-
1
-
-
44149090296
-
Role of platelet-derived growth factors in physiology and medicine
-
J. Andrae, R. Gallini, and C. Betsholtz Role of platelet-derived growth factors in physiology and medicine Genes Dev 22 2008 1276 1312
-
(2008)
Genes Dev
, vol.22
, pp. 1276-1312
-
-
Andrae, J.1
Gallini, R.2
Betsholtz, C.3
-
2
-
-
0028589148
-
Platelet-derived growth factor receptor signals
-
L. Claesson-Welsh Platelet-derived growth factor receptor signals J Biol Chem 269 1994 32023 32026
-
(1994)
J Biol Chem
, vol.269
, pp. 32023-32026
-
-
Claesson-Welsh, L.1
-
3
-
-
0142243109
-
Roles of PDGF in animal development
-
R.V. Hoch, and P. Soriano Roles of PDGF in animal development Development 130 2003 4769 4784
-
(2003)
Development
, vol.130
, pp. 4769-4784
-
-
Hoch, R.V.1
Soriano, P.2
-
4
-
-
0032547385
-
Signal transduction via platelet-derived growth factor receptors
-
C.H. Heldin, A. Ostman, and L. Ronnstrand Signal transduction via platelet-derived growth factor receptors Biochim Biophys Acta 1378 1998 F79 F113
-
(1998)
Biochim Biophys Acta
, vol.1378
-
-
Heldin, C.H.1
Ostman, A.2
Ronnstrand, L.3
-
5
-
-
0029079275
-
The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
-
T.F. Franke, S.I. Yang, T.O. Chan, K. Datta, A. Kazlauskas, D.K. Morrison, D.R. Kaplan, and P.N. Tsichlis The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase Cell 81 1995 727 736
-
(1995)
Cell
, vol.81
, pp. 727-736
-
-
Franke, T.F.1
Yang, S.I.2
Chan, T.O.3
Datta, K.4
Kazlauskas, A.5
Morrison, D.K.6
Kaplan, D.R.7
Tsichlis, P.N.8
-
6
-
-
0032875460
-
Mechanism of action and in vivo role of platelet-derived growth factor
-
C.H. Heldin, and B. Westermark Mechanism of action and in vivo role of platelet-derived growth factor Physiol Rev 79 1999 1283 1316
-
(1999)
Physiol Rev
, vol.79
, pp. 1283-1316
-
-
Heldin, C.H.1
Westermark, B.2
-
7
-
-
57049093954
-
Comprehensive dissection of PDGF-PDGFR signaling pathways in PDGFR genetically defined cells
-
E. Wu, N. Palmer, Z. Tian, A.P. Moseman, M. Galdzicki, X. Wang, B. Berger, H. Zhang, and I.S. Kohane Comprehensive dissection of PDGF-PDGFR signaling pathways in PDGFR genetically defined cells PLoS One 3 2008 e3794
-
(2008)
PLoS One
, vol.3
, pp. 3794
-
-
Wu, E.1
Palmer, N.2
Tian, Z.3
Moseman, A.P.4
Galdzicki, M.5
Wang, X.6
Berger, B.7
Zhang, H.8
Kohane, I.S.9
-
8
-
-
34447326697
-
Platelet-derived growth factor receptor-alpha: A novel therapeutic target in human hepatocellular cancer
-
P. Stock, D. Monga, X. Tan, A. Micsenyi, N. Loizos, and S.P. Monga Platelet-derived growth factor receptor-alpha: a novel therapeutic target in human hepatocellular cancer Mol Cancer Ther 6 2007 1932 1941
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1932-1941
-
-
Stock, P.1
Monga, D.2
Tan, X.3
Micsenyi, A.4
Loizos, N.5
Monga, S.P.6
-
9
-
-
67649219059
-
PDGFRalpha: A new therapeutic target in the treatment of hepatocellular carcinoma?
