-
1
-
-
54049114754
-
Clinical and histological aspects of cnv formation: Studies in an animal model
-
Thesis 2
-
Lassota N. Clinical and histological aspects of CNV formation: studies in an animal model. Acta Ophthalmol 2008; 86 (Thesis 2):1-24.
-
(2008)
Acta Ophthalmol
, vol.86
, pp. 1-24
-
-
Lassota, N.1
-
2
-
-
0033694993
-
Mechanisms of action of photodynamic therapy with verteporfin for the treatment of age-related macular degeneration
-
Schmidt-Erfurth U, Hasan T. Mechanisms of action of photodynamic therapy with verteporfin for the treatment of age-related macular degeneration. Surv Ophthalmol 2000; 45:195-214.
-
(2000)
Surv Ophthalmol
, vol.45
, pp. 195-214
-
-
Schmidt-Erfurth, U.1
Hasan, T.2
-
3
-
-
13444273215
-
Photodynamic therapy with verteporfin combined with intravitreal injection of triamcinolone acetonide for choroidal neovascularization
-
Spaide RF, Sorenson J, Maranan L. Photodynamic therapy with verteporfin combined with intravitreal injection of triamcinolone acetonide for choroidal neovascularization. Ophthalmology 2005; 112:301-304.
-
(2005)
Ophthalmology
, vol.112
, pp. 301-304
-
-
Spaide, R.F.1
Sorenson, J.2
Maranan, L.3
-
4
-
-
10744228532
-
Polypoidal choroidal vasculopathy: Incidence, demographic features, and clinical characteristics
-
Sho K, Takahashi K, Yamada H, et al. Polypoidal choroidal vasculopathy: incidence, demographic features, and clinical characteristics. Arch Ophthalmol 2003; 121:1392-1396.
-
(2003)
Arch Ophthalmol
, vol.121
, pp. 1392-1396
-
-
Sho, K.1
Takahashi, K.2
Yamada, H.3
-
5
-
-
0036319078
-
Polypoidal choroidal vasculopathy in chinese patients
-
Kwok AKH, Lai TYY, Chan CWN, et al. Polypoidal choroidal vasculopathy in Chinese patients. Br J Ophthalmol 2002; 86:892-897.
-
(2002)
Br J Ophthalmol
, vol.86
, pp. 892-897
-
-
Kwok, A.K.H.1
Lai, T.Y.Y.2
Chan, C.W.N.3
-
6
-
-
33746669920
-
Polypoidal choroidal vasculopathy and retinochoroidal anastomosis in japanese patients eligible for photodynamic therapy for exudative age-related macular degeneration
-
Obata R, Yanagi Y, Kami J, et al. Polypoidal choroidal vasculopathy and retinochoroidal anastomosis in Japanese patients eligible for photodynamic therapy for exudative age-related macular degeneration. Jpn J Ophthalmol 2006; 50:354-360.
-
(2006)
Jpn J Ophthalmol
, vol.50
, pp. 354-360
-
-
Obata, R.1
Yanagi, Y.2
Kami, J.3
-
7
-
-
48249145146
-
Prevalence and associated risk factors of age-related macular degeneration in an elderly chinese population in taiwan: The shihpai eye study
-
Chen SJ, Cheng CY, Peng KL, et al. Prevalence and associated risk factors of age-related macular degeneration in an Elderly Chinese Population in Taiwan: The Shihpai Eye Study. Invest Ophthalmol Vis Sci 2008; 49:3126-3133.
-
(2008)
Invest Ophthalmol Vis Sci
, vol.49
, pp. 3126-3133
-
-
Chen, S.J.1
Cheng, C.Y.2
Peng, K.L.3
-
8
-
-
84865721295
-
Everest study: Efficacy and safety of verteporfin photodynamic therapy in combination with ranibizumab or alone versus ranibizumab monotherapy in patients with symptomatic macular polypoidal choroidal vasculopathy
-
The EVEREST trial reported that verteporfin PDT combined with ranibizumab 0.5mg or alone was superior to ranibizumab monotherapy in achieving complete regression of polyps in this 6-month study in patients with symptomatic macular polypoidal choroidal vasculopathy
-
Koh A, Lee WK, Chen LJ, et al. EVEREST study: efficacy and safety of verteporfin photodynamic therapy in combination with ranibizumab or alone versus ranibizumab monotherapy in Patients with symptomatic macular polypoidal choroidal vasculopathy. Retina 2012; 32:1453-1464. The EVEREST trial reported that verteporfin PDT combined with ranibizumab 0.5mg or alone was superior to ranibizumab monotherapy in achieving complete regression of polyps in this 6-month study in patients with symptomatic macular polypoidal choroidal vasculopathy.
