Subacute combined degeneration of the spinal cord following recreational nitrous oxide use

BMJ Case Reports

Volumn , Issue , 2013, Pages

  Cheng, Hui Mei ^a   Park, Jae Hong ^a   Hernstadt, David ^a  

^a ROYAL PERTH HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CYANOCOBALAMIN; NITROUS OXIDE;

ADULT; ARTICLE; CASE REPORT; CYANOCOBALAMIN DEFICIENCY; DIFFERENTIAL DIAGNOSIS; DRUG ABUSE; FEMALE; GAIT; HUMAN; HYPERREFLEXIA; LIMB WEAKNESS; NUCLEAR MAGNETIC RESONANCE IMAGING; PARESTHESIA; PERIPHERAL NEUROPATHY; PHYSICAL EXAMINATION; PHYSIOTHERAPY; PRIORITY JOURNAL; PROPRIOCEPTION; SKIN TINGLING; SPINAL CORD ATROPHY; SPINAL CORD DISEASE; TOUCH; VIBRATION; VITAMIN BLOOD LEVEL;

EID: 84876523957     PISSN: None     EISSN: 1757790X     Source Type: Journal    
DOI: 10.1136/bcr-2012-008509     Document Type: Article

References (18)

1. Yagiela JA. Health hazards and nitrous oxide: a time for reappraisal. Anesth Prog 1991;38: 1-11.
2. Louis-Ferdinand RT. Myeotoxic, neurotoxic and reproductive adverse effects of nitrous oxide. Adverse Drug React Toxicol Rev 1994;13: 193-206.
3. Graber JJ, Sherman FT, Kaufmann H, et al. Vitamin B12-responsive severe leukoencephalopathy and autonomic dysfunction in a patient with "normal" serum B12 levels. J Neurol Neurosurg Psychiatry 2010;81: 1369-71.
4. Layzer RB, Fishman RA, Schafer JA. Neuropathy following abuse of nitrous oxide. Neurol 1978;28: 504-6.
5. Ilniczky J, Jelencsik I, Kenez J, et al. MR findings in subacute combined degeneration of the spinal cord caused by nitrous oxide anaesthesia - two cases. Eur J Neurol 2002;9: 101-4.
6. Kumar N, Ahlskog JE, Klein CJ, et al. Imaging features of cupper deficiency myelopathy: a study of 25 cases. Neuroradiology 2006;48: 78-83.
7. Ahn SC, Brown AW. Cobalamin deficiency and subacute combined degeneration after nitrous oxide anesthesia: a case report. Arch Phys Med Rehabil 2005;86: 150-3.
8. Wackawik A, Luzzio C, Juhasz-Poscine K, et al. Myelo-neuropathy from nitrous oxide abuse: unsually high methylmalonic acid and homocysteine level. Wis Med J 2003;102: 43-5.
9. Gillman MA. Nitrous oxide abuse in perspective. Clin Neuropharmacol 1992;15: 297-306.
10. Ng J, O'Grady G, Pettit T, et al. Nitrous oxide use in first-year students at Auckland University. Lancet 2003;361: 1349-50.
11. Cartner M, Sinnott M, Silburn P. Paralysis caused by "nagging". Med J Aust 2007;187: 366-7.
12. Alt RS, Morrissey RP, Gang MA, et al. Severe myeloneuropathy from acute high-dose nitrous oxide (N2O) abuse. J Emerg Med 2011;41: 378-80.
13. Miller MA, Martinez V, McCarthy R, et al. Nitrous oxide "whippit" abuse presenting as clinical B12 deficiency and ataxia. Am J Emerg Med 2004;22: 124.
14. Shulman RM, Geraghty TJ, Tadros M. A case of unusual substance abuse causing myeloneuropathy. Spinal Cord 2007;45: 314-17.
15. Ng J, Frith R. Nanging. Lancet 2002;360: 384.
16. Tatum WO, Bui DD, Grant EG, et al. Pseudo-guillain-barre syndrome due to "whippet"-induced myeloneuropathy. J Neuroimaging 2010;20: 400-1.
17. Lin RJ, Chen HF, Chang YC, et al. Subacute combined degeneration caused by nitrous oxide intoxication: case reports. Acta Neurol Taiwan 2011;20: 129-37.
18. Vasconcelos OM, Poehm EH, McCarter RJ, et al. Potential outcome factors in subacute combined degeneration: review of observational studies. J Gen Intern Med 2006;21: 1063-8.