Prolonged QT interval diagnosis suppression by a widely used computerized ECG analysis system

Circulation: Arrhythmia and Electrophysiology

Volumn 6, Issue 1, 2013, Pages 76-83

  Garg, Anubhav ^a   Lehmann, Michael H ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Computers; Electrocardiography; Long QT syndrome; Syncope; Torsade de pointes

Indexed keywords

ADULT; ALGORITHM; ARTICLE; CARDIOVASCULAR RISK; ELECTROCARDIOGRAM; FEMALE; HEART ARRHYTHMIA; HEART RATE; HUMAN; MALE; PRIORITY JOURNAL; QRS COMPLEX; QT INTERVAL; QT PROLONGATION; SINUS RHYTHM; WAVEFORM; AGED; AUTOMATION; DIAGNOSTIC ERROR; ELECTROCARDIOGRAPHY; HEART MUSCLE CONDUCTION SYSTEM; LONG QT SYNDROME; MIDDLE AGED; PATHOPHYSIOLOGY; PRACTICE GUIDELINE; PREDICTIVE VALUE; SIGNAL PROCESSING; STANDARD; TIME; UNITED STATES;

ADULT; AGED; AGED, 80 AND OVER; ALGORITHMS; AUTOMATION; DIAGNOSTIC ERRORS; ELECTROCARDIOGRAPHY; FEMALE; HEART CONDUCTION SYSTEM; HEART RATE; HUMANS; LONG QT SYNDROME; MALE; MICHIGAN; MIDDLE AGED; PRACTICE GUIDELINES AS TOPIC; PREDICTIVE VALUE OF TESTS; SIGNAL PROCESSING, COMPUTER-ASSISTED; TIME FACTORS;

MLCS; MLOWN;

EID: 84876307124     PISSN: 19413149     EISSN: 19413084     Source Type: Journal    
DOI: 10.1161/CIRCEP.112.976803     Document Type: Article

References (49)

