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Volumn 10, Issue 2, 2013, Pages 344-346

Uptake of novel statistical methods for early-phase clinical studies in the UK public sector

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BAYES THEOREM; CLINICAL PRACTICE; CLINICAL TRIAL (TOPIC); COMPUTER PROGRAM; FUNDING; HUMAN; ORGANIZATION AND MANAGEMENT; PRIORITY JOURNAL; QUESTIONNAIRE; STATISTICAL ANALYSIS; UNITED KINGDOM;

EID: 84876557281     PISSN: 17407745     EISSN: 17407753     Source Type: Journal    
DOI: 10.1177/1740774512474375     Document Type: Article
Times cited : (36)

References (11)
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    • Adaptive designs in clinical drug development: Opportunities, challenges, and scope reflections following PhRMA's November 2006 workshop
    • Krams M, Burman C-F, Dragalin V, et al. Adaptive designs in clinical drug development: Opportunities, challenges, and scope reflections following PhRMA's November 2006 workshop. J Biopharm Stat. 2007 ; 17: 957-64
    • (2007) J Biopharm Stat , vol.17 , pp. 957-964
    • Krams, M.1    Burman, C.-F.2    Dragalin, V.3
  • 2
    • 50549174560 scopus 로고
    • The determination of the number of patients required in a preliminary and a follow-up trial of a new chemotherapeutic agent
    • Gehan EA. The determination of the number of patients required in a preliminary and a follow-up trial of a new chemotherapeutic agent. J Chro Dis. 1960 ; 13: 346-53
    • (1960) J Chro Dis , vol.13 , pp. 346-353
    • Gehan, E.A.1
  • 4
    • 0024536437 scopus 로고
    • Optimal two-stage designs for phase II clinical trials
    • Simon R. Optimal two-stage designs for phase II clinical trials. Control Clin Trials. 1989 ; 10: 1-10
    • (1989) Control Clin Trials , vol.10 , pp. 1-10
    • Simon, R.1
  • 5
    • 21844475901 scopus 로고    scopus 로고
    • Flexible Bayesian methods for cancer phase i clinical trials: Dose escalation with overdose control
    • Tighiouart M, Rogatko A, Babb J. Flexible Bayesian methods for cancer phase I clinical trials: Dose escalation with overdose control. Stat Med. 2005 ; 24: 2183-96
    • (2005) Stat Med , vol.24 , pp. 2183-2196
    • Tighiouart, M.1    Rogatko, A.2    Babb, J.3
  • 6
    • 64549124373 scopus 로고    scopus 로고
    • One- and two-stage design proposals for a phase II trial comparing three active treatments with control using an ordered categorical endpoint
    • Whitehead J, Jaki T. One- and two-stage design proposals for a phase II trial comparing three active treatments with control using an ordered categorical endpoint. Stat Med. 2009 ; 28: 828-47
    • (2009) Stat Med , vol.28 , pp. 828-847
    • Whitehead, J.1    Jaki, T.2
  • 7
    • 0025148278 scopus 로고
    • Continual reassessment method: A practical design for phase i clinical trials in cancer
    • O'Quigley J, Pepe M, Fisher L. Continual reassessment method: A practical design for phase I clinical trials in cancer. Biometrics. 1990 ; 46: 33-48
    • (1990) Biometrics , vol.46 , pp. 33-48
    • O'Quigley, J.1    Pepe, M.2    Fisher, L.3
  • 8
    • 36849035490 scopus 로고    scopus 로고
    • Translation of innovative designs into phase i trials
    • Rogatko A, Schoeneck D, Jonas W, et al. Translation of innovative designs into phase I trials. J Clin Oncol. 2007 ; 25: 4982-86
    • (2007) J Clin Oncol , vol.25 , pp. 4982-4986
    • Rogatko, A.1    Schoeneck, D.2    Jonas, W.3
  • 9
    • 66849118694 scopus 로고    scopus 로고
    • Dose escalation methods in phase i cancer trials
    • Le Tourneau C, Lee JJ, Siu LL. Dose escalation methods in phase I cancer trials. J Natl Cancer I. 2009 ; 101: 708-20
    • (2009) J Natl Cancer i , vol.101 , pp. 708-720
    • Le Tourneau, C.1    Lee, J.J.2    Siu, L.L.3
  • 10
    • 85065990548 scopus 로고    scopus 로고
    • Guidance for Industry Draft guidance, February2010. Available at
    • Guidance for Industry. Adaptive design clinical trials for drugs and biologics. Draft guidance, February2010. Available at: www.fda.gov/downloads/ Drugs/GuidanceComplianceRegulatoryInformation/Guidances/UCM201790.pdf
    • Adaptive Design Clinical Trials for Drugs and Biologics


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.