Autologous hematopoietic stem cell transplantation following pulsed cyclophosphamide in a severely disabled patient with malignant multiple sclerosis

Journal of Neurology

Volumn 260, Issue 3, 2013, Pages 914-916

  Alix, James J P ^a,b   Blackburn, Daniel J ^a,b   Sokhi, Dilraj ^b   Craven, Ian ^b   Sharrack, Basil ^a,b   Snowden, John A ^b  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b ROYAL HALLAMSHIRE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALEMTUZUMAB; CARMUSTINE; CYCLOPHOSPHAMIDE; GRANULOCYTE COLONY STIMULATING FACTOR; METHYLPREDNISOLONE; OLIGOCLONAL BAND; THYMOCYTE ANTIBODY;

ADULT; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; CASE REPORT; CEREBROSPINAL FLUID ANALYSIS; DEMYELINATING DISEASE; DISABILITY SEVERITY; DISABLED PERSON; DRUG PULSE THERAPY; ENCEPHALOMYELITIS; FEMALE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; LETTER; MULTIPLE SCLEROSIS; NEUROIMAGING; PLASMAPHERESIS; PRIORITY JOURNAL; QUADRIPLEGIA; SENSORIMOTOR FUNCTION; VERTIGO; VISUAL ACUITY;

CYCLOPHOSPHAMIDE; DISABLED PERSONS; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; MULTIPLE SCLEROSIS; PULSE THERAPY, DRUG; TRANSPLANTATION, AUTOLOGOUS; YOUNG ADULT;

EID: 84876479850     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-012-6796-8     Document Type: Letter

References (10)

1. Capello E, Mancardi GL (2004) Marburg type and Balò's concentric sclerosis: rare and acute variants of multiple sclerosis. Neurol Sci 25(Suppl 4):S361-S363
2. Reston JT, Uhl S, Treadwell JR, Nash RA, Schoelles K (2011) Autologous hematopoietic cell transplantation for multiple sclerosis: a systematic review. Mult Scler 17:204-213
3. Fagius J, Lundgren J, Oberg G (2009) Early highly aggressive MS successfully treated by hematopoietic stem cell transplantation. Mult Scler 15:229-237
4. Snowden JA, Saccardi R, Allez M, Ardizzone S, Arnold R, Cervera R, Denton C, Hawkey C, Labopin M, Mancardi G, Martin R, Moore JJ, Passweg J, Peters C, Rabusin M, Rovira M, van Laar JM, Farge D (2012) Haematopoietic SCT in severe autoimmune diseases: updated guidelines of the European Group for Blood and Marrow Transplantation. Bone Marrow Transplant 47:770-790
5. Mancardi GL, Murialdo A, Rossi P, Gualandi F, Martino G, Marmont A, Ciceri F, Schenone A, Parodi RC, Capello E, Comi G, Uccelli A (2005) Autologous stem cell transplantation as rescue therapy in malignant forms of multiple sclerosis. Mult Scler 11:367-371
6. Burt RK, Balabanov R, Voltarelli J, Barreira A, Burman J (2012) Autologous hematopoietic stem cell transplantation for multiple sclerosis-if confused or hesitant, remember: 'treat with standard immune suppressive drugs and if no inflammation, no response'. Mult Scler 18:772-775
7. Burt RK, Loh Y, Cohen B, Stefoski D, Stefosky D, Balabanov R, Katsamakis G, Oyama Y, Russell EJ, Stern J, Muraro P, Rose J, Testori A, Bucha J, Jovanovic B, Milanetti F, Storek J, Voltarelli JC, Burns WH (2009) Autologous non-myeloablative haemopoietic stem cell transplantation in relapsing-remitting multiple sclerosis: a phase I/II study. Lancet Neurol 8:244-253
8. Le Bouc R, Zéphir H, Majed B, Vérier A, Marcel M, Vermersch P (2012) No increase in cancer incidence detected after cyclophosphamide in a French cohort of patients with progressive multiple sclerosis. Mult Scler 18:55-63
9. Gauthier SA, Weiner HL (2005) Cyclophosphamide therapy for MS. Int MS J 12:52-58
10. Saccardi R, Freedman MS, Sormani MP, Atkins H, Farge D, Griffith LM, Kraft G, Mancardi GL, Nash R, Pasquini M, Martin R, Muraro PA, Group EBaMT, Research CfIBaM, Group HiMIS (2012) A prospective, randomized, controlled trial of autologous haematopoietic stem cell transplantation for aggressive multiple sclerosis: a position paper. Mult Scler 18:825-834