1. Hongo RH, Goldschlager N. Status of computerized electrocardiography. Cardiol Clin. 2006;24:491-504, x.
2. Levine E, Rosero SZ, Budzikowski AS, Moss AJ, Zareba W, Daubert JP. Congenital long QT syndrome: considerations for primary care physicians. Cleve Clin J Med. 2008;75:591-600.
3. Cooper PN, Westby M, Pitcher DW, Bullock I. Synopsis of the National Institute for Health and Clinical Excellence Guideline for management of transient loss of consciousness. Ann Intern Med. 2011;155:543-549.
4. Johnson JN, Ackerman MJ. QTc: how long is too long? Br J Sports Med. 2009;43:657-662.
5. Roden DM. Drug-induced prolongation of the QT interval. N Engl J Med. 2004;350:1013-1022.
6. Drew BJ, Ackerman MJ, Funk M, Gibler WB, Kligfield P, Menon V, Philippides GJ, Roden DM, Zareba W; American Heart Association Acute Cardiac Care Committee of the Council on Clinical Cardiology; Council on Cardiovascular Nursing; American College of Cardiology Foundation. Prevention of torsade de pointes in hospital settings: a scientific statement from the American Heart Association and the American College of Cardiology Foundation. Circulation. 2010;121:1047-1060.
7. Elming H, Brendorp B, Køber L, Sahebzadah N, Torp-Petersen C. QTc interval in the assessment of cardiac risk. Card Electrophysiol Rev. 2002;6:289-294.
8. Viskin S, Rosovski U, Sands AJ, Chen E, Kistler PM, Kalman JM, Rodriguez Chavez L, Iturralde Torres P, Cruz F FE, Centurión OA, Fujiki A, Maury P, Chen X, Krahn AD, Roithinger F, Zhang L, Vincent GM, Zeltser D. Inaccurate electrocardiographic interpretation of long QT: the majority of physicians cannot recognize a long QT when they see one. Heart Rhythm. 2005;2:569-574.
9. Al-Khatib SM, Allen LaPointe NM, Kramer JM, Chen AY, Hammill BG, Delong L, Califf RM. A survey of health care practitioners' knowledge of the QT interval. J Gen Intern Med. 2005;20:392-396.
10. Hnatkova K, Gang Y, Batchvarov VN, Malik M. Precision of QT interval measurement by advanced electrocardiographic equipment. Pacing Clin Electrophysiol. 2006;29:1277-1284.
11. Miller MD, Porter CJ, Ackerman MJ. Diagnostic accuracy of screening electrocardiograms in long QT syndrome I. Pediatrics. 2001;108:8-12.
12. Marquette™ 12SL™ ECG Analysis Program: Physician's Guide, Revision E. Waukesha, WI: GE Healthcare; 2008: 6-73.
13. Bazett HC. An analysis of the time relations of electrocardiograms. Heart. 1920;7:353-370.
14. Rautaharju PM, Zhang ZM. Linearly scaled, rate-invariant normal limits for QT interval: eight decades of incorrect application of power functions. J Cardiovasc Electrophysiol. 2002;13:1211-1218.
15. Luo S, Michler K, Johnston P, Macfarlane PW. A comparison of commonly used QT correction formulae: the effect of heart rate on the QTc of normal ECGs. J Electrocardiol. 2004;37(suppl):81-90.
16. Rautaharju PM, Surawicz B, Gettes LS, Bailey JJ, Childers R, Deal BJ, Gorgels A, Hancock EW, Josephson M, Kligfield P, Kors JA, Macfarlane P, Mason JW, Mirvis DM, Okin P, Pahlm O, van Herpen G, Wagner GS, Wellens H; American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; American College of Cardiology Foundation; Heart Rhythm Society. AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part IV: the ST segment, T and U waves, and the QT interval: a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society. Endorsed by the International Society for Computerized Electrocardiology. J Am Coll Cardiol. 2009;53:982-991.
17. Grauer K, Kravitz L, Ariet M, Curry RW Jr, Nelson WP, Marriott HJ. Potential benefits of a computer ECG interpretation system for primary care physicians in a community hospital. J Am Board Fam Pract. 1989;2:17-24.
18. Kudenchuk PJ, Ho MT, Weaver WD, Litwin PE, Martin JS, Eisenberg MS, Hallstrom AP, Cobb LA, Kennedy JW. Accuracy of computer-interpreted electrocardiography in selecting patients for thrombolytic therapy. MITI Project Investigators. J Am Coll Cardiol. 1991;17:1486-1491.
19. Willems JL, Abreu-Lima C, Arnaud P, van Bemmel JH, Brohet C, Degani R, Denis B, Gehring J, Graham I, van Herpen G. The diagnostic performance of computer programs for the interpretation of electrocardiograms. N Engl J Med. 1991;325:1767-1773.
20. Farrell R, Xue J, Young B. Enhanced rhythm analysis for resting ECG using spectral and time-domain techniques. Comput Cardiol. 2003:733-736.
21. Poon K, Okin PM, Kligfield P. Diagnostic performance of a computerbased ECG rhythm algorithm. J Electrocardiol. 2005;38:235-238.
22. Goddard K, Roudsari A, Wyatt JC. Automation bias: a systematic review of frequency, effect mediators, and mitigators. J Am Med Inform Assoc. 2012;19:121-127.
23. Hillson SD, Connelly DP, Liu Y. The effects of computer-assisted electrocardiographic interpretation on physicians' diagnostic decisions. Med Decis Making. 1995;15:107-112.
24. Tsai TL, Fridsma DB, Gatti G. Computer decision support as a source of interpretation error: the case of electrocardiograms. J Am Med Inform Assoc. 2003;10:478-483.
25. Bogun F, Anh D, Kalahasty G, Wissner E, Bou Serhal C, Bazzi R, Weaver WD, Schuger C. Misdiagnosis of atrial fibrillation and its clinical consequences. Am J Med. 2004;117:636-642.
