Antihyperglycemic activity of extracts from Boldoa purpurascens leaves in alloxan-induced diabetic rats

Phytotherapy Research

Volumn 27, Issue 5, 2013, Pages 721-724

  Gonzalez Mosquera D M ^a   Hernandez Ortega, Y ^a   By, B ^a   Vicet Muro, L ^a   Saucedo Hernandez, Y ^a   Grau Abalos R ^a   Dehaen, W ^b   Pieters, L ^c   Apers, S ^c  

^a CENTRAL UNIVERSITY OF LAS VILLAS   (Cuba)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Boldoa purpurascens; D pinitol; flavonoids; hypoglycemic activity; Nyctaginaceae

Indexed keywords

ALCOHOL; ANTIDIABETIC AGENT; BOLDOA PURPURASCENS EXTRACT; FLAVONOID; GLUCOSE; INSULIN; METFORMIN; PINITOL; PLANT EXTRACT; SODIUM CHLORIDE; UNCLASSIFIED DRUG; WATER;

ALLOXAN DIABETES MELLITUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDIABETIC ACTIVITY; ARTICLE; BOLDOA PURPURASCENS; DIABETES MELLITUS; FEMALE; GLUCOSE BLOOD LEVEL; MALE; MEDICINAL PLANT; NONHUMAN; PHYTOCHEMISTRY; PLANT LEAF;

ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; HYPOGLYCEMIC AGENTS; INOSITOL; MALE; METFORMIN; NYCTAGINACEAE; PLANT EXTRACTS; PLANT LEAVES; RATS; RATS, WISTAR;

NYCTAGINACEAE; RATTUS;

EID: 84876462820     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.4769     Document Type: Article

References (15)

1. Bates SH, Jones RB, Bailey C.J,. 2000. Insulin-like effect of pinitol. Br J Pharmacol 130: 1944-1948.
2. Bebrevska L, Foubert K, Hermans N, et al,. 2010. In vivo antioxidative activity of a quantified Pueraria lobata root extract. J Ethnopharmacol 127: 112-117.
3. 13C NMR spectrum of 1,4-O, O-dimethyl-chiro-inositol. Austr. J. Chem. 29: 1115-1118.
4. Davis A, Christiansen M, Horowitz JF, Klein S, Hellerstein MK, Ostlund RE,. 2000. Effect of pinitol treatment on insulin action in subjects with insulin resistance. Diabetes Care 23: 1000-1005.
5. Edem DO, 2009. Hypoglycemic Effects of Ethanolic Extracts of Alligator Pear Seed (Persea Americana Mill) in Rats. Eur. J. Scient. Res. 33: 669-678.
6. Gonzalez Mosquera DM, Kilonda A, Toppet S, et al,. 2008. New flavonoids from Boldoa purpurascens Cav. Planta Med 74: 1468-1473.
7. Gonzalez Mosquera DM, Hernandez OY, Kilonda A, Dehaen W, Pieters L, Apers S,. 2011. Evaluation of the in vivo anti-inflammatory activity of a flavonoid glycoside from Boldoa purpurascens. Phytochem. Lett. 4: 231-234.
8. Grover JK, Vats V, Rathi SS,. 2000. Antihyperglycemic effect of Eugenia jambolana and Tinospora cordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism. J Ethnopharmacol, 73: 461-470.
9. Larner J,. 2002. D-chiro-Inositol-Its functional role in insulin action and its deficit in insulin resistance. Int J Exp Diabetes Res 3: 47-60.
10. Lenzen S,. 2008. The mechanisms of alloxan and streptozotocin induced diabetes. Acta Diabetol 51: 216-226.
11. Miranda M, Cuellar A,. 2000. Laboratory Practice Manual of Pharmacognosy and Natural Products. Cuba: Havana University.
12. Morelli V, Zoorob RJ,. 2000. Alternative Therapies: Part I. Depression, Diabetes, and Obesity. Ann. Fam. Physician, 62: 1051-60.
13. Prince SM, Menon VP, 2000. Hypoglycemic and other related actions of Tinospora cardifolia roots in alloxan induced diabetic rats. J Ethnopharmacol 70: 9-15.
14. Roig Mesa JT, 1988. Medicinal, aromatic and poisonous plants of Cuba. Fourth Edition.
15. Sharma VJ, Shah UD,. 2010. Antihyperglycemic activity of flavonoids from methanolic extract of aerial parts of Scoparia dulcis in streptozotocon induced diabetic rats. Int. J. Chem. Tech. Research 2: 214-218.