-
A.M. Oseini, and L.R. Roberts PDGFRalpha: a new therapeutic target in the treatment of hepatocellular carcinoma? Expert Opin Ther Targets 13 2009 443 454
-
(2009)
Expert Opin Ther Targets
, vol.13
, pp. 443-454
-
-
Oseini, A.M.1
Roberts, L.R.2
-
10
-
-
76249102739
-
Organogenesis and development of the liver
-
K. Si-Tayeb, F.P. Lemaigre, and S.A. Duncan Organogenesis and development of the liver Dev Cell 18 2010 175 189
-
(2010)
Dev Cell
, vol.18
, pp. 175-189
-
-
Si-Tayeb, K.1
Lemaigre, F.P.2
Duncan, S.A.3
-
13
-
-
0037220834
-
Beta-catenin antisense studies in embryonic liver cultures: Role in proliferation, apoptosis, and lineage specification
-
S.P. Monga, H.K. Monga, X. Tan, K. Mule, P. Pediaditakis, and G.K. Michalopoulos Beta-catenin antisense studies in embryonic liver cultures: role in proliferation, apoptosis, and lineage specification Gastroenterology 124 2003 202 216
-
(2003)
Gastroenterology
, vol.124
, pp. 202-216
-
-
Monga, S.P.1
Monga, H.K.2
Tan, X.3
Mule, K.4
Pediaditakis, P.5
Michalopoulos, G.K.6
-
14
-
-
0035079328
-
Expansion of hepatic and hematopoietic stem cells utilizing mouse embryonic liver explants
-
S.P. Monga, Y. Tang, F. Candotti, A. Rashid, O. Wildner, B. Mishra, S. Iqbal, and L. Mishra Expansion of hepatic and hematopoietic stem cells utilizing mouse embryonic liver explants Cell Transplant 10 2001 81 89
-
(2001)
Cell Transplant
, vol.10
, pp. 81-89
-
-
Monga, S.P.1
Tang, Y.2
Candotti, F.3
Rashid, A.4
Wildner, O.5
Mishra, B.6
Iqbal, S.7
Mishra, L.8
-
15
-
-
84869214376
-
Stromal platelet-derived growth factor receptor alpha (PDGFRalpha) provides a therapeutic target independent of tumor cell PDGFRalpha expression in lung cancer xenografts
-
D.E. Gerber, P. Gupta, M.T. Dellinger, J.E. Toombs, M. Peyton, I. Duignan, J. Malaby, T. Bailey, C. Burns, R.A. Brekken, and N. Loizos Stromal platelet-derived growth factor receptor alpha (PDGFRalpha) provides a therapeutic target independent of tumor cell PDGFRalpha expression in lung cancer xenografts Mol Cancer Ther 11 2012 2473 2482
-
(2012)
Mol Cancer Ther
, vol.11
, pp. 2473-2482
-
-
Gerber, D.E.1
Gupta, P.2
Dellinger, M.T.3
Toombs, J.E.4
Peyton, M.5
Duignan, I.6
Malaby, J.7
Bailey, T.8
Burns, C.9
Brekken, R.A.10
Loizos, N.11
-
16
-
-
0037323832
-
Cell autonomous requirement for PDGFRalpha in populations of cranial and cardiac neural crest cells
-
M.D. Tallquist, and P. Soriano Cell autonomous requirement for PDGFRalpha in populations of cranial and cardiac neural crest cells Development 130 2003 507 518
-
(2003)
Development
, vol.130
, pp. 507-518
-
-
Tallquist, M.D.1
Soriano, P.2
-
17
-
-
0034059141
-
DNA excision in liver by an albumin-Cre transgene occurs progressively with age
-
C. Postic, and M.A. Magnuson DNA excision in liver by an albumin-Cre transgene occurs progressively with age Genesis 26 2000 149 150
-
(2000)
Genesis
, vol.26
, pp. 149-150
-
-
Postic, C.1
Magnuson, M.A.2
-
18
-
-
77951487860
-
Accelerated liver regeneration and hepatocarcinogenesis in mice overexpressing serine-45 mutant beta-catenin
-
K.N. Nejak-Bowen, M.D. Thompson, S. Singh, W.C. Bowen Jr., M.J. Dar, J. Khillan, C. Dai, and S.P. Monga Accelerated liver regeneration and hepatocarcinogenesis in mice overexpressing serine-45 mutant beta-catenin Hepatology 51 2010 1603 1613
