Increased expression of ADAM33 protein in asthmatic patients as compared to non-asthmatic controls

Indian Journal of Medical Research

Volumn 137, Issue 3, 2013, Pages 507-514

  Tripathi, Priya ^a   Awasthi, Shally ^a   Husain, Nuzhat ^a   Prasad, Rajendra ^b   Mishra, Vikas ^b  

^a KING GEORGE'S MEDICAL UNIVERSITY   (India)

^b SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

ADAM33 protein expression; Asthma; Bronchial biopsy; Immunohistochemistry; Severity of asthma

Indexed keywords

ADAM PROTEIN; ADAM33 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; ASTHMA; BRONCHOSCOPY; BRONCHUS BIOPSY; CASE CONTROL STUDY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG FUNCTION TEST; MALE; MESENCHYME CELL; PHENOTYPE; PROTEIN EXPRESSION; RESPIRATORY EPITHELIUM; SCORING SYSTEM; SMOOTH MUSCLE FIBER; SPIROMETRY;

ADAM PROTEINS; ADULT; ASTHMA; BIOPSY; BRONCHI; FEMALE; GENE EXPRESSION REGULATION; HUMANS; MALE; MIDDLE AGED; MYOCYTES, SMOOTH MUSCLE; PROSPECTIVE STUDIES;

