Rac1 GTPase acts downstream of αPS1βPS integrin to control collective migration and lumen size in the Drosophila salivary gland

Developmental Biology

Volumn 377, Issue 1, 2013, Pages 21-32

  Pirraglia, Carolyn ^a   Walters, Jenna ^a   Ahn, Nancy ^a   Myat, Monn Monn ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Adhesion; Cadherin; Collective migration; Drosophila; Integrin; Lumen; Rac GTPase; Tube

Indexed keywords

ALPHAPS1BETAPS INTEGRIN; INTEGRIN; RAC1 PROTEIN; RAC2 PROTEIN; UNCLASSIFIED DRUG; UVOMORULIN;

ADHESION; ANIMAL CELL; ARTICLE; BASEMENT MEMBRANE; CELL MIGRATION; CELL SHAPE; CONTROLLED STUDY; DOWN REGULATION; DROSOPHILA; EMBRYO; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN SYNTHESIS INHIBITION; SALIVARY GLAND;

EID: 84876308745     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2013.02.020     Document Type: Article

References (29)

1. Boube M., Martin-Bermudo M.D., Brown N.H., Casanova J. Specific tracheal migration is mediated by complementary expression of cell surface proteins. Genes Dev. 2001, 15:1554-1562.
2. Bradley P.L., Myat M.M., Comeaux C.A., Andrew D.J. Posterior migration of the salivary gland requires an intact visceral mesoderm and integrin function. Dev. Biol. 2003, 257:249-262.
3. Chihara T., Kato K., Taniguchi M., NG J., Hayashi S. Rac promotes epithelial cell rearrangement during tracheal tubulogenesis in Drosophila. Development 2003, 130:1419-1428.
4. Dominguez-Gimenez P., Brown N.H., Martin-Bermudo M. Integrin-ECM interactions regulate the changes in cell shape driving the morphogenessi of the Drosophila wing epithelium. J. Cell Sci. 2007, 120:1061-1071.
5. Ferguson S., De Camilli P. Dynamin, a membrane-remodelling GTPase. Nat. Rev. Mol. Cell Biol. 2012, 13:75-88.
6. Fox D.T., Homem C.C., Myster S.H., Wang F., Bain E.E., Peifer M. Rho1 regulates Drosophila adherens junctions independently of p120ctn. J. Cell Biol. 2005, 132:4819-4831.
7. Friedl P., Gilmour D. Collective cell migration in morphogenesis, regeneration and cancer. Nat. Rev. Mol. Cell Biol. 2009, 10:445-457.
8. Hall A. Rho GTPases and the control of cell behaviour. Biochem. Soc. Trans. 2005, 33:891-895.
9. Henderson K.D., Andrew D.J. Regulation and function of Scr, exd, and hth in the Drosophila salivary gland. Dev. Biol. 2000, 217:362-374.
10. Jang A.-C., Starz-Gaiano M., Montell D. Modeling migration and metastasis in Drosophila. J. Mammary Gland Biol. Neoplasia 2007, 12:103-114.
11. Maruyama R., Andrew D. Drosophila as model for epithelial tube formation. Dev. Dyn. 2012, 241:119-135.
12. Migeotte I., Omelchenko T., Hall A., Anderson K. Rac1-dependent collective cell migration is required for specification of the anterior-posterior body axis of the mouse. PLoS Biol. 2010, 8:e1000442.
13. Montell D. Morphogenetic cell movements: diversity from modular mechanical properties. Science 2008, 322:1502-1505.
14. Murphy A., Montell D. Cell type-specific roles for Cdc42, Rac, and RhoL in Drosophila oogenesis. J. Cell Biol. 1996, 133:617-630.
15. Ng J., Nardine T., Harms M., Tzu J., Goldstein A., Sun Y. Rac GTPases control axon growth guidance and branching. Nature 2002, 416:442-447.
16. Nolan K., Barrett K., Lu Y., Hu K.-Q., Vincent S., Settleman J. Myoblast city, the Drosophila homolog of Dock180/Ced-5, is required in a Rac signaling patway utilized for multiple developmental processes. Genes Dev. 1998, 12:3337-3342.
17. Pirraglia C., Myat M.M. Genetic regulation of salivary gland development in drosophila melanogaster. Salivary Glands: Development, Adaptations and Disease 2010, 14:32-47. S. Karger.
18. Pirraglia C., Jattani R., Myat M.M. Rac GTPase in epithelial tube morphogenesis. Dev. Biol. 2006, 290:435-446.
19. Pirraglia C., Walters J., Myat M.M. Pak1 control of E-cadherin endocytosis regulates salivary gland lumen size and shape. Development 2010, 137:4177-4189.
20. Reuter R., Panganiban G.E.F., Hoffman F.M., Scott M.P. Homeotic genes regulate the spatial expression of putative growth factors in the visceral mesoderm of Drosophila embryos. Development 1990, 110:1031-1040.
21. Rorth P. Collective cell migration. Annu. Rev. Cell Dev. Biol. 2009, 25:407-429.
22. Shaye D., Casanova J., Llimargas M. Modulation of intracellular trafficking regulates cell intercalation in the Drosophila trachea. Nat. Cell Biol. 2008, 10:964-970.
23. Stark K., Yee G., Roote C., Willimans E., Zusman S., Hynes R. A novel α integrin subunit associates with βPS and functions in tissue morphogenesis and movement during Drosophila development. Development 1997, 124:4583-4594.
24. Urbano J., Dominguez-Gimenez P., Estrada B., Martin-Bermudo M. PS integrins and laminins: key regulators of cell migration during Drosophila embryogenesis. PLoS One 2011, 6:e23893.
25. Vanderploeg J., Vazquez P., MacMullin A., Jacobs J. Integrins are required for cardioblast polarisation in Drosophila. BMC Dev. Biol. 2012, 12:8.
26. Vining M.S., Bradley P.L., Comeaux C.A., Andrew D.J. Organ positioning in Drosophila requires complex tissue-tissue interactions. Dev. Biol. 2005, 287:19-34.
27. Wang X., He L., Wu Y., Hahn K., Montell D. Light-mediated activation reveals a key role for Rac in collective guidance of cell migration in vivo. Nat. Cell Biol. 2010, 12:591-597.
28. Xu N., Keung B., Myat M. Rho GTPase controls invagination and cohesive migration of the Drosophila salivary gland through Crumbs and Rho-kinase. Dev. Biol. 2008, 321:88-100.
29. Xu N., Bagumian G., Galiano M., Myat M.M. Rho GTPase controls Drosophila salivary gland lumen size through regulation of the actin cytoskeleton and Moesin. Development 2011, 138:5415-5427.