A kinetic framework for tRNA ligase and enforcement of a 2'-phosphate requirement for ligation highlights the design logic of an RNA repair machine

RNA

Volumn 19, Issue 5, 2013, Pages 659-669

  Remus, Barbara S ^a   Shuman, Stewart ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Cyclic phosphodiesterase; Polynucleotide kinase; RNA ligase; RNA quality control; TRNA splicing

Indexed keywords

2',3' CYCLIC PHOSPHODIESTERASE; PHOSPHODIESTERASE; RNA LIGASE; TRNA LIGASE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL REACTION; ENZYME ACTIVITY; ENZYME KINETICS; IN VITRO STUDY; KINETICS; PRIORITY JOURNAL; RNA REPAIR; WILD TYPE;

KINETICS; PHOSPHATES; PHOSPHORIC DIESTER HYDROLASES; PROTEIN STRUCTURE, TERTIARY; RNA; RNA LIGASE (ATP); RNA SPLICING; RNA, TRANSFER; SACCHAROMYCES CEREVISIAE;

EID: 84876555641     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.038406.113     Document Type: Article

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