The role of cytokines in diabetic foot osteomyelitis

Diabetic Medicine

Volumn 30, Issue 5, 2013, Pages 628-629

  Aragon Sanchez J ^a   Cabrera Galvan J J ^b,c  

^a Endoluminal Therapy   (Spain)

^b La Paloma Hospital   (Spain)

^c UNIVERSITY OF LAS PALMAS DE GRAN CANARIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; BONE MARROW; CYTOKINE RELEASE; DIABETIC FOOT; FIBROBLAST; HUMAN; IMMUNOHISTOCHEMISTRY; LETTER; LYMPHOCYTE; MACROPHAGE; MONOCYTE; NEUTROPHIL; NONHUMAN; OSTEOBLAST; OSTEOCLAST; OSTEOCYTE; OSTEOLYSIS; OSTEOMYELITIS; QUANTITATIVE ANALYSIS; RETROSPECTIVE STUDY; STAPHYLOCOCCUS AUREUS;

CYTOKINES; DIABETIC FOOT; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-6; MALE; OSTEOMYELITIS; RETROSPECTIVE STUDIES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84876389055     PISSN: 07423071     EISSN: 14645491     Source Type: Journal    
DOI: 10.1111/dme.12114     Document Type: Letter

References (8)

1. Littlewood-Evans AJ, Hattenberger MR, Luscher C, Pataki A, Zak O, O'Reilly T. Local expression of tumor necrosis factor alpha in an experimental model of acute osteomyelitis in rats. Infect Immun 1997; 65: 3438-3443.
2. Fullilove S, Jellis J, Hughes SP, Remick DG, Friedland JS. Local and systemic concentrations of tumour necrosis factor-alpha, interleukin-6 and interleukin-8 in bacterial osteomyelitis. Trans R Soc Trop Med Hyg 2000; 94: 221-224.
3. Aragon-Sanchez FJ, Cabrera-Galvan JJ, Quintana-Marrero Y, Hernandez-Herrero MJ, Lazaro-Martinez JL, Garcia-Morales E et al. Outcomes of surgical treatment of diabetic foot osteomyelitis: a series of 185 patients with histopathological confirmation of bone involvement. Diabetologia 2008; 51: 1962-1970.
4. Marriott I, Gray DL, Tranguch SL, Fowler VG Jr, Stryjewski M, Scott Levin L et al. Osteoblasts express the inflammatory cytokine interleukin-6 in a murine model of Staphylococcus aureus osteomyelitis and infected human bone tissue. Am J Pathol 2004; 164: 1399-1406.
5. Ning R, Zhang X, Guo X, Li Q. Staphylococcus aureus regulates secretion of interleukin-6 and monocyte chemoattractant protein-1 through activation of nuclear factor kappaB signaling pathway in human osteoblasts. Braz J Infect Dis 2011; 15: 189-194.
6. Asensi V, Valle E, Meana A, Fierer J, Celada A, Alvarez V et al. In vivo interleukin-6 protects neutrophils from apoptosis in osteomyelitis. Infect Immun 2004; 72: 3823-3828.
7. Yoshii T, Magara S, Miyai D, Nishimura H, Kuroki E, Furudoi S et al. Local levels of interleukin-1beta, -4, -6 and tumor necrosis factor alpha in an experimental model of murine osteomyelitis due to staphylococcus aureus. Cytokine 2002; 19: 59-65.
8. Jeffcoate WJ, Game F, Cavanagh PR. The role of proinflammatory cytokines in the cause of neuropathic osteoarthropathy (acute Charcot foot) in diabetes. Lancet 2005; 366: 2058-2061.