The never-ending story of angiotensin peptides: Beyond angiotensin i and II

Circulation Research

Volumn 112, Issue 8, 2013, Pages 1086-1087

  Dell'Italia, Louis J ^a,b   Ferrario, Carlos M ^c  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

alamandine; angiotensin converting enzyme; Editorial; renin angiotensin system

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ANGIOTENSIN CONVERTING ENZYME 2; ANGIOTENSIN I; ANGIOTENSIN II; ANGIOTENSIN III; ANGIOTENSIN[1-7]; ANGIOTENSINOGEN; CARBOXYLASE; DIPEPTIDYL CARBOXYPEPTIDASE; G PROTEIN COUPLED RECEPTOR; RENIN;

AMINO ACID COMPOSITION; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; BIOTRANSFORMATION; DECARBOXYLATION; EDITORIAL; GENE MUTATION; HUMAN; KIDNEY FAILURE; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN CLEAVAGE; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SPINAL GANGLION; VASODILATATION;

ANGIOTENSIN I; ANIMALS; ANTIHYPERTENSIVE AGENTS; DRUG DISCOVERY; HUMANS; MALE; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; RENIN-ANGIOTENSIN SYSTEM;

EID: 84876355175     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.113.301246     Document Type: Editorial

References (18)

1. Lautner RQ, Villela DC, Fraga-Silva RA, et al. Discovery and characterization of alamandine, a novel component of the renin-angiotensin system. Circ Res. 2013;112:1104-1111.
2. Ferrario CM. New physiological concepts of the renin-angiotensin system from the investigation of precursors and products of angiotensin I metabolism. Hypertension. 2010;55:445-452.
3. Santos RA, Simoes E Silva AC, Maric C, et al. Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Proc Natl Acad Sci USA. 2003;100(14):8258-8263.
4. Crackower MA, Sarao R, Oudit GY, et al. Angiotensin-converting enzyme 2 is an essential regulator of heart function. Nature. 2002;417:822-828.
5. Ferrario CM, Varagic J, Habibi J, Nagata S, Kato J, Chappell MC, Trask AJ, Kitamura K, Whaley-Connell A, Sowers JR. Differential regulation of angiotensin-(1-12) in plasma and cardiac tissue in response to bilateral nephrectomy. Am J Physiol Heart Circ Physiol. 2009;296:H1184-H1192.
6. Nagata S, Kato J, Sasaki K, Minamino N, Eto T, Kitamura K. Isolation and identifcation of proangiotensin-12, a possible component of the renin-an-giotensin system. Biochem Biophys Res Commun. 2006;350:1026-1031.
7. Ahmad S, Simmons T, Varagic J, Moniwa N, Chappell MC, Ferrario CM. Chymase-dependent generation of angiotensin II from angiotensin-(1-12) in human atrial tissue. PLoS One. 2011;6:e28501.
8. Ahmad S, Wei CC, Tallaj J, Dell'italia LJ, Moniwa N, Varagic J, Ferrario CM. Chymase mediates angiotensin-(1-12) metabolism in normal human hearts. J Am Soc Hypertens 2013;7:28-136.
9. Belova LA. Angiotensin II-generating enzymes. Biochemistry Mosc. 2000;65:1337-1345.
10. Boucher R, Demassieux S, Garcia R, Genest J. Tonin, angiotensin II system: a review. Circ Res. 1977;41:26-29.
11. Hackenthal E, Hackenthal R, Hilgenfeldt U. Isorenin, pseudorenin, cathepsin D and renin: a comparative enzymatic study of angiotensin-forming enzymes. Biochim Biophys Acta. 1978;522:574-588.
12. Holloway AC, Qian H, Pipolo L, Ziogas J, Miura S, Karnik S, Southwell BR, Lew MJ, Thomas WG. Side-chain substitutions within an-giotensin II reveal different requirements for signaling, internalization, and phosphorylation of type 1A angiotensin receptors. Mol Pharmacol. 2002; 61:768-777.
13. Valloton MB. Immunogenicity and antigenicity of angiotensin I and II. In: Page IH, Bumpus IH, eds. Angiotensin. Heidelberg, Germany: SpringerVerlag Berlin; 1974:185-200.
14. Crozier RA, Ajit SK, Kaftan EJ, Pausch MH. MrgD activation inhibits KCNQ/M-currents and contributes to enhanced neuronal excitability. J Neurosci. 2007;27:4492-4496.
15. Gembardt F, Grajewski S, Vahl M, Schultheiss HP, Walther T. Angiotensin metabolites can stimulate receptors of the Mas-related genes family. Mol Cell Biochem. 2008;319:115-123.
16. Husain A, Bumpus FM, Smeby RR, Brosnihan KB, Khosla MC, Speth RC, Ferrario CM. Evidence for the existence of a family of biologically active angiotensin I-like peptides in the dog central nervous system. Circ Res. 1983;52:460-464.
17. Ahmad S, Varagic J, Westwood BM, Chappell MC, Ferrario CM. Uptake and metabolism of the novel peptide angiotensin-(1-12) by neonatal cardiac myocytes. PLoS One. 2011;6:e15759.
18. Jessup JA, Trask AJ, Chappell MC, Nagata S, Kato J, Kitamura K, Ferrario CM. Localization of the novel angiotensin peptide, angiotensin-(1-12), in heart and kidney of hypertensive and normotensive rats. Am J Physiol Heart Circ Physiol. 2008;294:H2614-H2618.