메뉴 건너뛰기




Volumn 5, Issue 6, 2013, Pages 1854-1858

Paclitaxel disrupts polarized entry of membrane-permeable C6 ceramide into ovarian cancer cells resulting in synchronous induction of cell death

Author keywords

AKT; C6 ceramide; Ovarian cancer; Paclitaxel

Indexed keywords

AQUAPORIN; C6 CERAMIDE; CERAMIDE; DOXORUBICIN; PACLITAXEL; UNCLASSIFIED DRUG;

EID: 84876494388     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2013.1305     Document Type: Article
Times cited : (8)

References (25)
  • 1
    • 0032553310 scopus 로고    scopus 로고
    • Tumor necrosis factor induces ceramide oscillations and negatively controls sphingolipid synthases by caspases in apoptotic Kym-1 cells
    • Bourteele S, Hausser A, Döppler H, Horn-Müller J, Röpke C, Schwarzmann G, Pfzenmaier K and Müller G: Tumor necrosis factor induces ceramide oscillations and negatively controls sphingolipid synthases by caspases in apoptotic Kym-1 cells. J Biol Chem 273: 31245-31251, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 31245-31251
    • Bourteele, S.1    Hausser, A.2    Döppler, H.3    Horn-Müller, J.4    Röpke, C.5    Schwarzmann, G.6    Pfzenmaier, K.7    Müller, G.8
  • 2
    • 0033615660 scopus 로고    scopus 로고
    • Binding of the human papillomavirus type 16 p97 promoter by the adeno-associated virus Rep78 major regulatory protein correlates with inhibition
    • Zhan D, Santin AD, Liu Y, Parham GP, Li C, Meyers C and Hermonat PL: Binding of the human papillomavirus type 16 p97 promoter by the adeno-associated virus Rep78 major regulatory protein correlates with inhibition. J Biol Chem 274: 31619-31624, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 31619-31624
    • Zhan, D.1    Santin, A.D.2    Liu, Y.3    Parham, G.P.4    Li, C.5    Meyers, C.6    Hermonat, P.L.7
  • 4
    • 0031019309 scopus 로고    scopus 로고
    • Agents that reverse multidrug resistance, tamoxifen, verapamil and cyclosporin A, block glyco-sphingolipid metabolism by inhibiting ceramide glycosylation in human cancer cells
    • Lavie Y, Cao HT, Volner A, Lucci A, Han TY, Geffen V, Giuliano AE and Cabot MC: Agents that reverse multidrug resistance, tamoxifen, verapamil and cyclosporin A, block glyco-sphingolipid metabolism by inhibiting ceramide glycosylation in human cancer cells. J Biol Chem 272: 1682-1687, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 1682-1687
    • Lavie, Y.1    Cao, H.T.2    Volner, A.3    Lucci, A.4    Han, T.Y.5    Geffen, V.6    Giuliano, A.E.7    Cabot, M.C.8
  • 8
    • 0033194699 scopus 로고    scopus 로고
    • Modification of ceramide metabolism increases cancer cell sensitivity to cytotoxics
    • Lucci A, Han TY, Liu YY, Giuliano AE and Cabot MC: Modification of ceramide metabolism increases cancer cell sensitivity to cytotoxics. Int J Oncol 15: 541-546, 1999.
    • (1999) Int J Oncol , vol.15 , pp. 541-546
    • Lucci, A.1    Han, T.Y.2    Liu, Y.Y.3    Giuliano, A.E.4    Cabot, M.C.5
  • 9
    • 0020532762 scopus 로고
    • Taxol effect on tubulin polymerization and associated guanosine 5'-triphosphate hydrolysis
    • Carlier MF and Pantaloni D: Taxol effect on tubulin polymerization and associated guanosine 5'-triphosphate hydrolysis. Biochemistry 22: 4814-4822, 1983.
    • (1983) Biochemistry , vol.22 , pp. 4814-4822
    • Carlier, M.F.1    Pantaloni, D.2
  • 13
    • 79954451114 scopus 로고    scopus 로고
    • Effect of radiation on nasal mucosa and the microvascular casting of guinea pig
    • In Chinese
    • Liu Y, Qiu L and Li C: Effect of radiation on nasal mucosa and the microvascular casting of guinea pig. Lin Chuang Er Bi Yan Hou Ke Za Zhi 20: 793-796, 2006 (In Chinese).
    • (2006) Lin Chuang Er Bi Yan Hou Ke Za Zhi , vol.20 , pp. 793-796
    • Liu, Y.1    Qiu, L.2    Li, C.3
  • 14
