Prevalence and key covariates of non-medical prescription opioid use among the general secondary student and adult populations in Ontario, Canada

Drug and Alcohol Review

Volumn 32, Issue 3, 2013, Pages 276-287

  Fischer, Benedikt ^a,b   Ialomiteanu, Anca ^b   Boak, Angela ^b   Adlaf, Edward ^b,c   Rehm, Jürgen ^b,c,d   Mann, Robert E ^b,c  

^a SIMON FRASER UNIVERSITY   (Canada)

^b CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Adults; Canada; Non medical use; Prescription opioids; Students

Indexed keywords

NARCOTIC ANALGESIC AGENT;

ADOLESCENT; ADULT; AGE; ARTICLE; CANADA; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; FEMALE; HEALTH SURVEY; HUMAN; MALE; METHODOLOGY; MIDDLE AGED; OPIATE ADDICTION; PREVALENCE; PSYCHOLOGICAL ASPECT; RANDOMIZED CONTROLLED TRIAL; STUDENT; YOUNG ADULT;

ADOLESCENT; ADULT; AGE FACTORS; ANALGESICS, OPIOID; CANADA; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; ONTARIO; OPIOID-RELATED DISORDERS; POPULATION SURVEILLANCE; PREVALENCE; STUDENTS; YOUNG ADULT;

EID: 84876425170     PISSN: 09595236     EISSN: 14653362     Source Type: Journal    
DOI: 10.1111/dar.12025     Document Type: Article

References (74)

