Fatal neuroinflammation in a case of multiple sclerosis with anti-natalizumab antibodies

Neurology

Volumn 80, Issue 10, 2013, Pages 965-967

  Svenningsson, Anders ^a   Dring, Ann M ^a   Fogdell Hahn, Anna ^c   Jones, Iwan ^b   Engdahl, Elin ^c   Lundkvist, Malin ^c   Brännström, Thomas ^a   Gilthorpe, Jonathan D ^a  

^a UMEÅ UNIVERSITY   (Sweden)

^b UMEÅ UNIVERSITY   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; BETA1A INTERFERON; COMPLEMENT COMPONENT C9; DRUG ANTIBODY; GADOLINIUM; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; METHYLPREDNISOLONE; NATALIZUMAB; NATALIZUMAB ANTIBODY; UNCLASSIFIED DRUG;

ADULT; BRAIN BIOPSY; CASE REPORT; CEREBROSPINAL FLUID ANALYSIS; CLINICAL FEATURE; CONTRAST ENHANCEMENT; DISEASE EXACERBATION; EXPANDED DISABILITY STATUS SCALE; FEMALE; HUMAN; HUMAN TISSUE; MULTIPLE SCLEROSIS; NERVOUS SYSTEM INFLAMMATION; NOTE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL;

ADULT; ANTIBODIES; ANTIBODIES, MONOCLONAL, HUMANIZED; ENCEPHALITIS; FATAL OUTCOME; FEMALE; HUMANS; MULTIPLE SCLEROSIS;

EID: 84876251384     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0b013e3182840be3     Document Type: Note

References (4)

1. Berger JR. Paradoxically aggressive multiple sclerosis in the face of natalizumab therapy. Mult Scler 2008;14:708-710.
2. Miravalle A, Jensen R, Kinkel RP. Immune reconstitution inflammatory syndrome in patients with multiple sclerosis following cessation of natalizumab therapy. Arch Neurol 2011; 68:186-191.
3. Papeix C, Depaz R, Tourbah A, Stankoff B, Lubetzki C. Dramatic worsening following plasma exchange in severe post-natalizumab withdrawal multiple sclerosis relapse. Mult Scler 2011;17:1520-1522.
4. Lenhard T, Biller A, Mueller W, Metz I, Schonberger J, Wildemann B. Immune reconstitution inflammatory syndrome after withdrawal of natalizumab? Neurology 2010;75:831-833.