Polyesteramide Coatings for Drug Eluting Stents: Controlling Drug Release by Polymer Engineering

Studies in Mechanobiology, Tissue Engineering and Biomaterials

Volumn 8, Issue , 2011, Pages 127-143

  Trollsas, Mikael ^a   Maslanka, Bozena ^a   Pham, Nam ^a   Lin, Qing ^a   Hossainy, Syed ^a   Hsu, Shaw Ling ^b   Ngo, Michael Huy ^a  

^a ABBOTT VASCULAR   (United States)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

Control Drug Release; Drug Release; Drug Release Rate; Glass Transition Temperature; Molecular Mobility

Indexed keywords

EID: 84876235499     PISSN: 18682006     EISSN: 18682014     Source Type: Book Series    
DOI: 10.1007/8415_2010_57     Document Type: Chapter

References (34)

1. Venkatraman, S., Boey, F.: Release profiles in drug-eluting stents: Issues and uncertainties. J. Control. Release 120, 149–160 (2007)
2. Acharya, G., Park, K.: Mechanisms of controlled drug release from drug-eluting stent. Adv. Drug Deliv. Rev. 58, 387–401 (2006)
3. Burt, H.M., Hunter, W.L.: Drug-eluting stents: A multidisciplinary success story. Adv. Drug Deliv. Rev. 58, 350–357 (2006)
4. Commendeur, S., Van Beusekom, H.M.M., Van der Giessen, W.J.: Polymers, drug release, and drug-eluting stents. J. Interven. Cardiol. 19, 500–506 (2006)
5. Ellis, J.T., Kilpatrick, D.L., Consigny, P., Prabhu, S., Hossainy, S.F.A.: Therapy considerations in drug eluting stents. Crit. Rev. Ther. Drug Carr. Syst. 22, 1–25 (2004)
6. Lewis, A.L., Vick, T.A., Collias, A.C.M., Hughes, L.G., Palmer, R.R., Leppard, S.W., Furze, J.D., Taylor, A.S., Stratford, P.W.: Stratford ‘‘Phosphorylcholine-based polymer coatings for stent drug delivery. J. Mater. Sci.: Mater. Med. 12, 865–870 (2001)
7. Langer, R.: New methods of drug delivery. Science 249, 1527–1533 (1990)
8. Das, G.S., Rao, G.H.R., Wilson, R.F., Chandy, T.: Colchicine encapsulation within poly(ethyleneglycol)-coated poly(lactic acid)/poly(-caprolactone) microspheres-controlled release studies. Drug Deliv. 7, 129–138 (2000)
9. Pitt, C.G.: Poly (e-caprolactone) and its copolymers’’ in Biodegradable Polymers as Drug Delivery Systems. In: Langer, R., Chasin, M. (eds.) Biodegradable Polymers as Drug Delivery Systems, pp. 71–120. Marcel Dekker, New York, NY (1990)
10. Gref, R., Minamitae, Y., Peracchia, M.T., Trubetskoy, V., Torchillin, V., Langer, R.: Biodegradable long-circulating polymeric nanospheres. Science 263, 1600–1603 (1994)
11. Albertsson, A.C., Varma, I.K.: Recent developments in ring opening polymerization of lactones for biomedical applications. Biomacromolecules 4, 1466–1486 (2003)
12. Dechy-Cabaret, O., Martin-Vaca, B., Bourissou, D.: Controlled ring-opening polymerization of lactide and glycolide. Chem. Rev. 104, 6147–6176 (2004)
13. Mecerreyes, D., Moineau, G., Dubois, P., Jerome, R., Hedrick, J.L., Hawker, C.J., Malmström, E.E., Trollsås, M.: Simultaneous dual living polymerizations: a novel approach to block and graft copolymers. Angew. Chem. 37, 1274 (1998)
14. Hawker, C.J., Hedrick, J.L., Malmström, E.E., Trollsås, M., Mecerreyes, D., Moineau, G., Dubois, P., Jerome, R.: Dual living polymerizations from a double headed initiator. Macromolecules 31, 213 (1998)
15. Trollsås, M., Hedrick, J.L., Mecerreyes, D., Dubois, P., Jerome, R., Ihre, H., Hult, A.: Versatile and controlled synthesis of star and branched macromolecules by dendritic initiation. Macromolecules 30, 8508 (1997)
16. Trollsås, M., Hedrick, J.L.: Dendrimer-like star polymers. J. Am. Chem. Soc. 120, 4644 (1998)
17. Hedrick, J., Trollsas, M., Hawker, C., Atthoff, B., Claesson, H., Heise, A., Miller, R., Mecerreyes, D., Jerome, R., Dubois, P.: Dendrimer-like star and block amphiphilic copolymers by combination of ring-opening and atom transfer radical polymerization. Macromolecules 31, 8691 (1998)
