Identification of the interaction between P-Glycoprotein and Anxa2 in multidrug-resistant human breast cancer cells

Cancer Biology and Medicine

Volumn 9, Issue 2, 2012, Pages 99-104

  Zhang, Hai Chang ^a   Zhang, Fei ^a   Wu, Bing ^a   Han, Jing Hua ^a   Ji, Wei ^a   Zhou, Yan ^a   Niu, Rui Fang ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Anxa2; Breast neoplasm; Drug resistance; Multiple; Neoplasm metastasis; P glycoprotein

Indexed keywords

ANXA2 PROTEIN; DOXORUBICIN; MEMBRANE PROTEIN; MULTIDRUG RESISTANCE PROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL; CELL CLONE; CELL INVASION; CELL LINE; CELL MIGRATION; CELL STRAIN ADR; CELL STRAIN MCF 7; CONFOCAL MICROSCOPY; DOWN REGULATION; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; MULTIDRUG RESISTANT BREAST CANCER; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; WESTERN BLOTTING;

EID: 84876333083     PISSN: 20953941     EISSN: None     Source Type: Journal    
DOI: 10.3969/j.issn.2095-3941.2012.02.003     Document Type: Article

References (14)

1. Yang JM, Xu Z, Wu H, et al. Overexpression of extracellular matrix metalloproteinase inducer in multidrug resistant cancer cells. Mol Cancer Res 2003; 1: 420-427.
2. Reimers N, Zafrakas K, Assmann V, et al. Expression of extracellular matrix metalloproteases inducer on micrometastatic and primary mammary carcinoma cells. Clin Cancer Res 2004; 10: 3422-3428.
3. Marieb EA, Zoltan-Jones A, Li R, et al. Emmprin promotes anchorage-independent growth in human mammary carcinoma cells by stimulating hyaluronan production. Cancer Res 2004; 64: 1229-1232.
4. Miletti-González KE, Chen S, Muthukumaran N, et al. The CD44 receptor interacts with P-glycoprotein to promote cell migration and invasion in cancer. Cancer Res 2005; 65: 6660-6667.
5. Bajorath J, Greenfield B, Munro SB, et al. Identification of CD44 residues important for hyaluronan binding and delineation of the binding site. J Biol Chem 1998; 273: 338-343.
6. Bosch I, Croop J. P-glycoprotein multidrug resistance and cancer. Biochim Biophys Acta 1996; 1288: F37-54.
7. Zhang F, Zhang L, Zhang B, et al. Anxa2 plays a critical role in enhanced invasiveness of the multidrug resistant human breast cancer cells. J Proteome Res 2009; 8: 5041-5047.
8. Endicott JA, Ling V. The biochemistry of P-glycoprotein-mediated multidrug resistance. Annu Rev Biochem 1989; 58: 137-171.
9. Gottesman MM, Pastan I. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem 1993; 62: 385-427.
10. Ford JM, Hait WN. Pharmacology of drugs that alter multidrug resistance in cancer. Pharmacol Rev 1990; 42: 155-199.
11. Thompson EW, Paik S, Brunner N, et al. Association of increased basement membrane invasiveness with absence of estrogen receptor and expression of vimentin in human breast cancer cell lines. J Cell Physiol 1992; 150: 534-544.
12. dit Faute MA, Laurent L, Ploton D, et al. Distinctive alterations of invasiveness, drug resistance and cell-cell organization in 3D-cultures of MCF-7, a human breast cancer cell line, and its multidrug resistant variant. Clin Exp Metastasis 2002; 19: 161-168.
13. Fletcher JI, Haber M, Henderson MJ, et al. ABC transporters in cancer: More than just drug efflux pumps. Nat Rev Cancer 2010; 10: 147-156.
14. Lokman NA, Ween MP, Oehler MK, et al. The role of annexin A2 in tumorigenesis and cancer progression. Cancer Microenviron 2011; 4: 199-208.