PICS Study Group (2009) Emergency management of children with severe sepsis in the United Kingdom: the results of the Paediatric Intensive Care Society sepsis audit. Arch Dis Child 94:348-353
10. Klein Klouwenberg PMC, Ong DSY, Bonten MJC, Cremer OL (2012) Classification of sepsis, severe sepsis and septic shock: the impact of minor variations in data capture and definition of SIRS criteria. Intensive Care Med 38:811-819
11. Larsen GY, Mecham N, Greenberg R (2011) An emergency department septic shock protocol and care guideline for children initiated at triage. Pediatrics 127:e1585-e1592
12. Maitland K, Kiguli S, Opoka RO et al (2011) Mortality after fluid bolus in African children with severe infection. N Engl J Med 364:2483-2495
13. Miettinen OS, Nurminen M (1985) Comparative analysis of two rates. Stat Med 4:213-2
14. Ninis N, Phillips C, Bailey L et al (2005) The role of healthcare delivery in the outcome of meningococcal disease in children: case-control study of fatal and non-fatal cases. BMJ 330:1475-1481
15. Opal SM (2005) Concept of PIRO as a new conceptual framework to understand sepsis. Pediatr Crit Care Med 6(3 suppl):555-560
16. Paul M, Shani V, Muchtar E et al (2010) Systematic review and meta-analysis of the efficacy of appropriate empiric antibiotic therapy for sepsis. Antimicrob Agents Chemother 54:4851-4863
17. Peduzzi P, Concato J, Kemper E, Holford TR, Feinstein AR (1996) A simulation study of the number of events per variable in logistic regression analysis. J Clin Epid 49:1373-1379
18. Rivers PE (2010) Point: adherence to early goal-directed therapy: does it really matter? Yes. After a decade the scientific proof speaks for itself. Chest 138:476-480
19. SNAP 8.0 professional campus edition. Mercator Ltd., Bristol UK. © 2004
20. StatsDirect statistical software, version 2.7.8. StatsDirect Ltd. ©1990-2010
21. Stroud MH, Prodhan P, Moss MM, Anand KJ (2008) Redefining the golden hour in pediatric transport. Pediatr Crit Care Med 9:435-437
22. Vincent JL (2010) We should abandon randomized controlled trials in the intensive care unit. Crit Care Med 38(suppl):S534-S538
23. Watson SR, Carcillo JA, Linde-Zwirble WT et al (2003) The epidemiology of severe sepsis in children in the United States. Am J Respir Crit Care Med 167:695-701
24. Weiss SL, Parker B, Bullock ME et al (2012) Defining pediatric sepsis by different criteria: discrepancies in populations and implications for clinical practice. Pediatr Crit Care Med 13:e219-e226
25. Wolfler A, Silvani P, Musicco M et al (2008) Incidence of and mortality due to sepsis, severe sepsis and septic shock in Italian pediatric intensive care units: a prospective national survey. Int Care Med 34:1690-1697