18. Trollsås, M., Atthoff, B., Claesson, H., Hedrick, J.L.: Layered dendritic block copolymers. Angew. Chem. Int. Ed. Engl. 37, 3132 (1998)
19. Bates, F.S.: Polymer-polymer phase-behavior. Science 251, 898–905 (1991)
20. Fredrickson, G.H., Bates, F.S.: Block copolymers-Designer soft materials. Phys. Today 52, 32–38 (1999)
21. Katsarava, R., Beridze, V., Arabuli, N., Kharadze, D.: Amino acid-based bioanalogous polymers. Synthesis and study of regular poly(ester amide)s based on bis(a-amino acid), a-x-alkylene diesters, and aliphatic dicarboxylic acids. J. Polym. Sci. A: Polym. Chem. 37, 391–407 (1999)
22. Kharadze, D., Kirmelashvili, L., Medzmariashvili, N., Beridze, V., Tsitlanadze, G., Tugushi, D., Chu, C.C., Katsarava, R.: Synthesis and a-chymotrypsinolysis of regular poly(ester amides) based on phenylalanine, diols, and terephthalic acid. Polym. Sci. A 41, 883–890 (1999)
23. Arabuli, N., Tsitlanadze, G., Edilashvili, L., Kharadze, D., Goguadze, T., Beridze, V., Gomurashvili, Z., Katsarava, R.: Heterochain polymers based on natural amino-acids-synthesis and enzymatichydrolysis of regular poly(ester-amide)s based on bis(L-phenylalanine) a,w-alkylene diesters and adipic acid. Macromol. Chem. Phys. 195, 2279–2289 (1994)
24. Tsitlanadze, G., Kviria, T., Katsarava, R., Chu, C.C.: Biodegradation of amino acid based poly(ester amide)s: in vitro study using potentiometric titration. J. Mater. Sci.: Mater. Med. 15, 185–190 (2004)
25. Gomurashvili, Z., Kricheldorf, H.R., Katsarava, R.: Amino acid based bioanalogous polymers. synthesis and study of new poly(ester amide)s composed of hydrophobic a-amino acids and dianhydrohexitoles. J. Macromol. Sci. Pure Appl. Chem. A37, 215–227 (2000)
26. Guo, K., Chu, C.C., Chkhaidze, E., Katsarava, R.: Synthesis and characterization of novel biodegradable unsaturated poly(ester-amide)s. Polym. Sci. A 43, 1463–1477 (2005)
27. Perez-Rodriguez, A., Alla, A., Fernandez-Santin, J.M., Munoz-Guerra, S.: Poly(ester amide)s derived from tartaric and succinic acids: changes in structure and properties upon hydrolytic degradation. J. Appl. Polym. Sci. 78, 486–494 (2000)
28. Li, X., Lu, X., Lin, Y., Zhan, J., Li, Y., Liu, Z., Chen, X., Liu, S.: Synthesis and characterization of hyperbranched poly(ester-amide)s from commercially available dicarboxylic acids and multihydroxyl primary amines. Macromolecules 39, 7889–7899 (2006)
29. Li, X., Su, Y., Chen, Q., Lin, Y., Tong, Y., Li, Y.: Synthesis and Characterization of Biodegradable Hyperbranched Poly(ester-amide)s Based on Natural Material. Biomacromolecules 6, 3181–3188 (2005)
30. Katsarava, R.: Active polycondensation–from peptide chemistry to amino acid based biodegradable polymers. Macromol. Symp. 199, 419–429 (2003)
31. Vera, M., Puiggal, A., Coudane, J.: Microspheres from new biodegradable poly(ester amide)s with different ratios of L-and D-alanine for controlled drug delivery. J. Microencap. 23(6), 686–697 (2006)
32. Legashvili, I., Nepharidze, N., Katsarava, R., Sannigrahi, B., Khan, I.: Non-covalent nano-adducts of co-poly(ester amide) and poly(ethylene glycol): preparation, characterization and model drugrelease studies. J. Biomater. Sci. Polym. Ed. 18, 673–685 (2007)
33. Lin, Y., Zhang, K.Y., Dong, Z.-M., Dong, L.S., Li, Y.: Study of hydrogen-bonded blend of polylactide with biodegradable hyperbranched poly(ester amide). Macromolecules 40, 6257–6267 (2007)
34. Lin, Y., Liu, X., Dong, Z., Li, B., Chen, X., Li, Y.: Amphiphilic Core-Shell Nanocarriers Based On Hyperbranched Poly(ester amide)-star-PCL: Synthesis, Characterization, and Potential as Efficient Phase Transfer Agent. Biomacromolecules 9, 2629–2636 (2008)