Biological functions of natural antisense transcripts

BMC Biology

Volumn 11, Issue , 2013, Pages

  Werner, Andreas ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; MESSENGER RNA;

ARTICLE; GENETICS; HUMAN; PHYSIOLOGY;

HUMANS; OLIGONUCLEOTIDES, ANTISENSE; RNA, MESSENGER;

MLCS; MLOWN;

EID: 84876315713     PISSN: None     EISSN: 17417007     Source Type: Journal    
DOI: 10.1186/1741-7007-11-31     Document Type: Note

References (11)

1. Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B. Antisense transcription in the mammalian transcriptome. Science 2005, 309:1564-1566.
2. Beiter T, Reich E, Williams RW, Simon P. Antisense transcription: a critical look in both directions. Cell Mol Life Sci 2008, 66:94-112.
3. Ling MHT, Ban Y, Wen H, Wang SM, Ge SX. Conserved expression of natural antisense transcripts in mammals. BMC Genomics 2013, 14:243.
4. Faghihi MA, Wahlestedt C. Regulatory roles of natural antisense transcripts. Nat Rev Mol Cell Biol 2009, 10:637-643. 10.1038/nrm2738, 2850559, 19638999.
5. Tufarelli C, Stanley JA, Garrick D, Sharpe JA, Ayyub H, Wood WG, Higgs DR. Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease. Nat Genet 2003, 34:157-165. 10.1038/ng1157, 12730694.
6. Yu W, Gius D, Onyango P, Muldoon-Jacobs K, Karp J, Feinberg AP, Cui H. Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA. Nature 2008, 451:202-206. 10.1038/nature06468, 2743558, 18185590.
7. Faghihi MA, Zhang M, Huang J, Modarresi F, Van der Brug MP, Nalls MA, Cookson MR, St-Laurent G, Wahlestedt C. Evidence for natural antisense transcript-mediated inhibition of microRNA function. Genome Biol 2010, 11:R56. 10.1186/gb-2010-11-5-r56, 2898074, 20507594.
8. Uchida T, Rossignol F, Matthay MA, Mounier R, Couette S, Clottes E, Clerici C. Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: implication of natural antisense HIF-1alpha. J Biol Chem 2004, 279:14871-14878. 10.1074/jbc.M400461200, 14744852.
9. Carlile M, Swan D, Jackson K, Preston-Fayers K, Ballester B, Flicek P, Werner A. Strand selective generation of endo-siRNAs from the Na/phosphate transporter gene Slc34a1 in murine tissues. Nucleic Acids Res 2009, 37:2274-2282. 10.1093/nar/gkp088, 2673434, 19237395.
10. Chen J, Sun M, Hurst LD, Carmichael GG, Rowley JD. Genome-wide analysis of coordinate expression and evolution of human cis-encoded sense-antisense transcripts. Trends Genet 2005, 21:326-329. 10.1016/j.tig.2005.04.006, 15922830.
11. Werner A, Carlile M, Swan D. What do natural antisense transcripts regulate?. RNA Biol 2009, 6:43-48. 10.4161/rna.6.1.7568, 19098462.