Characteristics of polyomavirus BK (BKPyV) infection in primary human urothelial cells

Virology

Volumn 440, Issue 1, 2013, Pages 41-50

  Li, Ruomei ^a,b   Sharma, Biswa Nath ^a,b   Linder, Stig ^c   Gutteberg, Tore Jarl ^a,b   Hirsch, Hans H ^d,e   Rinaldo, Christine Hanssen ^a,b  

^a UNIVERSITY HOSPITAL OF NORTH NORWAY   (Norway)

^b UNIVERSITY OF TROMSØ   (Norway)

^c KAROLINSKA INSTITUTE   (Sweden)

^d UNIVERSITY OF BASEL   (Switzerland)

^e UNIVERSITY HOSPITAL BASEL   (Switzerland)

Author keywords

BK virus; BKPyV; Hemorrhagic cystitis; Human; Nephropathy; Polyomavirus; Renal tubular epithelial cells; Replication; Transplantation; Urothelial cells

Indexed keywords

AGNOPROTEIN; CYTOKERATIN 18; PROTEIN VP 1 3; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS T ANTIGEN;

ARTICLE; CELL NUCLEUS; CELL STRUCTURE; CELL TYPE; CELL VIABILITY; CONTROLLED STUDY; EPITHELIUM CELL; HUMAN; HUMAN CELL; HUMAN UROTHELIAL CELL; KIDNEY TUBULE CELL; MOLECULAR IMAGING; POLYOMAVIRUS BK INFECTION; POLYOMAVIRUS INFECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; VIRION; VIRUS CELL INTERACTION; VIRUS REPLICATION;

BK VIRUS; CELL NUCLEUS; CELLS, CULTURED; EPITHELIAL CELLS; GENE EXPRESSION REGULATION, VIRAL; HUMANS; KIDNEY TUBULES; UROTHELIUM; VIRAL PROTEINS; VIRUS CULTIVATION; VIRUS REPLICATION;

BK POLYOMAVIRUS; POLYOMAVIRUS;

EID: 84876408423     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2013.01.024     Document Type: Article

References (41)