    • 34548686539 scopus 로고    scopus 로고
    • Paclitaxel and ceramide co-administration in biodegradable polymeric nanoparticulate delivery system to overcome drug resistance in ovarian cancer
    • Devalapally H, Duan Z, Seiden MV and Amiji MM: Paclitaxel and ceramide co-administration in biodegradable polymeric nanoparticulate delivery system to overcome drug resistance in ovarian cancer. Int J Cancer 121: 1830-1838, 2007.
    • (2007) Int J Cancer , vol.121 , pp. 1830-1838
    • Devalapally, H.1    Duan, Z.2    Seiden, M.V.3    Amiji, M.M.4
  • 15
    • 34249819060 scopus 로고    scopus 로고
    • A CERTain role for ceramide in taxane-induced cell death
    • Kolesnick R, Altieri D and Fuks Z: A CERTain role for ceramide in taxane-induced cell death. Cancer Cell 11: 473-475, 2007.
    • (2007) Cancer Cell , vol.11 , pp. 473-475
    • Kolesnick, R.1    Altieri, D.2    Fuks, Z.3
  • 18
    • 34547619923 scopus 로고    scopus 로고
    • Paclitaxel and ceramide synergis-tically induce cell death with transient activation of EGFR and ERK pathway in pancreatic cancer cells
    • Qiu L, Zhou C, Sun Y, Di W, Scheffer E, Healey S, Wanebo H, Kouttab N, Chu W and Wan Y: Paclitaxel and ceramide synergis-tically induce cell death with transient activation of EGFR and ERK pathway in pancreatic cancer cells. Oncol Rep 16: 907-913, 2006.
    • (2006) Oncol Rep , vol.16 , pp. 907-913
    • Qiu, L.1    Zhou, C.2    Sun, Y.3    Di, W.4    Scheffer, E.5    Healey, S.6    Wanebo, H.7    Kouttab, N.8    Chu, W.9    Wan, Y.10
  • 19
    • 77952927745 scopus 로고    scopus 로고
    • Vascular barrier regulation by PAF, ceramide, caveolae and NO - an intricate signaling network with discrepant effects in the pulmonary and systemic vasculature
    • Kuebler WM, Yang Y, Samapati R and Uhlig S: Vascular barrier regulation by PAF, ceramide, caveolae and NO - an intricate signaling network with discrepant effects in the pulmonary and systemic vasculature. Cell Physiol Biochem 26: 29-40, 2010.
    • (2010) Cell Physiol Biochem , vol.26 , pp. 29-40
    • Kuebler, W.M.1    Yang, Y.2    Samapati, R.3    Uhlig, S.4
  • 21
    • 78650237126 scopus 로고    scopus 로고
    • Pancreatic beta-cells: Role of glycerol and aquaglyceroporin 7
    • Virreira M, Perret J and Delporte C: Pancreatic beta-cells: Role of glycerol and aquaglyceroporin 7. Int J Biochem Cell Biol 43: 10-13, 2011.
    • (2011) Int J Biochem Cell Biol , vol.43 , pp. 10-13
    • Virreira, M.1    Perret, J.2    Delporte, C.3
  • 22
    • 0347624704 scopus 로고    scopus 로고
    • Aquaporin 3 colocates with phospholipase d2 in caveolin-rich membrane microdomains and is downregulated upon keratinocyte differentiation
    • Zheng X and Bollinger Bollag W: Aquaporin 3 colocates with phospholipase d2 in caveolin-rich membrane microdomains and is downregulated upon keratinocyte differentiation. J Invest Dermatol 121: 1487-1495, 2003.
    • (2003) J Invest Dermatol , vol.121 , pp. 1487-1495
    • Zheng, X.1    Bollinger Bollag, W.2
  • 23
    • 33845188255 scopus 로고    scopus 로고
    • EGFR-mediated expression of aquaporin-3 is involved in human skin fbroblast migration
    • Cao C, Sun Y, Healey S, Bi Z, Hu G, Wan S, Kouttab N, Chu W and Wan Y: EGFR-mediated expression of aquaporin-3 is involved in human skin fbroblast migration. Biochem J 400: 225-234, 2006.
    • (2006) Biochem J , vol.400 , pp. 225-234
    • Cao, C.1    Sun, Y.2    Healey, S.3    Bi, Z.4    Hu, G.5    Wan, S.6    Kouttab, N.7    Chu, W.8    Wan, Y.9
  • 25
    • 18844392024 scopus 로고    scopus 로고
    • Emerging drugs for ovarian cancer
    • Kelland LR: Emerging drugs for ovarian cancer. Expert Opin Emerg Drugs 10: 413-424, 2005.
    • (2005) Expert Opin Emerg Drugs , vol.10 , pp. 413-424
    • Kelland, L.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.