Donor diabetes mellitus is an independent risk factor for graft loss in HCV positive but not HCV negative liver transplant recipients

Digestive Diseases and Sciences

Volumn 58, Issue 2, 2013, Pages 574-578

  Wu, Ying ^a   Ahmed, Aijaz ^b   Kamal, Ahmad ^b,c  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b STANFORD UNIVERSITY   (United States)

^c SANTA CLARA VALLEY MEDICAL CENTER   (United States)

Author keywords

Diabetes mellitus type II; Hepatitis C; Liver donor; Liver transplantation

Indexed keywords

ADULT; ARTICLE; CARDIOVASCULAR RISK; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; GRAFT FAILURE; GRAFT RECIPIENT; GRAFT SURVIVAL; HUMAN; LIVER GRAFT; MALE; ORGAN DONOR; PRIORITY JOURNAL; RISK FACTOR; COHORT ANALYSIS; COMPARATIVE STUDY; DONOR; FACTUAL DATABASE; HEPATITIS C; KAPLAN MEIER METHOD; LIVER TRANSPLANTATION; MIDDLE AGED; MORTALITY; NON INSULIN DEPENDENT DIABETES MELLITUS; PREVALENCE; PRIMARY GRAFT DYSFUNCTION; PROPORTIONAL HAZARDS MODEL; STATISTICS; UNITED STATES;

ADULT; COHORT STUDIES; DATABASES, FACTUAL; DIABETES MELLITUS, TYPE 2; FEMALE; GRAFT SURVIVAL; HEPATITIS C, CHRONIC; HUMANS; KAPLAN-MEIER ESTIMATE; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; PREVALENCE; PRIMARY GRAFT DYSFUNCTION; PROPORTIONAL HAZARDS MODELS; RISK FACTORS; TISSUE DONORS; UNITED STATES;

MLCS; MLOWN;

EID: 84876302379     PISSN: 01632116     EISSN: 15732568     Source Type: Journal    
DOI: 10.1007/s10620-012-2345-7     Document Type: Article

References (11)

1. Verna EC, Brown RS Jr. Hepatitis C virus and liver transplantation. Clin Liver Dis. 2006;10(4):919.
2. Berenguer M. Risk of extended criteria donors in hepatitis C virus positive recipients. Liver Transpl. 2008;14:S45-S50.
3. Forman LM, Lewis JD, Berlin JA, et al. The association between hepatitis C infection and survival after orthotopic liver transplantation. Gastroenterology. 2002;122:889.
4. Feng S, Goodrich NP, Bragg-Gresham JL, et al. Characteristics associated with liver graft failure: the concept of a donor risk index. Am J Transplant. 2006;6:783-790.
5. Kotronen A, Juurinen L, Tiikkainen M, Vehkavaara S, Yki-järvinen H. Increased liver fat, impaired insulin clearance, and hepatic and adipose tissue insulin resistance in Type 2 diabetes. Gastroenterology. 2008;135:122-130.
6. Angulo P, Keach JC, Batts KP, Lindor KD. Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis. Hepatology. 1999;306:1356-1362.
7. Mulhall BP, Ong JP, Younossi ZM. Non-alcoholic fatty liver disease: an overview. J Gastroenterol Hepatol. 2002;17:1136-1143.
8. Evan JL, Goldfine ID, Maddux BA, Grudsky GM. Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr Rev. 2002;23:599-622.
9. Prolisso G, D'Amore A, Volpe C, et al. Evidence for a relationship between oxidative stress and insulin action in noninsulin dependent [type II] diabetic patients. Metabolism. 1994;43:1426-1429.
10. Nocito A, El-Bardy AM, Clavien PA. When is steatosis too much for transplantation? J Hepatol. 2006;45:494-499.
11. Briceno J, Ciria R, Pleguezuelo M, et al. Contribution of marginal donors to liver transplantation for hepatitis C virus infection. Transpl Proc. 2007;39:2297-2299.