Deficiency of a New Protein Associated with Cardiac Syndrome X; Called Adropin

Cardiovascular Therapeutics

Volumn 31, Issue 3, 2013, Pages 174-178

  Celik, Ahmet ^a   Balin, Mehmet ^a   Kobat, Mehmet Ali ^a   Erdem, Kenan ^a   Baydas, Adil ^a   Bulut, Musa ^b   Altas, Yakup ^a   Aydin, Suna ^a   Aydin, Suleyman ^c  

^a Elazig Education and Research Hospital ^*  (Turkey)

^b MALATYA STATE HOSPITAL   (Turkey)

^c FIRAT UNIVERSITY   (Turkey)

Author keywords

Adropin; Cardiac syndrome X; Endothelial dysfunction

Indexed keywords

ADROPIN; NITRATE; NITRITE; PROTEIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BODY MASS; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEFICIENCY; SENSITIVITY AND SPECIFICITY; SYNDROME X;

ADULT; AGED; BLOOD PROTEINS; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; MALE; MICROVASCULAR ANGINA; MIDDLE AGED; ROC CURVE;

EID: 84876471358     PISSN: 17555914     EISSN: 17555922     Source Type: Journal    
DOI: 10.1111/1755-5922.12025     Document Type: Article

References (28)

1. Vermeltfoort IA, Raijmakers PG, Riphagen II, Odekerken DA, Kuijper AF, Zwijnenburg A, Teule GJ. Definitions and incidence of cardiac syndrome X: review and analysis of clinical data. Clin Res Cardiol 2010;99:475-481.
2. Motz W, Vogt M, Rabenau O, Scheler S, Lückhoff A, Strauer BE. Evidence of endothelial dysfunction in coronary resistance vessels in patients with angina pectoris and normal coronary angiograms. Am J Cardiol 1991;68:996-1003.
3. Epstein SE, Cannon RO III. Site of increased resistance to coronary flow in patients with angina pectoris and normal epicardial coronary arteries. J Am Coll Cardiol 1986;8:459-461.
4. Vázquez-Rey E, Kaski JC. Cardiovascular syndrome X and endothelial dysfunction. Rev Esp Cardiol 2003;56:181-192.
5. Cooke JP, Rossitch E Jr, Andon NA, Loscalzo J, Dzau VJ. Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator. J Clin Invest 1991;88:1663-1671.
6. Kumar KG, Trevaskis JL, Lam DD, et al. Identification of adropin as a secreted factor linking dietary macronutrient intake with energy homeostasis and lipid metabolism. Cell Metab 2008;8:468-481.
7. Lovren F, Pan Y, Quan A, et al. Adropin is a novel regulator of endothelial function. Circulation 2010;122(11 Suppl):S185-S192.
8. Lanza GA. Cardiac syndrome X: a critical overview and future perspectives. Heart 2007;93:159-166.
9. Bruce RA, Blackmon JR, Jones JW, Strait G. Exercising testing in adult normal subjects and cardiac patients. Pediatrics. 1963;32(Suppl):742-756.
10. Mark DB, Hlatky MA, Harrell FE Jr, Lee KL, Califf RM, Pryor DB. Exercise treadmill score for predicting prognosis in coronary artery disease. Ann Intern Med, 1987;106:793-800.
11. Cerqueira MD, Weissman NJ, Dilsizian V, et al. American Heart Association Writing Group on Myocardial Segmentation and Registration for Cardiac Imaging. Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart: a statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association. Circulation 2002;105:539-542.
12. Aydin S. A comparison of ghrelin, glucose, alpha-amylase and protein levels in saliva from diabetics. J Biochem Mol Biol 2007;40:29-35.
13. Bonora E, Targher G, Alberiche M, et al. Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity. Diabetes Care 2000;23:57-63.
14. Aydin S, Aydin S, Croteau AG, Sahin I, Citil C. Ghrelin, nitrite and paraoxonase/arylesterase concentrations in cement plant workers. J Med Biochem 2010;29:78-83.
15. Bories PN, Bories C. Nitrate determination in biological fluids by an enzymatic one-step assay with nitrate reductase. Clin Chem 1995;41:904-907.
16. Gutman SI, Hollywood CA. Simple, rapid method for determining nitrates and nitrites in biological fluids. Clin Chem 1992;38:2152.
17. Nithipatikom K, Pratt PF, Campbell WB. Nitro-Larginine interferes with the cadmium reduction of nitrate/griess reaction method of measuring nitric oxide production. Eur J Clin Chem Clin Biochem 1996;34:133-137.
18. Kubes P, Suzuki M, Granger DN. Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci USA 1991;88:4651-4655.
19. Wolf A, Zalpour C, Theilmeier G, et al. Dietary L-arginine supplementation normalizes platelet aggregation in hypercholesterolemic humans. J Am Coll Cardiol 1997;29:479-485.
20. Hogg N, Kalyanaraman B, Joseph J, Struck A, Parthasarathy S. Inhibition of low-density lipoprotein oxidation by nitric oxide. Potential role in atherogenesis. FEBS Lett 1993;334:170-174.
21. Boger RH, Bode-Boger SM, Kienke S, Stan AC, Nafe R, Frölich JC. Dietary L-arginine decreases myointimal cell proliferation and vascular monocyte accumulation in cholesterol-fed rabbits. Atherosclerosis 1998;136:67-77.
22. Lian W, Gu X, Qin Y, Zheng X. Elevated plasma levels of adropin in heart failure patients. Intern Med 2011;50:1523-1527.
23. Ganesh Kumar K, Zhang J, Gao S, et al. Adropin deficiency is associated with increased adiposity and insulin resistance. Obesity (Silver Spring) 2012;20:1394-1402. Doi: 10. 1038/oby.2012. 31.
24. Kaski JC, Rosano GM, Collins P, Nihoyannopoulos P, Maseri A, Poole-Wilson PA. Cardiac syndrome X: clinical characteristics and left ventricular function. Long-term follow-up study. J Am Coll Cardiol 1995;25:807-814.
25. Bugiardini R, Bairey Merz CN. Angina with 'normal' coronary arteries: a changing philosophy. JAMA 2005;293:477-484.
26. Atienza F, Velasco JA, Brown S, Ridocci F, Kaski JC. Assessment of quality of life in patients with chest pain and normal coronary arteriogram (syndrome X) using a specific questionnaire. Clin Cardiol 1999;22:283-290.
27. Fox K, Garcia MA, Ardissino D, et al. ; Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology; ESC Committee for Practice Guidelines (CPG). Guidelines on the management of stable angina pectoris: executive summary: the task force on the management of stable angina pectoris of the European society of cardiology. Eur Heart J 2006;27:1341-1381.
28. Vestergaard H, Skøtt P, Steffensen R, Wroblewski H, Pedersen O, Kastrup J. Insulin-resistant glucose metabolism in patients with microvascular angina-syndrome X. Metabolism 1995;44:876-882.