1. United Nations Office on Drugs and Crime (UNODC). World Drug Report 2011. Vienna: United Nations Office on Drugs and Crime, 2011. Available at: http://www.unodc.org/unodc/en/data-and-analysis/WDR-2011.html (accessed May 2012).
2. Manchikanti L, Fellows B, Ailinani H, Pampati V. Therapeutic use, abuse, and nonmedical use of opioids: a ten-year perspective. Pain Physician 2010;13:401-435.
3. Fischer B, Argento E. Prescription opioid related misuse, harms, diversion and interventions in Canada: a review. Pain Physician 2012;15:ES191-ES203.
4. Substance Abuse and Mental Health Services Administration (SAMHSA). National Survey on Drug Use and Health, 2009 and 2010. Rockville: Substance Abuse and Mental Health Services Administration (SAMHSA), Center for Behavioral Health Statistics and Quality, 2011. Available at: http://www.samhsa.gov/data/nsduh/2k10NSDUH/tabs/Sect1peTabs1to46.htm (accessed May 2012).
5. Substance Abuse and Mental Health Services Administration (SAMHSA). Results from the 2010 National Survey on Drug Use and Health: Summary of National Findings. NSDUH Series H-41, HHS Publication No. (SMA) 11-4658. Rockville: Substance Abuse and Mental Health Services Administration (SAMHSA), 2011. Available at: http://www.samhsa.gov/data/NSDUH/2k10NSDUH/2k10Results.htm (accessed May 2012).
6. Johnston LD, O'Malley PM, Bachman JG, Schulenberg JE. Monitoring the future national results on adolescent drug use: overview of key findings, 2011. Ann Arbor: Institute for Social Research, The University of Michigan, 2012.
7. Cai R, Crane E, Poneleit K, Paulozzi L. Emergency department visits involving nonmedical use of selected prescription drugs in the United States, 2004-2008. J Pain Palliat Care Pharmacother 2010;24:293-297.
8. Substance Abuse and Mental Health Services Administration. Drug Abuse Warning Network, 2009: National Estimates of Drug-Related Emergency Department Visits. HHS Publication No. (SMA) 11-4659, DAWN Series D-35. Rockville, MD: Substance Abuse and Mental Health Services Administration, 2011. Available at: http://www.samhsa.gov/data/2k11/dawn/2k9dawned/html/dawn2k9ed.htm (accessed May 2012).
9. Centers for Disease Control and Prevention (CDC). Vital signs: overdoses of prescription opioid pain relievers-United States, 1999-2008. MMWR Morb Mortal Wkly Rep 2011;60:1487-1492.
10. Fischer B, Nakamura N, Urbanoski K, Rush B, Rehm J. Correlations between population levels of prescription opioid use and prescription opioid-related substance use treatment admissions in the US and Canada since 2001. Public Health 2012;126:749-751.
11. Novak S, Nemeth WC, Lawson KA. Trends in medical use and abuse of sustained-release opioid analgesics: a revisit. Pain Med 2004;5:59-65.
12. Wisniewski AM, Purdy CH, Blondell RD. The epidemiologic association between opioid prescribing, non-medical use, and emergency department visits. J Addict Dis 2008;27:1-11.
13. Fischer B, Jones W, Krahn M, Rehm J. Differences and over-time changes in levels of prescription opioid analgesic dispensing from retail pharmacies in Canada, 2005-2010. Pharmacoepidemiol Drug Saf 2011;20:1269-1277.
14. International Narcotics Control Board. Narcotic Drugs: Estimated World Requirements for 2012-Statistics for 2010. New York: United Nations, 2011. Available at: http://www.incb.org/incb/en/narcotic-drugs/Technical_Reports/2011/narcotic-drugs-technical-report_2011.html (accessed May 2012).
15. Fischer B, Rehm J, Goldman B, Popova S. Non-medical use of prescription opioids and public health in Canada: an urgent call for research and interventions development. Can J Public Health 2008;99:182-184.
16. Health Canada. Canadian Alcohol and Drug Use Monitoring Survey (CADUMS): Summary Of Results for 2011. Ottawa: Health Canada, 2012. Available at: http://www.hc-sc.gc.ca/hc-ps/drugs-drogues/stat/_2011/tables-tableaux-eng.php#t1 (accessed November 2012).
17. Health Canada. Canadian Alcohol and Drug Use Monitoring Survey (CADUMS): Summary Results for 2008. Ottawa: Health Canada, 2009. Available at: www.hc-sc.gc.ca/hc-ps/drugs-drogues/stat/_2008/summary-sommaire-eng.php (accessed May 2012).
18. Fischer B, Nakamura N, Iaolomiteanu A, Boak A, Rehm J. Assessing the prevalence of non-medical prescription opioid use in the general Canadian population: methodological issues and questions. Can J Psychiatry 2010;55:606-609.
19. Dhalla IA, Mamdani MM, Sivilotti ML, Kopp A, Qureshi O, Juurlink DN. Prescribing of opioid analgesics and related mortality before and after the introduction of long-acting oxycodone. CMAJ 2009;181:891-896.
