Anti-diabetic activity of swertiamarin is due to an active metabolite, gentianine, that upregulates PPAR-γ gene expression in 3T3-L1 cells

Phytotherapy Research

Volumn 27, Issue 4, 2013, Pages 624-627

  Vaidya, Hitesh ^a,c   Goyal, Ramesh K ^b   Cheema, Sukhinder Kaur ^c  

^a L M COLLEGE OF PHARMACY   (India)

^b SVKM s Narsee Monjee Institute of Management Studies   (India)

^c MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

Author keywords

adiponectin; Diabetes; gentianine; GLUT 4; PPAR ; swertiamarin

Indexed keywords

ADIPONECTIN; DRUG METABOLITE; GENTIANINE; GLUCOSE TRANSPORTER 4; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PLANT GLYCOSIDE; SWERTIAMARIN; UNCLASSIFIED DRUG;

ADIPOGENESIS; ANIMAL CELL; ANTIDIABETIC ACTIVITY; ARTICLE; CELL DIFFERENTIATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE EXPRESSION; MOUSE; NONHUMAN; PROADIPOCYTE; UPREGULATION;

3T3-L1 CELLS; ADIPOGENESIS; ADIPONECTIN; ALKALOIDS; ANIMALS; CELL DIFFERENTIATION; GLUCOSE TRANSPORTER TYPE 4; HYPOGLYCEMIC AGENTS; IRIDOID GLUCOSIDES; MICE; PPAR GAMMA; PYRONES; UP-REGULATION;

EID: 84876281723     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.4763     Document Type: Article

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