Schistosomiasis and impaired response to antiretroviral therapy among HIV-infected patients in Tanzania

Journal of Acquired Immune Deficiency Syndromes

Volumn 62, Issue 5, 2013, Pages

  Efraim, Lucheri ^a,b   Peck, Robert N ^a,b,c   Kalluvya, Samuel E ^a,b   Kabangila, Rodrick ^a,b   Mazigo, Humphrey D ^a   Mpondo, Boniventura ^a,b,d   Bang, Heejung ^e,f   Todd, James ^c   Fitzgerald, Daniel W ^c   Downs, Jennifer A ^b,c  

^a CATHOLIC UNIVERSITY OF HEALTH AND ALLIED SCIENCES   (Tanzania)

^b Bugando Medical Centre   (Tanzania)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d UNIVERSITY OF DODOMA   (Tanzania)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; PRAZIQUANTEL;

ADULT; BODY MASS; CD4 LYMPHOCYTE COUNT; CONTROLLED STUDY; DEMOGRAPHY; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE ASSOCIATION; DRUG EFFICACY; DRUG SAFETY; EPIDEMIC; FECES CULTURE; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFORMED CONSENT; LETTER; MAJOR CLINICAL STUDY; MALE; PREVALENCE; PRIORITY JOURNAL; RISK FACTOR; SCHISTOSOMIASIS; SENSITIVITY AND SPECIFICITY; TANZANIA; TREATMENT OUTCOME; TREATMENT RESPONSE; URINALYSIS;

ADULT; ANIMALS; ANTI-HIV AGENTS; CD4 LYMPHOCYTE COUNT; COHORT STUDIES; FECES; FEMALE; HIV; HIV INFECTIONS; HUMANS; LOGISTIC MODELS; MALE; PARASITE EGG COUNT; RETROSPECTIVE STUDIES; SCHISTOSOMA; SCHISTOSOMIASIS; TANZANIA;

EID: 84876350380     PISSN: 15254135     EISSN: 10779450     Source Type: Journal    
DOI: 10.1097/QAI.0b013e318282a1a4     Document Type: Letter

References (19)

1. World Health Organization. Schistosomiasis, Fact Sheet No. 115. Available at: http://www.who.int/mediacentre/factsheets/fs115/en/index.html. Accessed October 09, 2012.
2. Bentwich Z, Maartens G, Torten D, et al. Concurrent infections and HIV pathogenesis. AIDS. 2000;14:2071-2081.
3. Joseph S, Jones FM, Laidlaw ME, et al. Impairment of the Schistosoma mansoni-specific immune responses elicited by treatment with praziquantel in Ugandans with HIV-1 coinfection. J Infect Dis. 2004;190:613-618.
4. Bentwich Z, Kalinkovich A, Weisman Z. Immune activation is a dominant factor in the pathogenesis of African AIDS. Immunol Today. 1995;16: 187-191.
5. Kullberg MC, Pearce EJ, Hieny SE, et al. Infection with Schistosoma mansoni alters Th1/Th2 cytokine responses to a non-parasite antigen. J Immunol. 1992;148:3264-3270.
6. Elliott AM, Mawa PA, Joseph S, et al. Associations between helminth infection and CD4+ T cell count, viral load and cytokine responses in HIV-1-infected Ugandan adults. Trans R Soc Trop Med Hyg. 2003;97:103-108.
7. Clerici M, Shearer GM. A TH1-.TH2 switch is a critical step in the etiology of HIV infection. Immunol Today. 1993;14:107-111.
8. Walson JL, Otieno PA, Mbuchi M, et al. Albendazole treatment of HIV-1 and helminth co-infection: a randomized, double-blind, placebo- controlled trial. AIDS. 2008;22:1601- 1609.
9. Nielsen NO, Simonsen PE, Dalgaard P, et al. Effect of diethylcarbamazine on HIV load, CD4%, and CD4/CD8 ratio in HIV-infected adult Tanzanians with or without lymphatic filariasis: randomized double-blind and placebo- controlled cross-over trial. Am J Trop Med Hyg. 2007;77:507-513.
10. Kallestrup P, Zinyama R, Gomo E, et al. Schistosomiasis and HIV-1 infection in rural Zimbabwe: effect of treatment of schistosomiasis on CD4 cell count and plasma HIV-1 RNA load. J Infect Dis. 2005;192:1956-1961.
11. World Health Organization. Antiretroviral Therapy for HIV Infection in Adults and Adolescents. 2010 revision. Geneva, Switzerland: World Health Organization Press. 2010. Available at: http://whqlibdoc.who.int/publications/ 2010/9789241599764-eng.pdf. Accessed January 31, 2012.
12. Berhe N, Medhin G, Erko B, et al. Variations in helminth faecal egg counts in Kato-Katz thick smears and their implications in assessing infection status with Schistosoma mansoni. Acta Trop. 2004;92:205-212.
13. Deelder AM, De Jonge N, Fillie YE, et al. Quantitative determination of circulating antigens in human schistosomiasis mansoni using an indirect hemagglutination assay. Am J Trop Med Hyg. 1989;40:50-54.
14. van Etten L, Folman CC, Eggelte TA, et al. Rapid diagnosis of schistosomiasis by antigen detection in urine with a reagent strip. J Clin Microbiol. 1994;32:2404-2406.
15. Van Lieshout L, Panday UG, De Jonge N, et al. Immunodiagnosis of schistosomiasis mansoni in a low endemic area in Surinam by determination of the circulating antigens CAA and CCA. Acta Trop. 1995; 59:19-29.
16. Vickers AJ, Altman DG. Statistics notes: analysing controlled trials with baseline and follow up measurements. BMJ. 2001;323: 1123-1124.
17. Walson J, Singa B, Sangare L. Empiric deworming to delay HIV disease progression in adults with HIV who are ineligible for initiation of antiretroviral treatment (the HEAT study): a multi-site, randomised trial. Lancet Infect Dis. 2012;12:925-932.
18. Fontanet AL, Woldemichael T, Sahlu T, et al. Epidemiology of HIV and Schistosoma mansoni infections among sugar-estate residents in Ethiopia. Ann Trop Med Parasitol. 2000;94: 145-155.
19. Karanja DM, Colley DG, Nahlen BL, et al. Studies on schistosomiasis in western Kenya: I. Evidence for immune-facilitated excretion of schistosome eggs from patients with Schistosoma mansoni and human immunodeficiency virus coinfections. Am J Trop Med Hyg. 1997;56:515-521.