Impaired expression of genes involved in the butyrate oxidation pathway in crohn's disease patients

Inflammatory Bowel Diseases

Volumn 19, Issue 3, 2013, Pages

  De Preter, Vicky ^a   Rutgeerts, Paul ^a   Schuit, Frans ^b   Verbeke, Kristin ^a   Arijs, Ingrid ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ACADS PROTEIN; ACAT2 PROTEIN; ACSM3 PROTEIN; BUTYRIC ACID; ECHS1 PROTEIN; HSD17B10 PROTEIN; INFLIXIMAB; INTERLEUKIN 7; INTERLEUKIN 8; MESSENGER RNA; MONOCARBOXYLATE TRANSPORTER 1; PROTEIN; UNCLASSIFIED DRUG;

CLINICAL ARTICLE; COLON BIOPSY; CONTROLLED STUDY; CROHN DISEASE; DRUG RESPONSE; FATTY ACID OXIDATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMAN; HUMAN TISSUE; IMMUNOSUPPRESSIVE TREATMENT; LETTER; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

3-HYDROXYACYL COA DEHYDROGENASES; BIOLOGICAL MARKERS; BUTYRATES; CASE-CONTROL STUDIES; COENZYME A LIGASES; COLON; CROHN DISEASE; DOWN-REGULATION; HUMANS; MONOCARBOXYLIC ACID TRANSPORTERS; OXIDATION-REDUCTION; STEROL O-ACYLTRANSFERASE; SYMPORTERS;

EID: 84876415777     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1002/ibd.22970     Document Type: Letter

References (7)

1. Thibault R, Blachier F, Darcy-Vrillon B, et al. Butyrate utilization by the colonic mucosa in inflammatory bowel diseases: a transport deficienc. Inflamm Bowel Dis. 2010;16:684-695.
2. De Preter V, Bulteel V, Suenaert P, et al. Pouchitis, similar to active ulcerative colitis, is associated with impaired butyrate oxidation by intestinal mucosa. Inflamm Bowel Dis. 2009;15: 335-340.
3. De Preter V, Arijs I, Windey K, et al. Impaired butyrate oxidation in ulcerative colitis is due to decreased butyrate uptake and a defect in the oxidation pathway. Inflamm Bowel Dis. 2012;18:1127-1136.
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