High-inspired oxygen concentration further impairs opioid-induced respiratory depression

British Journal of Anaesthesia

Volumn 110, Issue 5, 2013, Pages 837-841

  Niesters, M ^a   Mahajan, R P ^b   Aarts, L ^a   Dahan, A ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

analgesics; hyperoxia; hypoventilation; hypoxia; monitoring; opioids; oxygen; remifentanil; respiration; respiratory depression; respiratory rate; ventilatory depression

Indexed keywords

OPIATE; OXYGEN; REMIFENTANIL;

ADULT; AMBIENT AIR; APNEA; ARTICLE; BREATHING RATE; CARBON DIOXIDE TENSION; CLINICAL ARTICLE; FEMALE; HUMAN; HYPEROXIA; LUNG MINUTE VOLUME; MALE; NORMAL HUMAN; OXYGEN CONCENTRATION; PRIORITY JOURNAL; RESPIRATION DEPRESSION;

EID: 84876563301     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aes494     Document Type: Article

References (19)

1. Dahan A, Aarts L, Smith TW. Incidence, reversal and prevention of opioid-induced respiratory depression. Anesthesiology 2010; 112: 226-38
2. Dahan A, DeGoede J, Berkenbosch A, Olievier I. The influence of oxygen on the ventilatory response to carbon dioxide in man. J Physiol (Lond) 1990; 428: 485-99
3. Lambertsen CJ, Hall P, Wollman H, Goodman MW. Quantitative interactions of increased PO2 and PCO2 upon respiration in man. Ann N Y Acad Sci 1963; 109: 731-42
4. Pattinson KT. Opioids and the control of respiration. Br J Anaesth 2008; 100: 747-58
5. Douma MR, Middeldorp JM, Verwey RA, Dahan A, Stienstra R. A randomised comparison of intravenous remifentanil patientcontrolled analgesia with epidural ropivacaine/sufentanil during labour. Int J Obstet Anesth 2011; 20: 118-23
6. Atkins JH, Mandel JE, Mirza N. Laser ablation of a large tongue hemangioma with remifentanil analgosedation in the ORL endoscopy suite. ORL J Otorhinolaryngol Relat Spec 2011; 73: 166-9
7. Lipszyc L, Winters E, Engelman E, Baurain M, Barvais L. Remifentanil patient-controlled analgesia effect-site target-controlled infusion compared with morphine patient-controlled analgesia for treatment of acute pain after uterine artery embolization. Br J Anaesth 2011; 106: 724-31
8. Nieuwenhuijs D, Olofsen E, Romberg R, et al. Response surface modeling of remifentanil-propofol interaction on cardiorespiratory control and bispectral index. Anesthesiology 2003; 98: 313-22
9. Gozal D. Potentiation of hypoxic ventilatory response by hyperoxia in the conscious rat: putative role of nitric oxide. J Appl Physiol 1998; 85: 129-32
10. Pokorski M, Kolesnikova E, Marczak M, Budziń ska K. Neurotransmitter mechanisms in the enhancement of the hypoxic ventilatory response by antecedent hyperoxia in the anesthetized rat. J Physiol Pharmacol 2005; 56: 433-46
11. Bernards CM, Knowlton SL, Schmidt DF, et al. Respiratory and sleep effects of remifentanil in volunteers with moderate obstructive sleep apnea. Anesthesiology 2009; 110: 41-9
12. Cornet AD, Kooter AJ, Peters MJ, Smulders YM. Supplemental oxygen therapy in medical emergencies: more harm than benefit? Arch Intern Med 2012; 172: 289-90.
13. Kilgannon JH, Jones AE, Parrillo JE, et al. Relationship between supranormal oxygen tension and outcome after resuscitation from cardiac arrest. Circulation 2011; 123: 2717-22
14. Kuisma M, Boyd J, Voipio V, AlaspääA, Roine RO, Rosenberg P. Comparison of 30 and the 100% inspired oxygen concentrations during early post-resuscitation period: a randomised controlled pilot study. Resuscitation 2006; 69: 199-206
15. Davidson JA, Hosie HE. Limitations of pulse oximetry: respiratory insufficiency-a failure of detection. Br Med J 1993; 307: 372-3
16. Downs JB. Prevention of hypoxemia: the simple, logical, but incorrect solution. J Clin Anesth 1994; 6: 180-1
17. 2 sensitivity. PLoS Med 2007; 4: e239
18. Brown KA, Laferrière A, Lakheeram I, Moss IR. Recurrent hypoxemia in children is associated with increased analgesic sensitivity to opiates. Anesthesiology 2006; 105: 665-9
19. Moss IR, Brown KA, Laferrière A. Recurrent hypoxia in rats during development increases subsequent respiratory sensitivity to fentanyl. Anesthesiology 2006; 105: 715-8