26. Anh D, Krishnan S, Bogun F. Accuracy of electrocardiogram interpretation by cardiologists in the setting of incorrect computer analysis. J Electrocardiol. 2006;39:343-345.
27. Southern WN, Arnsten JH. The effect of erroneous computer interpretation of ECGs on resident decision making. Med Decis Making. 2009;29:372-376.
28. Goldenberg I, Moss AJ, Zareba W. QT interval: how to measure it and what is "normal". J Cardiovasc Electrophysiol. 2006;17:333-336.
29. Moss AJ, Zareba W, Benhorin J, Locati EH, Hall WJ, Robinson JL, Schwartz PJ, Towbin JA, Vincent GM, Lehmann MH. ECG T-wave patterns in genetically distinct forms of the hereditary long QT syndrome. Circulation. 1995;92:2929-2934.
30. Zhang L, Timothy KW, Vincent GM, Lehmann MH, Fox J, Giuli LC, Shen J, Splawski I, Priori SG, Compton SJ, Yanowitz F, Benhorin J, Moss AJ, Schwartz PJ, Robinson JL, Wang Q, Zareba W, Keating MT, Towbin JA, Napolitano C, Medina A. Spectrum of ST-T-wave patterns and repolarization parameters in congenital long-QT syndrome: ECG findings identify genotypes. Circulation. 2000;102:2849-2855.
31. Halkin A, Roth A, Lurie I, Fish R, Belhassen B, Viskin S. Pausedependent torsade de pointes following acute myocardial infarction: a variant of the acquired long QT syndrome. J Am Coll Cardiol. 2001;38: 1168-1174.
32. Kawabata M, Hirao K, Takeshi S, Sakurai K, Inagaki H, Hachiya H, Isobe M. Torsades de pointes related to transient marked QT prolongation following successful emergent percutaneous coronary intervention for acute coronary syndrome. J Electrocardiol. 2008;41:117-122.
33. Samuelov-Kinori L, Kinori M, Kogan Y, Swartzon M, Shalev H, Guy D, Ferenidou F, Mashav N, Sadeh B, Atzmony L, Kliuk-Ben-Basat O, Steinvil A, Justo D. Takotsubo cardiomyopathy and QT interval prolongation: who are the patients at risk for torsades de pointes? J Electrocardiol. 2009;42:353-357.e1.
34. Behr ER, Saagar M. Takotsubo cardiomyopathy and the long-QT syndrome: an insult to repolarization reserve. Europace. 2009;11:697-700.
35. Madias C, Fitzgibbons TP, Alsheikh-Ali AA, Bouchard JL, Kalsmith B, Garlitski AC, Tighe DA, Estes NAM, Aurigemma GP, Link MS. Acquired long QT syndrome from stress cardiomyopathy is associated with ventricular arrhythmias and torsades de pointes. Heart Rhythm. 2011;8:555-561.
36. Crotti L, Hu D, Barajas-Martinez H, De Ferrari GM, Oliva A, Insolia R, Pollevick GD, Dagradi F, Guerchicoff A, Greco F, Schwartz PJ, Viskin S, Antzelevitch C. Torsade de pointes following acute myocardial infarction: evidence for a deadly link with a common genetic variant. Heart Rhythm. 2012;9:1104-1112.
37. Betapace AF [package insert]. Wayne, NJ: Bayer HealthCare Pharmaceuticals; 2011.
38. Tikosyn [package insert]. New York, NY: Pfizer Labs; 2011.
39. Thioridazine Hydrochloride [package insert]. Morgantown, WV: Mylan Pharmaceuticals; 2010.
40. Priori SG, Schwartz PJ, Napolitano C, Bloise R, Ronchetti E, Grillo M, Vicentini A, Spazzolini C, Nastoli J, Bottelli G, Folli R, Cappelletti D. Risk stratification in the long-QT syndrome. N Engl J Med. 2003; 348:1866-1874.
41. Sauer AJ, Moss AJ, McNitt S, Peterson DR, Zareba W, Robinson JL, Qi M, Goldenberg I, Hobbs JB, Ackerman MJ, Benhorin J, Hall WJ, Kaufman ES, Locati EH, Napolitano C, Priori SG, Schwartz PJ, Towbin JA, Vincent GM, Zhang L. Long QT syndrome in adults. J Am Coll Cardiol. 2007;49:329-337.
42. Liu JF, Jons C, Moss AJ, McNitt S, Peterson DR, Qi M, Zareba W, Robinson JL, Barsheshet A, Ackerman MJ, Benhorin J, Kaufman ES, Locati EH, Napolitano C, Priori SG, Schwartz PJ, Towbin J, Vincent M, Zhang L, Goldenberg I; International Long QT Syndrome Registry. Risk Factors for Recurrent Syncope and Subsequent Fatal or Near-Fatal Events in Children and Adolescents With Long QT Syndrome. J Am Coll Cardiol. 2011;57:941-950.
43. Marquette™ 12SL™ ECG Analysis Program: Physician's Guide, Revision E. Waukesha, WI: GE Healthcare; 2008: 6-25.
44. Kligfield P, Tyl B, Maarek M, Maison-Blanche P. Magnitude, mechanism, and reproducibility of QT interval differences between superimposed global and individual lead ECG complexes. Ann Noninvasive Electrocardiol. 2007;12:145-152.
45. Mason JW, Ramseth DJ, Chanter DO, Moon TE, Goodman DB, Mendzelevski B. Electrocardiographic reference ranges derived from 79,743 ambulatory subjects. J Electrocardiol. 2007;40:228-234.
46. Taggart NW, Haglund CM, Tester DJ, Ackerman MJ. Diagnostic miscues in congenital long-QT syndrome. Circulation. 2007;115:2613-2620.
47. Marquette™ 12SL™ ECG Analysis Program: Physician's Guide, Revision A. Waukesha, WI: GE Healthcare; 2010: 6-71.
48. Marquette™ 12SL™ ECG Analysis Program: Physician's Guide, Revision A. Waukesha, WI: GE Healthcare; 2010: 10-3 and 10-16.
49. Uberoi A, Stein R, Perez MV, Freeman J, Wheeler M, Dewey F, Peidro R, Hadley D, Drezner J, Sharma S, Pelliccia A, Corrado D, Niebauer J, Estes NA 3rd, Ashley E, Froelicher V. Interpretation of the electrocardiogram of young athletes. Circulation. 2011;124:746-757.