1. Abend J.R., Joseph A.E., Das D., Campbell-Cecen D.B., Imperiale M.J. A truncated T antigen expressed from an alternatively spliced BK virus early mRNA. J. Gen. Virol. 2009, 90:1238-1245.
2. Arthur R.R., Shah K.V., Baust S.J., Santos G.W., Saral R. Association of BK viruria with hemorrhagic cystitis in recipients of bone marrow transplants. N. Engl. J. Med. 1986, 315:230-234.
3. Azzi A., Cesaro S., Laszlo D., Zakrzewska K., Ciappi S., de Santis R., Fanci R., Pesavento G., Calore E., Bosi A. Human polyomavirus BK (BKV) load and haemorrhagic cystitis in bone marrow transplantation patients. J. Clin. Virol. 1999, 14:79-86.
4. Beckmann A.M., Shah K.V. Propagation and primary isolation of JCV and BKV in urinary epithelial cell cultures. Prog. Clin. Biol. Res. 1983, 105:3-14.
5. Bedi A., Miller C.B., Hanson J.L., Goodman S., Ambinder R.F., Charache P., Arthur R.R., Jones R.J. Association of BK virus with failure of prophylaxis against hemorrhagic cystitis following bone marrow transplantation. J. Clin. Oncol. 1995, 13:1103-1109.
6. Bernhoff E., Gutteberg T.J., Sandvik K., Hirsch H.H., Rinaldo C.H. Cidofovir inhibits polyomavirus BK replication in human renal tubular cells downstream of viral early gene expression. Am. J. Transplant. 2008, 8:1413-1422.
7. Bernhoff E., Tylden G.D., Kjerpeseth L.J., Gutteberg T.J., Hirsch H.H., Rinaldo C.H. Leflunomide inhibition of BK virus replication in renal tubular epithelial cells. J. Virol. 2010, 84:2150-2156.
8. Binet I., Nickeleit V., Hirsch H.H. Polyomavirus infection in transplant recipients. Curr. Opin. Organ Transplant. 2000, 5:210-216.
9. Chesters P.M., Heritage J., McCance D.J. Persistence of DNA sequences of BK virus and JC virus in normal human tissues and in diseased tissues. J. Infect. Dis. 1983, 147:676-684.
10. Cole C.N. Polyomavirinae: the viruses and their replication. Fields Virology 1996, 1997-2025. Lippincott-Raven Publisher, Philadelphia. B.N. Fields, D.M. Knipe, P.M. Howley (Eds.).
11. Dropulic L.K., Jones R.J. Polyomavirus BK infection in blood and marrow transplant recipients. Bone Marrow Transplant. 2008, 41:11-18.
12. Dunai Z.A., Imre G., Barna G., Korcsmaros T., Petak I., Bauer P.I., Mihalik R. Staurosporine induces necroptotic cell death under caspase-compromised conditions in U937 cells. PloS One 2012, 7:e41945.
13. Egli A., Infanti L., Dumoulin A., Buser A., Samaridis J., Stebler C., Gosert R., Hirsch H.H. Prevalence of polyomavirus BK and JC infection and replication in 400 healthy blood donors. J. Infect. Dis. 2009, 199:837-846.
14. Felix J.S., Sun T.T., Littlefield J.W. Human epithelial cells cultured from urine: growth properties and keratin staining. In Vitro 1980, 16:866-874.
15. Funk G.A., Gosert R., Comoli P., Ginevri F., Hirsch H.H. Polyomavirus BK replication dynamics in vivo and in silico to predict cytopathology and viral clearance in kidney transplants. Am. J. Transplant. 2008, 8:2368-2377.
16. Gardner S.D., Field A.M., Coleman D.V., Hulme B. New human papovavirus (B.K.) isolated from urine after renal transplantation. Lancet 1971, 1:1253-1257.
17. Giraud G., Bogdanovic G., Priftakis P., Remberger M., Svahn B.M., Barkholt L., Ringden O., Winiarski J., Ljungman P., Dalianis T. The incidence of hemorrhagic cystitis and BK-viruria in allogeneic hematopoietic stem cell recipients according to intensity of the conditioning regimen. Haematologica 2006, 91:401-404.
18. Hey A.W., Johnsen J.I., Johansen B., Traavik T. A two fusion partner system for raising antibodies against small immunogens expressed in bacteria. J. Immunol. Methods 1994, 173:149-156.
19. Hirsch H.H. Polyoma and papilloma virus infections after hematopoietic stem cell or solid organ transplantation. Transplant Infections 2010, 465-482. Lippincott Williams & Wilkins. P. Bowden, P. Ljungman, D.R. Snydman (Eds.).
