Dilemmas about the toxicological consequences of metal-on-metal hip prostheses-What we do and do not know, and what we should do?

Clinical Toxicology

Volumn 51, Issue 4, 2013, Pages 195-198

  Brent, Jeffrey ^a   Devlin, John J ^b  

^a UNIVERSITY OF COLORADO   (United States)

^b EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMIUM; COBALT; METAL;

ACETABULUM; CARDIOMYOPATHY; DEMYELINATING NEUROPATHY; GOITER; HASHIMOTO DISEASE; HEARING IMPAIRMENT; HIP PROSTHESIS; HUMAN; HYPOTHYROIDISM; METAL ON METAL JOINT PROSTHESIS; NOTE; PERIPHERAL NEUROPATHY; POLYNEUROPATHY; VISUAL IMPAIRMENT;

ANIMALS; ARTHROPLASTY, REPLACEMENT, HIP; CHROMIUM; COBALT; EVIDENCE-BASED MEDICINE; HIP PROSTHESIS; HUMANS; INDIVIDUALIZED MEDICINE; METAL-ON-METAL JOINT PROSTHESES; METALS, HEAVY; POISONING; POSTOPERATIVE COMPLICATIONS;

EID: 84876463283     PISSN: 15563650     EISSN: 15569519     Source Type: Journal    
DOI: 10.3109/15563650.2013.784326     Document Type: Note

References (26)

1. Rizetti MC, Liberini P, Zarattini G, Catalani S, Pazzaglia U, Apostoli P, Padovani A. Loss of sight and sound. Could it be the hip? Lancet 2009; 272:1052.
2. Berk L, Burchenal JH, Castle WB. Erythropoietic effect of cobalt in patients with or without anemia. N Eng J Med 1949; 240:754-762.
3. Gross RT, Kriss JP, Spaet TH. Hematopoietic and goitrogenic effects of cobaltous chloride in patients with sickle cell anemia. Am J Dis Child 1954; 88:284-290.
4. Gross RT, Kriss JP, Spaet TH. The hematopoietic and goitrogenic effects of cobaltous chloride in patients with sickle cell anemia. Peds 1955; 15:284-294.
5. Kriss JP, Carnes WH, Gross RT. Hypothyroidism and thyroid hyper-plasia in patients treated with cobalt. JAMA 1955; 157:117-121.
6. Robey JS, Veazel PM, Crawford JD. Cobalt-induced myxedema. N Eng J Med 1956; 255:955-957.
7. Chamberlain JL. Thyroid enlargement probably induced by cobalt. J Peds 1961; 59:81-86.
8. Washburn TC, Kaplan E. Cobalt therapy and goiter. Clin Peds 1964; 3: 89-92.
9. Bowie EA, Hurley PJ. Cobalt chloride in the treatment of refractory anaemia in patients undergoing long-term haemodialysis. Aust NZ J Med 1975; 5:306-314.
10. Licht A. Optic atrophy following treatment with cobalt chloride in a patient with pancytopenia and hypercellular marrow. Isr J Med Sci 1972; 8: 61-66.
11. Schirrmacher UOE. Case of cobalt poisoning. Br Med J 1967; 1: 544-545.
12. McDermott PH, Delaney RL, Egan JD, Sullivan JF. Myocardosis and cardiac failure in men. JAMA 1966; 198:253-256.
13. Kesteloot H, Roelandt J, Willems J, Claes JH, Joossens JV. An enquiry into the role of cobalt in the heart disease of chronic beer drinkers. J Am Heart Assoc 1968; 37:854-864.
14. Alexander CS. Cobalt-beer cardiomyopathy. A clinical and pathologic study of twenty-eight cases. Am J Med 1972; 53: 395-417.
15. Seghizzi P, D'Adda F, Borleri D, Barbic F, Mosconi G. Cobalt myocardiopathy. A critical review of literature. Sci Total Environ 1994; 180:105-109. (Pubitemid 24210691)
16. Tower SS. Arthroprosthetic cobaltism: Neurological and cardiac manifestations in two patients with metal-on-metal arthroplasty: A case report. J Bone Joint Surg 2010; 92:2847-2851.
17. Pelclova D, Sklensky M, Janicek P, Lach K: Severe cobalt intoxication following hip replacement revision: Clinical ceatures and outcome. Clin Tox 2012; 50:262-265.
18. Steens W, von Foerster G, Katzer A. Severe cobalt poisoning with loss of sight after ceramic-metal pairing in a hip-a case report. Acta Orthopaedica 2006; 77:830-832. (Pubitemid 44521928)
19. Oldenburg M, Wegner R, Baur X. Severe cobalt intoxication due to prosthesis wear in repeated total hip arthroplasty. J Arthroplasty 2009; 24:502.e15-e19.
20. Ikeda T, Takahashi K, Kabata T, Sakagoshi D, Tomita K, Yamada M. Polyneuropathy caused by cobalt-chromium metalossis after total hip replacement. Muscle Nerve 2010; 42:140-143.
21. Anon. Chromium (VI) compounds. IARC monographs on the evaluation of carcinogenic risks to humans. 2012; 100:147-167.
22. Howie DW, Rogers SD, McGee MA, Haynes DDR. Biological effects of cobalt chrome in cell and animal models. Clin Ortho Relat Res 1996; 329s:s217-s232.
23. Newton AW, Ranganath L, Armstrong C, Peter V, Roberts NB. Differential distribution of cobalt, chromium, and nickel between whole blood, plasma and urine in patients after metal-on-metal (MoM) hip arthroplasty. J Orthop Res 2012; 30:1640-1646.
24. Walter LR, Marel E, Harbury R, Wearne J. Distribution of chromium and cobalt ions in various blood fractions after resurfacing hip arthro-plasty. Arthroplasty 2008; 23:814-822.
25. Kwon YM, Thomas P, Summer B, Pandit H, Taylor A, Beard D, et al. Lymphocyte proliferation responses in patients with pseudotumors following metal-on-metal hip resurfacing arthroplasty. J Orthop Res 2010; 28:444-450.
26. Medicines and Healthcare products Regulatory Agency 2012. Medical Device Alert re: All meta-on-metal (MoM) hip replacements. MDA/2012/036, Pgs. 1-7. http://www.mhra.gov.uk/Publications/Safetywarnings/MedicalDeviceAlerts/ CON155761 (Accessed March 3, 2012).