20. Fischer B, Nakamura N, Rush B, Rehm J, Urbanoski K. Changes in and characteristics of admissions to treatment related to problematic prescription opioid use in Ontario, 2004-2009. Drug Alcohol Depend 2010;109:257-260.
21. Paglia-Boak A, Adlaf EM, Mann RE. Drug Use Among Ontario Students 1977-2011: OSDUHS Highlights (CAMH Research Document Series No. 33). Toronto: Centre for Addiction and Mental Health (CAMH), 2011.
22. Ialomiteanu A, Adlaf EM. CAMH Monitor 2011 Technical Guide. Toronto: Centre for Addiction and Mental Health (CAMH), 2012. Available at: http://www.camh.net/research/camh_monitor.html (accessed May 2012).
23. Ialomiteanu A, Adlaf EM. CAMH Monitor 2010 Technical Guide. Toronto: Centre for Addiction and Mental Health (CAMH), 2011. Available at: http://www.camh.net/research/camh_monitor.html (accessed May 2012).
24. Becker WC, Sullivan LE, Tetrault JM, Desai RA, Fiellin DA. Non-medical use, abuse and dependence on prescription opioids among U.S. adults: psychiatric, medical and substance use correlates. Drug Alcohol Depend 2008;94:38-47.
25. Martins S, Keyes K, Storr CL, Zhu H, Chilcoat HD. Pathways between nonmedical opioid use/dependence and psychiatric disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Drug Alcohol Depend 2009;103:16-24.
26. McCabe SE, Cranford JA, Boyd CJ. The relationship between past-year drinking behaviors and nonmedical use of prescription drugs: prevalence of co-occurrence in a national sample. Drug Alcohol Depend 2006;84:281-288.
27. Banta-Green CJ, Merrill JO, Doyle SR, Boudreau DM, Calsyn DA. Opioid use behaviors, mental health and pain-development of a typology of chronic pain patients. Drug Alcohol Depend 2009;104:34-42.
28. Korn EL, Graubard BI. Analysis of health surveys. New York: John Wiley and Sons, 1999.
29. Goldberg DP, Williams PD. A user's guide to the General Health Questionnaire. Windsor, Berks: NFER-Nelson, 1988.
30. Goodman E, Adler NE, Kawachi I, Frazier AL, Huang B, Colditz GA. Adolescents' perceptions of social status: development and evaluation of a new indicator. Pediatrics 2001;108:E31.
31. Heeringa S, West BT, Berglund PA. Applied survey data analysis. Boca Raton: Chapman & Hall/CRC Press, 2010.
32. StataCorp. Stata Statistical Software: Release 11. College Station: StataCorp LP, 2009.
33. Mann RE, Stoduto G, Vingilis E, etal. Alcohol and driving factors in collision risk. Accid Anal Prev 2010;42:1538-1544.
34. Kurdyak P, Gomes T, Yao Z, etal. Use of other opioids during methadone therapy: a population-based study. Addiction 2012;107:776-780.
35. McCabe SE, Cranford J, Morales M, Young A. Simultaneous and concurrent polydrug use of alcohol and prescription drugs: prevalence, correlates and consequences. J Stud Alcohol 2006;67:529-537.
36. Wu LT, Pilowsky DJ, Patkar AA. Non-prescribed use of pain relievers among adolescent in the United States. Drug Alcohol Depend 2008;94:1-11.
37. McCabe SE, West B, Wechsler H. Alcohol-use disorders and nonmedical use of prescription drugs among US college students. J Stud Alcohol Drugs 2007;68:543-547.
38. Bauman A, Phongsavan P. Epidemiology of substance use in adolescence: prevalence, trends and policy implications. Drug Alcohol Depend 1999;55:187-207.
39. Duff C. Drugs and youth cultures: is Australia experiencing the 'normalization' of adolescent drug use? J Youth Stud 2003;6:433-447.
40. Paglia A, Room R. Preventing substance use problems among youth: a literature review and recommendations. J Prim Prev 1999;20:3-50.
41. Kaplan HB, Martin SS, Robbins C. Pathways to adolescent drug use: self-derogation, peer influence, weakening of social controls, and early substance use. J Health Soc Behav 1984;25:270-289.
42. Martins SS, Storr CL, Zhu H, Chilcoat HD. Correlates of extramedical use of OxyContin versus other analgesic opioids among the US general population. Drug Alcohol Depend. 2009;99:58-67.
43. Grella CE, Karno MP, Warda US, Niv N, Moore AA. Gender and comorbidity among individuals with opioid use disorders in the NESARC study. Addict Behav 2009;34:498-504.
44. Sung HE, Richter L, Vaughan R, Johnson PB, Thom B. Nonmedical use of prescription opioids among teenagers in the United States: trends and correlates. J Adolesc Health 2005;37:44-51.
45. McCabe SE, Cranford J, West B. Trends in prescription drug abuse and dependence, co-occurrence with other substance use disorders, and treatment utilization: results from two national surveys. Addict Behav 2008;33:1297-1305.
46. McCabe SE, Boyd CJ, Young A. Medical and nonmedical use of prescription drugs among secondary school students. J Adolesc Health 2007;40:76-83.