-
(2010)
Hepatology
, vol.51
, pp. 1603-1613
-
-
Nejak-Bowen, K.N.1
Thompson, M.D.2
Singh, S.3
Bowen Jr., W.C.4
Dar, M.J.5
Khillan, J.6
Dai, C.7
Monga, S.P.8
-
19
-
-
33750726092
-
Conditional deletion of beta-catenin reveals its role in liver growth and regeneration
-
X. Tan, J. Behari, B. Cieply, G.K. Michalopoulos, and S.P. Monga Conditional deletion of beta-catenin reveals its role in liver growth and regeneration Gastroenterology 131 2006 1561 1572
-
(2006)
Gastroenterology
, vol.131
, pp. 1561-1572
-
-
Tan, X.1
Behari, J.2
Cieply, B.3
Michalopoulos, G.K.4
Monga, S.P.5
-
20
-
-
0031017151
-
Selective bipotential differentiation of mouse embryonic hepatoblasts in vitro
-
L.E. Rogler Selective bipotential differentiation of mouse embryonic hepatoblasts in vitro Am J Pathol 150 1997 591 602
-
(1997)
Am J Pathol
, vol.150
, pp. 591-602
-
-
Rogler, L.E.1
-
22
-
-
0038757830
-
Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis
-
F. Parviz, C. Matullo, W.D. Garrison, L. Savatski, J.W. Adamson, G. Ning, K.H. Kaestner, J.M. Rossi, K.S. Zaret, and S.A. Duncan Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis Nat Genet 34 2003 292 296
-
(2003)
Nat Genet
, vol.34
, pp. 292-296
-
-
Parviz, F.1
Matullo, C.2
Garrison, W.D.3
Savatski, L.4
Adamson, J.W.5
Ning, G.6
Kaestner, K.H.7
Rossi, J.M.8
Zaret, K.S.9
Duncan, S.A.10
-
23
-
-
63349109309
-
Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development
-
K. Asahina, S.Y. Tsai, P. Li, M. Ishii, R.E. Maxson Jr., H.M. Sucov, and H. Tsukamoto Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development Hepatology 49 2009 998 1011
-
(2009)
Hepatology
, vol.49
, pp. 998-1011
-
-
Asahina, K.1
Tsai, S.Y.2
Li, P.3
Ishii, M.4
Maxson Jr., R.E.5
Sucov, H.M.6
Tsukamoto, H.7
-
24
-
-
33750348542
-
Platelet derived growth factor receptor alpha is essential for establishing a microenvironment that supports definitive erythropoiesis
-
W.L. Li, Y. Yamada, M. Ueno, S. Nishikawa, and N. Takakura Platelet derived growth factor receptor alpha is essential for establishing a microenvironment that supports definitive erythropoiesis J Biochem 140 2006 267 273
-
(2006)
J Biochem
, vol.140
, pp. 267-273
-
-
Li, W.L.1
Yamada, Y.2
Ueno, M.3
Nishikawa, S.4
Takakura, N.5
-
25
-
-
0034951680
-
Smad proteins and hepatocyte growth factor control parallel regulatory pathways that converge on beta1-integrin to promote normal liver development
-
M. Weinstein, S.P. Monga, Y. Liu, S.G. Brodie, Y. Tang, C. Li, L. Mishra, and C.X. Deng Smad proteins and hepatocyte growth factor control parallel regulatory pathways that converge on beta1-integrin to promote normal liver development Mol Cell Biol 21 2001 5122 5131
-
(2001)
Mol Cell Biol
, vol.21
, pp. 5122-5131
-
-
Weinstein, M.1
Monga, S.P.2
Liu, Y.3
Brodie, S.G.4
Tang, Y.5
Li, C.6
Mishra, L.7
Deng, C.X.8
-
26
-
-
33745034466
-
Concerted functions of Gab1 and Shp2 in liver regeneration and hepatoprotection
-
E.A. Bard-Chapeau, J. Yuan, N. Droin, S. Long, E.E. Zhang, T.V. Nguyen, and G.S. Feng Concerted functions of Gab1 and Shp2 in liver regeneration and hepatoprotection Mol Cell Biol 26 2006 4664 4674
-
(2006)
Mol Cell Biol
, vol.26
, pp. 4664-4674
-
-
Bard-Chapeau, E.A.1
