Enhanced 15-lipoxygenase activity and elevated eicosanoid production in kidney tumor microenvironment contribute to the inflammation and immune suppression

OncoImmunology

Volumn 1, Issue 2, 2012, Pages 249-251

  Kusmartsev, Sergei ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

15 lipoxygenase; Cancer inflammation; CCL2; Eicosanoids; IL 10; Immune supporession; Kidney cancer; T regs; Tumor associated macrophages

Indexed keywords

15 HYDROXYICOSATETRAENOIC ACID; 15 LIPOXYGENASE 1; 15 LIPOXYGENASE 2; ARACHIDONATE 15 LIPOXYGENASE; ARACHIDONIC ACID; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INTERLEUKIN 10; MACROPHAGE DERIVED CHEMOKINE; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

15ALOX GENE; 15ALOXB GENE; CANCER GROWTH; CANCER IMMUNOTHERAPY; CANCER SURVIVAL; ENZYME ACTIVITY; ENZYME INHIBITION; FATTY ACID SYNTHESIS; GENE; HUMAN; IMMUNE DEFICIENCY; INFLAMMATION; KIDNEY CARCINOMA; LYMPHOCYTIC INFILTRATION; MACROPHAGE MIGRATION; MOLECULAR INTERACTION; NOTE; OVERALL SURVIVAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; REGULATORY T LYMPHOCYTE; TUMOR ASSOCIATED LEUKOCYTE; TUMOR MICROENVIRONMENT;

EID: 84876486244     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.4161/onci.1.2.18502     Document Type: Note

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