EID: 84876421243     PISSN: 09715916     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Cookson WO, Moffatt MF. Genetics of asthma and allergic disease. Hum Mol Genet 2000; 9: 2359-64.
2. Global Initiative for Asthma (Gina), National Heart, Lung and Blood Institute, US Department of Health and Human Services: National Institute of Health (NIH) Publication No 02-3659 (2005). Available from: http://www.ginasthma.org/ Guidelines/guidelines-resources.html.
3. Primakoff P, Myles DG. The ADAM gene family: surface proteins with adhesion and protease activity. Trends Genet 2000; 16: 83-7.
4. Yoshinaka T, Nishii K, Yamada K, Sawada H, Nishiwaki E, Smith K, et al. Identification and characterization of novel mouse and human ADAM33s with potential metalloprotease activity. Gene 2002; 282: 227-36.
5. Gunn TM, Azarani A, Kim PH, Hyman RW, Davis RW, Barsh GS. Identification and preliminary characterization of mouse Adam33. BMC Genet 2002; 3: 2.
6. Kawaguchi N, Xu X, Tajima R, Kronqvist P, Sundberg C, Loechel F, et al. ADAM 12 protease induces adipogenesis in transgenic mice. Am J Pathol 2002; 160: 1895-903.
7. Shirakabe K, Wakatsuki S, Kurisaki T, Fujisawa SA. Roles of meltrin beta /ADAM19 in the processing of neuregulin. J Biol Chem 2001; 276: 9352-8.
8. Wolfsberg TG, Straight PD, Gerena RL, Huovila AP, Primakoff P, Myles DG, et al. ADAM, a widely distributed and developmentally regulated gene family encoding membrane proteins with a disintegrin and metalloprotease domain. Dev Biol 1995; 169: 378-83.
9. Alfandari D, Wolfsberg TG, White JM, DeSimone DW. ADAM 13: a novel ADAM expressed in somitic mesoderm and neural crest cells during Xenopus laevis development. Dev Biol 1997; 182: 314-30.
10. Eto K, Puzon-McLaughlin W, Sheppard D, Sehara-Fujisawa A, Zhang XP, Takada Y. RGD-independent binding of integrin alpha9beta1 to the ADAM-12 and-15 disintegrin domains mediates cell-cell interaction. J Biol Chem 2000; 275: 34922-30.
11. Gilpin BJ, Loechel F, Mattei MG, Engvall E, Albrechtsen R, Wewer UM. A novel, secreted form of human ADAM 12 (meltrin alpha) provokes myogenesis in vivo. J Biol Chem 1998; 273: 157-66.
12. Martin J, Eynstone LV, Davies M, Williams JD, Steadman R. The role of ADAM 15 in glomerular mesangial cell migration. J Biol Chem 2002; 277: 33683-9.
13. Yuan R, Primakoff P, Myles DG. A role for the disintegrin domain of cyritestin, a sperm surface protein belonging to the ADAM family, in mouse sperm-egg plasma membrane adhesion and fusion. J Cell Biol 1997; 137: 105-12.
14. White JM. ADAMs: modulators of cell-cell and cell-matrix interactions. Curr Opin Cell Biol. 2003; 15: 598-606.
15. McFarlane S. Metalloproteases: carving out a role in axon guidance. Neuron 2003; 37: 559-62.
16. Hundhausen C, Misztela D, Berkhout TA, Broadway N, Saftig P, Reiss K, et al. The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion. Blood 2003; 102: 1186-95.
17. Seals DF, Courtneidge SA. The ADAMs family of metalloproteases: multidomain proteins with multiple functions. Genes Dev 2003; 17: 7-30.
18. Umland SP, Garlisi CG, Shah H, Wan Y, Zou J, Devito KE, et al. Human ADAM33 messenger RNA expression profile and post-transcriptional regulation. Am J Respir Cell Mol Biol 2003; 29: 571-82.
19. Puxeddu I, Pang YY, Harvey A, Haitchi HM, Nicholas B, Yoshisue H, et al. The soluble form of a disintegrin and metalloprotease 33 promotes angiogenesis: implications for airway remodeling in asthma. J Allergy Clin Immunol 2008; 121: 1400-6.
20. Van Eerdewegh P, Little RD, Dupuis J, Del Mastro RG, Falls K, Simon J, et al. Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness. Nature 2001; 418: 426-30.
21. Sharma N, Tripathi P, Awasthi S, Role of ADAM33 gene and associated single nucleotide polymorphisms in asthma. Allergy Rhinol (Providence) 2011; 2: e63-70.
22. Haitchi HM, Powell RM, Shaw TJ, Howarth PH, Wilson SJ, Wilson DI, et al. ADAM33 expression in asthmatic airways and human embryonic lungs. Am J Respir Crit Care Med 2005; 171: 958-65.
23. Lee JY, Park SW, Chang HK, Kim HY, Rhim T, Lee JH, et al. A disintegrin and metalloproteinase 33 protein in patients with asthma: Relevance to airflow limitation. Am J Respir Crit Care Med 2006; 173: 729-35.
24. Foley SC, Mogas AK, Olivenstein R, Fiset PO, Chakir J, Bourbeau J, et al. Increased expression of ADAM33 and ADAM8 with disease progression in asthma. J Allergy Clin Immunol 2007; 119: 863-71.
25. Lambert RK, Wiggs BR, Kuwano K, Hogg JC, Paré PD. Functional significance of increased airway smooth muscle in asthma and COPD. J Appl Physiol 1993; 74: 2771-81.
26. Miller MR, Crapo R, Hankinson J, Brusasco V, Burgos F, Casaburi R, et al. ATS/ERS Task Force. General considerations for lung function testing. Eur Respir J 2005; 26: 153-61.
27. Davies DE. The role of the epithelium in airway remodeling in asthma. Proc Am Thorac Soc 2009; 6: 678-82.
28. Ito I, Laporte JD, Fiset PO, Asai K, Yamauchi Y, Martin JG, et al. Downregulation of a disintegrin and metalloproteinase 33 by IFN-gamma in human airway smooth muscle cells. J Allergy Clin Immunol 2007; 119: 89-97.
29. Powell RM, Wicks J, Holloway JW, Holgate ST, Davies DE. The splicing and fate of ADAM33 transcripts in primary human airways fibroblasts. Am J Respir Cell Mol Biol 2004; 31: 13-21.
30. Dijkstra A, Postma DS, Noordhoek JA, Lodewijk ME, Kauffman HF, ten Hacken NH, et al. Expression of ADAMs ("a disintegrin and metalloprotease") in the human lung. Virchows Arch 2009; 454: 441-9.
31. Holgate ST, Davies DE, Powell RM, Holloway JW. ADAM33: a newly identified protease involved in airway remodelling. Pulm Pharmacol Ther 2006; 19: 3-11.