Yuan, J.2
Droin, N.3
Long, S.4
Zhang, E.E.5
Nguyen, T.V.6
Feng, G.S.7
-
27
-
-
3242663197
-
Met provides essential signals for liver regeneration
-
M. Borowiak, A.N. Garratt, T. Wustefeld, M. Strehle, C. Trautwein, and C. Birchmeier Met provides essential signals for liver regeneration Proc Natl Acad Sci U S A 101 2004 10608 10613
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 10608-10613
-
-
Borowiak, M.1
Garratt, A.N.2
Wustefeld, T.3
Strehle, M.4
Trautwein, C.5
Birchmeier, C.6
-
28
-
-
77949825509
-
Characterization and functional analyses of hepatic mesothelial cells in mouse liver development
-
1535.e1521-1526
-
I. Onitsuka, M. Tanaka, and A. Miyajima Characterization and functional analyses of hepatic mesothelial cells in mouse liver development Gastroenterology 138 2010 1525 1535 1535.e1521-1526
-
(2010)
Gastroenterology
, vol.138
, pp. 1525-1535
-
-
Onitsuka, I.1
Tanaka, M.2
Miyajima, A.3
-
29
-
-
34250312451
-
Cell cycle effects resulting from inhibition of hepatocyte growth factor and its receptor c-Met in regenerating rat livers by RNA interference
-
S. Paranjpe, W.C. Bowen, A.W. Bell, K. Nejak-Bowen, J.H. Luo, and G.K. Michalopoulos Cell cycle effects resulting from inhibition of hepatocyte growth factor and its receptor c-Met in regenerating rat livers by RNA interference Hepatology 45 2007 1471 1477
-
(2007)
Hepatology
, vol.45
, pp. 1471-1477
-
-
Paranjpe, S.1
Bowen, W.C.2
Bell, A.W.3
Nejak-Bowen, K.4
Luo, J.H.5
Michalopoulos, G.K.6
-
30
-
-
77953202698
-
RNA interference against hepatic epidermal growth factor receptor has suppressive effects on liver regeneration in rats
-
S. Paranjpe, W.C. Bowen, G.C. Tseng, J.H. Luo, A. Orr, and G.K. Michalopoulos RNA interference against hepatic epidermal growth factor receptor has suppressive effects on liver regeneration in rats Am J Pathol 176 2010 2669 2681
-
(2010)
Am J Pathol
, vol.176
, pp. 2669-2681
-
-
Paranjpe, S.1
Bowen, W.C.2
Tseng, G.C.3
Luo, J.H.4
Orr, A.5
Michalopoulos, G.K.6
-
31
-
-
78651447817
-
Liver regeneration: Alternative epithelial pathways
-
G.K. Michalopoulos Liver regeneration: alternative epithelial pathways Int J Biochem Cell Biol 43 2011 173 179
-
(2011)
Int J Biochem Cell Biol
, vol.43
, pp. 173-179
-
-
Michalopoulos, G.K.1
-
32
-
-
0034989658
-
Developmental roles of platelet-derived growth factors
-
C. Betsholtz, L. Karlsson, and P. Lindahl Developmental roles of platelet-derived growth factors Bioessays 23 2001 494 507
-
(2001)
Bioessays
, vol.23
, pp. 494-507
-
-
Betsholtz, C.1
Karlsson, L.2
Lindahl, P.3
-
33
-
-
0032549537
-
The epidermal growth factor receptor associates with and recruits phosphatidylinositol 3-kinase to the platelet-derived growth factor beta receptor
-
A.A. Habib, T. Hognason, J. Ren, K. Stefansson, and R.R. Ratan The epidermal growth factor receptor associates with and recruits phosphatidylinositol 3-kinase to the platelet-derived growth factor beta receptor J Biol Chem 273 1998 6885 6891
-
(1998)
J Biol Chem
, vol.273
, pp. 6885-6891
-
-
Habib, A.A.1
Hognason, T.2
Ren, J.3
Stefansson, K.4
Ratan, R.R.5
-
34
-
-
0034805908
-
Receptor heterodimerization: Essential mechanism for platelet-derived growth factor-induced epidermal growth factor receptor transactivation
-