20. Hirsch H.H., Knowles W., Dickenmann M., Passweg J., Klimkait T., Mihatsch M.J., Steiger J. Prospective study of polyomavirus type BK replication and nephropathy in renal-transplant recipients. N. Engl. J. Med 2002, 347:488-496.
21. Hirsch H.H., Mohaupt M., Klimkait T. Prospective monitoring of BK virus load after discontinuing sirolimus treatment in a renal transplant patient with BK virus nephropathy. J. Infect. Dis. 2001, 184:1494-1496.
22. Hirsch H.H., Randhawa P. BK virus in solid organ transplant recipients. Am. J. Transplant. 2009, 9(4):S136-S146.
23. Hirsch, H.H. and Randhawa, P. and the AST Infectious Diseases Community of Practice, 2013. American Society of Transplantation Infectious Disease Community of Practice Guidelines: BK Polyomavirus Update 2012. Am. J. Transplant 13: 179-188.
24. Hirsch H.H., Steiger J. Polyomavirus BK. Lancet Infect. Dis. 2003, 3:611-623.
25. Jiang M., Zhao L., Gamez M., Imperiale M.J. Roles of ATM and ATR-mediated DNA damage responses during lytic BK polyomavirus infection. PLoS Pathogens 2012, 8:e1002898.
26. Jost S.P., Gosling J.A., Dixon J.S. The morphology of normal human bladder urothelium. J. Anat. 1989, 167:103-115.
27. Kling C.L., Wright A.T., Katz S.E., McClure G.B., Gardner J.S., Williams J.T., Meinerz N.M., Garcea R.L., Vanchiere J.A. Dynamics of urinary polyomavirus shedding in healthy adult women. J. Med. Virol. 2012, 84:1459-1463.
28. Knowles M.A., Finesilver A., Harvey A.E., Berry R.J., Hicks R.M. Long-term organ culture of normal human bladder. Cancer Res. 1983, 43:374-385.
29. Knowles W.A. Discovery and epidemiology of the human polyomaviruses BK virus (BKV) and JC virus (JCV). Adv. Exp. Med. Biol. 2006, 577:19-45.
30. Leung A.Y., Suen C.K., Lie A.K., Liang R.H., Yuen K.Y., Kwong Y.L. Quantification of polyoma BK viruria in hemorrhagic cystitis complicating bone marrow transplantation. Blood 2001, 98:1971-1978.
31. Low J., Humes H.D., Szczypka M., Imperiale M. BKV and SV40 infection of human kidney tubular epithelial cells in vitro. Virology 2004, 323:182-188.
32. McDowell E.M., Trump B.F. Histologic fixatives suitable for diagnostic light and electron microscopy. Arch. Pathol. Lab. Med. 1976, 100:405-414.
33. Nickeleit V., Hirsch H.H., Binet I.F., Gudat F., Prince O., Dalquen P., Thiel G., Mihatsch M.J. Polyomavirus infection of renal allograft recipients: from latent infection to manifest disease. J. Am. Soc. Nephrol. 1999, 10:1080-1089.
34. Orba Y., Suzuki T., Makino Y., Kubota K., Tanaka S., Kimura T., Sawa H. Large T antigen promotes JC virus replication in G2-arrested cells by inducing ATM- and ATR-mediated G2 checkpoint signaling. J. Biol. Chem. 2010, 285:1544-1554.
35. Polo C., Perez J.L., Mielnichuck A., Fedele C.G., Niubo J., Tenorio A. Prevalence and patterns of polyomavirus urinary excretion in immunocompetent adults and children. Clin. Microbiol. Infect. 2004, 10:640-644.
36. Rinaldo C.H., Gosert R., Bernhoff E., Finstad S., Hirsch H.H. 1-O-hexadecyloxypropyl cidofovir (CMX001) effectively inhibits polyomavirus BK replication in primary human renal tubular epithelial cells. Antimicrob. Agents Chemother. 2010, 54:4714-4722.
37. Rinaldo C.H., Myhre M.R., Alstad H., Nilssen O., Traavik T. Human polyomavirus BK (BKV) transiently transforms and persistently infects cultured osteosarcoma cells. Virus Res. 2003, 93:181-187.
38. Rinaldo C.H., Traavik T., Hey A. The agnogene of the human polyomavirus BK is expressed. J. Virol. 1998, 72:6233-6236.
39. Sack G.H., Felix J.S., Lanahan A.A. Plaque formation and purification of BK virus in cultured human urinary cells. J. Gen. Virol. 1980, 50:185-189.
40. Sharma B.N., Li R., Bernhoff E., Gutteberg T.J., Rinaldo C.H. Fluoroquinolones inhibit human polyomavirus BK (BKV) replication in primary human kidney cells. Antiviral Res. 2011, 92:115-123.
41. Wu X.R., Kong X.P., Pellicer A., Kreibich G., Sun T.T. Uroplakins in urothelial biology, function, and disease. Kidney Int. 2009, 75:1153-1165.