Essential fatty acids deficiency promotes lipogenic gene expression and hepatic steatosis through the liver X receptor

Journal of Hepatology

Volumn 58, Issue 5, 2013, Pages 984-992

  Ducheix, Simon ^a   Montagner, Alexandra ^a   Polizzi, Arnaud ^a   Lasserre, Frédéric ^a   Marmugi, Alice ^a   Bertrand Michel, Justine ^b   Podechard, Normand ^c   Al Saati, Talal ^d   Chétiveaux, Maud ^e   Baron, Silvère ^e,f,g   Boué, Jérôme ^e   Dietrich, Gilles ^e   Mselli Lakhal, Laila ^a   Costet, Philippe ^e   Lobaccaro, Jean Marc A ^e,f,g   Pineau, Thierry ^a   Theodorou, Vassilia ^a   Postic, Catherine ^e,h,i   Martin, Pascal G P ^a   Guillou, Hervé ^a  

^a TOXALIM RESEARCH CENTRE IN FOOD TOXICOLOGY   (France)

^b INSERM   (France)

^c UNIVERSITÉ DE RENNES 1   (France)

^d CHU PURPAN   (France)

^e L INSTITUT DU THORAX   (France)

^f UNIVERSITÉ CLERMONT AUVERGNE   (France)

^g CRNH AUVERGNE   (France)

^h INSTITUT COCHIN   (France)

ⁱ UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Cholesterol; Lipogenesis; LXR; Polyunsaturated fatty acids; Steatosis

Indexed keywords

CHOLESTEROL; ESSENTIAL FATTY ACID; LIVER X RECEPTOR; TRANSCRIPTION FACTOR; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ESSENTIAL FATTY ACID DEFICIENCY; FATTY LIVER; FEMALE; GENE EXPRESSION REGULATION; GENOTYPE; LIPOGENESIS; MALE; MOUSE; NONHUMAN; NUTRIGENOMICS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS;

ANIMALS; CHOLESTEROL; DEFICIENCY DISEASES; DIETARY FATS; DISEASE MODELS, ANIMAL; FATTY ACIDS, ESSENTIAL; FATTY LIVER; FEMALE; GENE EXPRESSION; LIPOGENESIS; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; ORPHAN NUCLEAR RECEPTORS; TRANSCRIPTION FACTORS; TRIGLYCERIDES; UP-REGULATION;

EID: 84876286365     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2013.01.006     Document Type: Article

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