-
(2012)
Retina
, vol.32
, pp. 1453-1464
-
-
Koh, A.1
Lee, W.K.2
Chen, L.J.3
-
9
-
-
84860450956
-
Verteporfin plus ranibizumab for choroidal neovascularization in age-related macular degeneration
-
The DENALI trial investigated whether verteporfin standard or reduced fluence in combination with ranibizumab administered with a loading phase followed by PRN was noninferior to fixed monthly ranibizumab injections. Noninferiority of either combination regimen to monthly ranibizumab injections was not demonstrated; however, both combination regimens resulted in BCVA gains at month 12
-
Kaiser PK, Boyer DS, Cruess AF, et al. Verteporfin plus ranibizumab for choroidal neovascularization in age-related macular degeneration. Ophthalmology 2012; 119:1001-1010. The DENALI trial investigated whether verteporfin standard or reduced fluence in combination with ranibizumab administered with a loading phase followed by PRN was noninferior to fixed monthly ranibizumab injections. Noninferiority of either combination regimen to monthly ranibizumab injections was not demonstrated; however, both combination regimens resulted in BCVA gains at month 12.
-
(2012)
Ophthalmology
, vol.119
, pp. 1001-1010
-
-
Kaiser, P.K.1
Boyer, D.S.2
Cruess, A.F.3
-
10
-
-
66149117478
-
Intravitreal ranibizumab, intravitreal ranibizumab with pdt, and intravitreal triamcinolone with pdt for the treatment of retinal angiomatous proliferation: A prospective study
-
Rouvas AA, Papakostas TD, Vavvas D, et al. Intravitreal ranibizumab, intravitreal ranibizumab with PDT, and intravitreal triamcinolone with PDT for the treatment of retinal angiomatous proliferation: a prospective study. Retina 2009; 29:536-544.
-
(2009)
Retina
, vol.29
, pp. 536-544
-
-
Rouvas, A.A.1
Papakostas, T.D.2
Vavvas, D.3
-
11
-
-
84876297898
-
-
Full Text View -ClinicalTrials.gov. clinicaltrialsgov. Accessed 2 November 2012]. The RADICAL study result showed that triple combination therapy significantly decreased the number of retreatment visits required over 2 years. Of the four treatment groups, the triple therapy half-fluence group had the fewest retreatment visits compared with ranibizumab monotherapy
-
Reduced Fluence Visudyne-Anti-VEGF-Dexamethasone In Combination for AMD Lesions (RADICAL). Full Text View -ClinicalTrials.gov. clinicaltrialsgov. http://clinicaltrials.gov/ct2/show/study/NCT00492284. [Accessed 2 November 2012]. The RADICAL study result showed that triple combination therapy significantly decreased the number of retreatment visits required over 2 years. Of the four treatment groups, the triple therapy half-fluence group had the fewest retreatment visits compared with ranibizumab monotherapy.
-
Reduced Fluence Visudyne-Anti-VEGF-Dexamethasone In Combination for AMD Lesions (RADICAL)
-
-
-
12
-
-
0034026061
-
External beam radiotherapy in exudative agerelated macular degeneration: A pooled analysis of phase i data
-
Chakravarthy U, MacKenzie G. External beam radiotherapy in exudative agerelated macular degeneration: a pooled analysis of phase I data. Br J Radiol 2000; 73:305-313.
-
(2000)
Br J Radiol
, vol.73
, pp. 305-313
-
-
Chakravarthy, U.1
MacKenzie, G.2
-
13
-
-
16244387671
-
Strontium plaque brachytherapy for exudative age-related macular degeneration. Three-year results of a randomized study
-
Jaakkola A, Heikkonen J, Tommila P, et al. Strontium plaque brachytherapy for exudative age-related macular degeneration. Three-year results of a randomized study. Ophthalmology 2005; 112:567e1-573e1.
-
(2005)
Ophthalmology
, vol.112
-
-
Jaakkola, A.1
Heikkonen, J.2
Tommila, P.3
-
15
-
-
84855206213
-
Three-year safety and vision results of epimacular 90strontium/90yttrium brachytherapy with bevacizumab for the treatment of subfoveal choroidal neovascularization secondary to age-related macular degeneration
-
This study revived interest in radiation therapy combined with anti-VEGF agents because of the outstanding results. These results were not replicated in larger phase 3 studies
-
Ávila MP, Farah ME, Santos A, et al. Three-year safety and vision results of epimacular 90Strontium/90Yttrium brachytherapy with bevacizumab for the treatment of subfoveal choroidal neovascularization secondary to age-related macular degeneration. Retina 2012; 32:10-18. This study revived interest in radiation therapy combined with anti-VEGF agents because of the outstanding results. These results were not replicated in larger phase 3 studies.
-
(2012)
Retina
, vol.32
, pp. 10-18
-
-
Ávila, M.P.1
Farah, M.E.2
Santos, A.3
-
16
-
-
38349172455
-
Randomized, double-masked, shamcontrolled trial of ranibizumab for neovascular age-related macular degeneration: Pier study year 1
-
Regillo CD, Brown DM, Abraham P, et al. Randomized, double-masked, shamcontrolled trial of ranibizumab for neovascular age-related macular degeneration: PIER Study year 1. Am J Ophthalmol 2008; 145:239-248.
