MRI characterization and longitudinal study of focal cerebellar lesions in a young tuberous sclerosis cohort

American Journal of Neuroradiology

Volumn 34, Issue 3, 2013, Pages 655-659

  Vaughn, J ^a   Hagiwara, M ^a   Katz, J ^a   Roth, J ^b   Devinsky, O ^a   Weiner, H ^a   Milla, S ^a  

^a NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^b TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

GADOLINIUM;

ADOLESCENT; ADULT; ARTICLE; BRAIN CALCIFICATION; CEREBELLUM ATROPHY; CEREBELLUM INJURY; CHILD; CLINICAL ASSESSMENT; COHORT ANALYSIS; CONTRAST ENHANCEMENT; FEMALE; FOLLOW UP; HUMAN; INFANT; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; NEWBORN; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PRESCHOOL CHILD; RETROSPECTIVE STUDY; SCHOOL CHILD; TUBEROUS SCLEROSIS;

CEREBELLAR DISEASES; CEREBELLUM; CHILD; FEMALE; HUMANS; LONGITUDINAL STUDIES; MAGNETIC RESONANCE IMAGING; MALE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TUBEROUS SCLEROSIS;

EID: 84876531421     PISSN: 01956108     EISSN: 1936959X     Source Type: Journal    
DOI: 10.3174/ajnr.A3260     Document Type: Article

References (21)

1. Baskin HJ. The pathogenesis and imaging of the tuberous sclerosis complex. Pediatr Radiol 2008;38:936-52
2. Dabora SL, Jozwiak S, Franz DN, et al. Mutational analysis in a cohort of 224 tuberous sclerosis patients indicates increased severity of TSC2, compared with TSC1, disease in multiple organs. Am J Hum Genet 2001;68:64-80
3. Prather P, de Vries PJ. Behavioral and cognitive aspects of tuberous sclerosis complex. J Child Neurol 2004;19:666-74
4. Eluvathingal TJ, Behen ME, Chugani HT, et al. Cerebellar lesions in tuberous sclerosis complex: neurobehavioral and neuroimaging correlates. J Child Neurol 2006;21:846-51
5. Martí-Bonmatí L, Menor F, Dosdá R. Tuberous sclerosis: differences between cerebral and cerebellar cortical tubers in a pediatric population. AJNR Am J Neuroradiol 2000;21:557-60
6. O'Callaghan FJ, Harris T, Joinson C, et al. The relation of infantile spasms, tubers, and intelligence in tuberous sclerosis complex. Arch Dis Child 2004;89:530-33
7. Ertan G, Arulrajah S, Tekes A, et al. Cerebellar abnormality in children and young adults with tuberous sclerosis complex: MR and diffusion weighted imaging findings. J Neuroradiol 2010;37:231-38
8. Chu-Shore CJ, Frosch MP, Grant PE, et al. Progressive multifocal cystlike cortical tubers in tuberous sclerosis complex: clinical and neuropathologic findings. Epilepsia 2009;50:2648-51
9. Lee A, Maldonado M, Baybis M, et al. Markers of cellular proliferation are expressed in cortical tubers. Ann Neurol 2003;53:668-73
10. Jay V, Edwards V, Musharbash A, et al. Cerebellar pathology in tuberous sclerosis. Ultrastruct Pathol 1998;22:331-39
11. Grajkowska W, Kotulska K, Jurkiewicz E, et al. Brain lesions in tuberous sclerosis complex: review. Folia Neuropathol 2010;48:139-49
12. Castillo M, Whaley RA, Point SW, et al. Gyriform enhancement in tuberous sclerosis simulating infarction. Radiology 1992;185:613-14
13. Chu-Shore CJ, Major P, Montenegro M, et al. Cyst-like tubers are associated with TSC2 and epilepsy in tuberous sclerosis complex. Neurology 2009;72:1165-69
14. Major P, Rakowski S, Simon MV, et al. Are cortical tubers epileptogenic? Evidence from electrocorticography. Epilepsia 2009;50:147-54
15. Menor F, Marti-Bonmati L, Mulas F, et al. Neuroimaging in tuberous sclerosis: a clinicoradiological evaluation in pediatric patients. Pediatr Radiol 1992;22:485-89
16. Weber AM, Egelhoff JC, McKellop JM, et al. Autism and the cerebellum: evidence from tuberous sclerosis. J Autism Dev Disord 2000;30:511-17
17. Asano E, Chugani DC, Muzik O, et al. Autism in tuberous sclerosis complex is related to both cortical and subcortical dysfunction. Neurology 2001;57:1269-77
18. Bolton PF, Griffiths PD. Association of tuberous sclerosis of temporal lobes with autism and atypical autism. Lancet 1997;349:392-95
19. Bolton PF, Park RJ, Higgins NP, et al. Neuro-epileptic determinants of autism spectrum disorders in tuberous sclerosis complex. Brain 2002;125:1247-55
20. Numis AL, Major P, Montenegro MA, et al. Identification of risk factors for autism spectrum disorders in tuberous sclerosis complex. Neurology 2011;76:981
21. Gallagher A, Grant EP, Madan N, et al. MRI findings reveal three different types of tubers in patients with tuberous sclerosis complex. J Neurol 2010;257:1373-81