47. Quintero G, Peterson J, Young B. An exploratory study of socio-cultural factors contributing to prescription drug misuse among college students. J Drug 2006;36:903-931.
48. McCauley JL, Amstadter AB, Macdonald A, etal. Non-medical use of prescription drugs in a national sample of college women. Addict Behav 2011;36:690-695.
49. Green TC, Grimes Serrano JM, Licari A, Budman SH, Butler SF. Women who abuse prescription opioids: findings from the Addiction Severity Index-Multimedia Version Connect prescription opioid database. Drug Alcohol Depend 2009;103:65-73.
50. Zullig KJ, Divin AL. The association between non-medical prescription drug use, depressive symptoms, and suicidality among college students. Addict Behav 2012;37:890-899.
51. Tetrault J, Desai R, Becker W, Fiellin D, Concato J, Sullivan L. Gender and non-medical use of prescription opioids: results from a national US survey. Addiction 2008;103:258-268.
52. Goodman E, Huang B. Socioeconomic status, depressive symptoms, and adolescent substance use. Arch Pediatr Adolesc Med 2002;156:448-453.
53. Tyas SL, Pederson LL. Psychosocial factors related to adolescent smoking: a critical review of the literature. Tob Control 1998;7:409-420.
54. Brennan AF, Walfish S, AuBuchon P. Alcohol use and abuse in college students. II. Social/environmental correlates, methodological issues, and implications for intervention. Int J Addict 1986;21:475-493.
55. Paulozzi L, Xi Y. Recent changes in drug poisoning mortality in the United States by urban-rural status and by drug type. Pharmacoepidemiol Drug Saf 2008;17:997-1005.
56. Cicero TJ, Inciardi JA, Munoz A. Trends in abuse of Oxycontin and other opioid analgesics in the United States: 2002-2004. J Pain 2005;10:662-672.
57. Fischer B, Rehm J. Deaths related to the use of prescription opioids. CMAJ 2009;181:881-882.
58. Room R. Stigma, social inequality and alcohol and drug use. Drug Alcohol Rev 2005;24:143-155.
59. Galea S, Nandi A, Vlahov D. The social epidemiology of substance use. Epidemiol Rev 2004;26:36-52.
60. Jarvis M, Wardle J. Social patterning of individual health behaviours: the case of cigarette smoking. In: Marmot M, Wilkinson R, eds. Social determinants of health. London: Oxford University Press, 1999:240-255.
61. Wardman D, Khan N, El-Guebaly N. Prescription medication use among an aboriginal population accessing addiction treatment. Can J Psychiatry 2002;47:355-360.
62. Nishnawbe Aski Nation Think Tank. Restoring Our Nation: Action Plan For Community Recovery from Opioid Addiction. Ontario: Nishnawbe Aski Nation, 2011.
63. Kelly L, Dooley J, Cromarty H, etal. Narcotic-exposed neonates in a First Nations population in northwestern Ontario: incidence and implications. Can Fam Physician 2011;57:e441-e447.
64. Katt M, Chase C, Samokhvalov A, Argento E, Rehm J, Fischer B. Feasibility and outcomes of a community-based taper-to-low-dose-maintenance suboxone treatment program for prescription opioid dependence in a remote first nations community in Northern Ontario. Journal of Aboriginal Health 2012;9:52-58.
65. Amari E, Rehm J, Goldner E, Fischer B. Nonmedical prescription opioid use and mental health and pain comorbidities: a narrative review. Can J Psychiatry 2011;56:495-502.
66. Boyd CJ, McCabe SE, Cranford JA, Young A. Adolescents' motivations to abuse prescription medications. Pediatrics 2006;118:2472-2480.
67. McCabe SE, Cranford J, Boyd C, Teter C. Motives, diversion and routes of administration associated with nonmedical use of prescription opioids. Addict Behav 2007;32:562-575.
68. McCabe SE, Boyd CJ, Cranford J, Teter CJ. Motives for nonmedical use of prescription opioids among high school seniors in the United States: self-treatment and beyond. Arch Pediatr Adolesc Med 2009;163:739-744.
69. Zacny JP, Lichtor SA. Nonmedical use of prescription opioids: motives and ubiquity issues. J Pain 2008;9:473-486.
70. Gilson AM, Kreis PG. The burden of the nonmedical use of prescription opioid analgesics. Pain Med 2009;10:S89-S100.
71. Brener ND, Billy JOG, Grady WR. Assessment of factors affecting the validity of self-reported health-risk behavior among adolescents: evidence from the scientific literature. J Adolesc Health 2003;33:436-457.
72. Delaney-Black V, Chiodo LM, Hannigan JH, etal. Just say 'I don't': lack of concordance between teen report and biological measures of drug use. Pediatrics 2010;126:887-893.
73. Tourangeau R, Yan T. Sensitive questions in surveys. Psychol Bull 2007;133:859-883.
74. McCambridge J, Strang J. The reliability of drug use data collected in the classroom: what is the problem, why does it matter and how should it be approached? Drug Alcohol Rev 2006;25:413-418.