Chiral analytical method development and application to pre-clinical pharmacokinetics of pinocembrin

Biomedical Chromatography

Volumn 27, Issue 6, 2013, Pages 681-684

  Sayre, Casey L ^a   Takemoto, Jody K ^b   Martinez, Stephanie E ^a   Davies, Neal M ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

^b UNIVERSITY OF HAWAII   (United States)

Author keywords

Chiral; Mass spectrometry; Pharmacokinetics; Pinocembrin; Reversed phase HPLC

Indexed keywords

BODY FLUIDS; ELECTROSPRAY IONIZATION; ENANTIOMERS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; RATS;

ANALYTICAL METHOD; ANALYTICAL METHOD DEVELOPMENT; CHIRAL; CLINICAL PHARMACOKINETICS; DETECTION AND QUANTIFICATIONS; DEVELOPMENT AND APPLICATIONS; HALF LIVES; PINOCEMBRIN; PRE-CLINICAL; REVERSED PHASE HPLC;

PHARMACOKINETICS;

PINOCEMBRINE;

ACCURACY; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CHIRALITY; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG SCREENING; ELECTROSPRAY; ENANTIOMER; LINEAR SYSTEM; NONHUMAN; PROCESS DEVELOPMENT; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SERUM; STEREOCHEMISTRY; VALIDATION STUDY;

RATTUS;

EID: 84876328661     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.2853     Document Type: Article

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