Y. Saito, J. Haendeler, Y. Hojo, K. Yamamoto, and B.C. Berk Receptor heterodimerization: essential mechanism for platelet-derived growth factor-induced epidermal growth factor receptor transactivation Mol Cell Biol 21 2001 6387 6394
-
(2001)
Mol Cell Biol
, vol.21
, pp. 6387-6394
-
-
Saito, Y.1
Haendeler, J.2
Hojo, Y.3
Yamamoto, K.4
Berk, B.C.5
-
35
-
-
79955433548
-
Targeted therapies for hepatocellular carcinoma
-
A. Villanueva, and J.M. Llovet Targeted therapies for hepatocellular carcinoma Gastroenterology 140 2011 1410 1426
-
(2011)
Gastroenterology
, vol.140
, pp. 1410-1426
-
-
Villanueva, A.1
Llovet, J.M.2
-
36
-
-
33747830764
-
Hepatocellular carcinoma pathogenesis: From genes to environment
-
P.A. Farazi, and R.A. DePinho Hepatocellular carcinoma pathogenesis: from genes to environment Nat Rev Cancer 6 2006 674 687
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 674-687
-
-
Farazi, P.A.1
Depinho, R.A.2
-
37
-
-
36048986396
-
Targeting stromal cells for the treatment of platelet-derived growth factor C-induced hepatocellular carcinogenesis
-
J.S. Campbell, M.M. Johnson, R.L. Bauer, K.L. Hudkins, D.G. Gilbertson, K.J. Riehle, M.M. Yeh, C.E. Alpers, and N. Fausto Targeting stromal cells for the treatment of platelet-derived growth factor C-induced hepatocellular carcinogenesis Differentiation 75 2007 843 852
-
(2007)
Differentiation
, vol.75
, pp. 843-852
-
-
Campbell, J.S.1
Johnson, M.M.2
Bauer, R.L.3
Hudkins, K.L.4
Gilbertson, D.G.5
Riehle, K.J.6
Yeh, M.M.7
Alpers, C.E.8
Fausto, N.9
-
38
-
-
20144389471
-
Targeting the platelet-derived growth factor receptor alpha with a neutralizing human monoclonal antibody inhibits the growth of tumor xenografts: Implications as a potential therapeutic target
-
N. Loizos, Y. Xu, J. Huber, M. Liu, D. Lu, B. Finnerty, R. Rolser, A. Malikzay, A. Persaud, E. Corcoran, D.S. Deevi, P. Balderes, R. Bassi, X. Jimenez, C.J. Joynes, V.R. Mangalampalli, P. Steiner, J.R. Tonra, Y. Wu, D.S. Pereira, Z. Zhu, D.L. Ludwig, D.J. Hicklin, P. Bohlen, L. Witte, and P. Kussie Targeting the platelet-derived growth factor receptor alpha with a neutralizing human monoclonal antibody inhibits the growth of tumor xenografts: implications as a potential therapeutic target Mol Cancer Ther 4 2005 369 379
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 369-379
-
-
Loizos, N.1
Xu, Y.2
Huber, J.3
Liu, M.4
Lu, D.5
Finnerty, B.6
Rolser, R.7
Malikzay, A.8
Persaud, A.9
Corcoran, E.10
Deevi, D.S.11
Balderes, P.12
Bassi, R.13
Jimenez, X.14
Joynes, C.J.15
Mangalampalli, V.R.16
Steiner, P.17
Tonra, J.R.18
Wu, Y.19
Pereira, D.S.20
Zhu, Z.21
Ludwig, D.L.22
Hicklin, D.J.23
Bohlen, P.24
Witte, L.25
Kussie, P.26
more..
-
39
-
-
76249126427
-
Rationale for the development of IMC-3G3, a fully human immunoglobulin G subclass 1 monoclonal antibody targeting the platelet-derived growth factor receptor alpha
-
G.D. Shah, N. Loizos, H. Youssoufian, J.D. Schwartz, and E.K. Rowinsky Rationale for the development of IMC-3G3, a fully human immunoglobulin G subclass 1 monoclonal antibody targeting the platelet-derived growth factor receptor alpha Cancer 116 2010 1018 1026
-
(2010)
Cancer
, vol.116
, pp. 1018-1026
-
-
Shah, G.D.1
Loizos, N.2
Youssoufian, H.3
Schwartz, J.D.4
Rowinsky, E.K.5
|