Folic acid conjugated guar gum nanoparticles for targeting methotrexate to colon cancer

Journal of Biomedical Nanotechnology

Volumn 9, Issue 1, 2013, Pages 96-106

  Sharma, Monika ^a   Malik, Ritu ^a   Verma, Ashwni ^a   Dwivedi, Pankaj ^a   Banoth, Gabbar Singh ^a   Pandey, Nagendra ^a   Sarkar, Jayant ^a   Mishra, Prabhat Ranjan ^a   Dwivedi, Anil Kumar ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Folic Acid; Guar Gum; Methotrexate; Nanoparticles; Targeted Delivery

Indexed keywords

FOLIC ACIDS; GUAR GUMS; METHOTREXATE; MONO-DISPERSE PARTICLES; POLYDISPERSITY INDICES; SIZE AND SIZE DISTRIBUTIONS; SURFACE MODIFIED NANOPARTICLES; TARGETED DELIVERY;

DIFFERENTIAL SCANNING CALORIMETRY; DISEASES; DRUG THERAPY; EMULSIFICATION; ORGANIC ACIDS; POLYDISPERSITY; ZETA POTENTIAL;

NANOPARTICLES;

ANTINEOPLASTIC AGENT; FOLATE RECEPTOR; GUAR GUM; METHOTREXATE; METHOTREXATE FOLIC ACID GUAR GUM NANOPARTICLE; NANOPARTICLE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CHEMICAL MODIFICATION; COLORECTAL CARCINOMA; COMPETITIVE INHIBITION; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CROSS LINKING; DIFFERENTIAL SCANNING CALORIMETRY; DRUG CONJUGATION; DRUG FORMULATION; DRUG UPTAKE; EMULSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; INFRARED SPECTROSCOPY; INTESTINE FLUID; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PROTEIN LOCALIZATION; RAT; SCANNING ELECTRON MICROSCOPY; ZETA POTENTIAL;

ANIMALS; CACO-2 CELLS; CALORIMETRY, DIFFERENTIAL SCANNING; CELL SURVIVAL; COLONIC NEOPLASMS; CROSS-LINKING REAGENTS; DRUG DELIVERY SYSTEMS; FOLIC ACID; GALACTANS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MANNANS; METHOTREXATE; NANOPARTICLES; PARTICLE SIZE; PLANT GUMS; RATS; RATS, WISTAR; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STATIC ELECTRICITY;

EID: 84876520568     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2013.1474     Document Type: Article

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