-
(2008)
Am J Ophthalmol
, vol.145
, pp. 239-248
-
-
Regillo, C.D.1
Brown, D.M.2
Abraham, P.3
-
17
-
-
84856084701
-
24-Gy low-voltage X-ray irradiation with ranibizumab therapy for neovascular AMD: 6-month safety and functional outcomes
-
Canton VM, Quiroz-Mercado H, Velez-Montoya R, et al. 24-Gy low-voltage X-ray irradiation with ranibizumab therapy for neovascular AMD: 6-month safety and functional outcomes. Ophthalmic Surg Lasers Imaging 2012; 43:20-24.
-
(2012)
Ophthalmic Surg Lasers Imaging
, vol.43
, pp. 20-24
-
-
Canton, V.M.1
Quiroz-Mercado, H.2
Velez-Montoya, R.3
-
18
-
-
84867090012
-
16 Gy lowvoltage x-ray irradiation followed by as needed ranibizumab therapy for age-related macular degeneration: 12 month outcomes of a 'radiation-first' strategy
-
Moshfeghi AA, Morales-Canton V, Quiroz-Mercado H, et al. 16 Gy lowvoltage X-ray irradiation followed by as needed ranibizumab therapy for age-related macular degeneration: 12 month outcomes of a 'radiation-first' strategy. Br J Ophthalmol 2012; 96:1320-1324.
-
(2012)
Br J Ophthalmol
, vol.96
, pp. 1320-1324
-
-
Moshfeghi, A.A.1
Morales-Canton, V.2
Quiroz-Mercado, H.3
-
19
-
-
84876287895
-
-
Full Text View -ClinicalTrials.gov.clinicaltrialsgov. [Accessed 2 October 2012]
-
INTREPID -IRay Plus Anti-VEGF Treatment For Patients With Wet AMD. Full Text View -ClinicalTrials.gov. clinicaltrialsgov. http://clinicaltrials.gov/ct2/ show/NCT01016873?termoraya&rank2. [Accessed 2 October 2012].
-
INTREPID-IRay Plus Anti-VEGF Treatment For Patients With Wet AMD
-
-
-
20
-
-
84876291723
-
-
www.orayainc.com/wp-content/uploads/2012/05/Oraya-INTREPID-Press-Release. pdf. orayainc.com.
-
-
-
-
21
-
-
84876291261
-
-
[Accessed 2 October 2012]. The INTREPID clinical trial of radiation therapy met its primary endpoint of reduction in anti-VEGF injections for patients with wet AMD. The INTREPID study is the first, sham-controlled, double-masked trial to evaluate the effectiveness and safety of a one-timeradiation therapy in conjunction with as-needed anti-VEGF injections for the treatment of wet AMD
-
http://www.orayainc.com/wp-content/uploads/2012/05/Oraya-INTREPID-Press- Release.pdf. [Accessed 2 October 2012]. The INTREPID clinical trial of radiation therapy met its primary endpoint of reduction in anti-VEGF injections for patients with wet AMD. The INTREPID study is the first, sham-controlled, double-masked trial to evaluate the effectiveness and safety of a one-timeradiation therapy in conjunction with as-needed anti-VEGF injections for the treatment of wet AMD.
-
-
-
-
22
-
-
38549170371
-
Intravitreal bevacizumab and triamcinolone acetonide combination therapy for exudative neovascular age-related macular degeneration: Shortterm optical coherence tomography results
-
Colucciello M. Intravitreal bevacizumab and triamcinolone acetonide combination therapy for exudative neovascular age-related macular degeneration: shortterm optical coherence tomography results. J Ocul Pharmacol Ther 2008; 24:15-24.
-
(2008)
J Ocul Pharmacol Ther
, vol.24
, pp. 15-24
-
-
Colucciello, M.1
-
23
-
-
77956214077
-
Combined intravitreal bevacizumab and triamcinolone in exudative age-related macular degeneration
-
Jonas JB, Libondi T, Golubkina L, et al. Combined intravitreal bevacizumab and triamcinolone in exudative age-related macular degeneration. Acta Ophthalmol 2009; 88:630-634.
-
(2009)
Acta Ophthalmol
, vol.88
, pp. 630-634
-
-
Jonas, J.B.1
Libondi, T.2
Golubkina, L.3
-
24
-
-
58549115679
-
Effects of pdgf-c and pdgf-d on monocyte migration and mmp-2 and mmp-9 expression
-
Wa°gsater D, Zhu C, Bjorck HM, Eriksson P. Effects of PDGF-C and PDGF-D on monocyte migration and MMP-2 and MMP-9 expression. Atherosclerosis 2009; 202:415-423.
-
(2009)
Atherosclerosis
, vol.202
, pp. 415-423
-
-
Wagsater, D.1
Zhu, C.2
Bjorck, H.M.3
Eriksson, P.4
-
25
-
-
77955435616
-
Pdgf-cc blockade inhibits pathological angiogenesis by acting on multiple cellular and molecular targets
-
Hou X, Kumar A, Lee C, et al. PDGF-CC blockade inhibits pathological angiogenesis by acting on multiple cellular and molecular targets. Proc Natl Acad Sci USA 2010; 107:12216-12221.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 12216-12221
-
-
Hou, X.1
Kumar, A.2
Lee, C.3
|