Vertebrate attenuated West Nile virus mutants have differing effects on vector competence in Culex tarsalis mosquitoes

Journal of General Virology

Volumn 94, Issue PART 5, 2013, Pages 1069-1072

  Van Slyke, Greta A ^a   Jia, Yongqing ^a   Whiteman, Melissa C ^b   Wicker, Jason A ^b,d   Barrett, Alan D T ^b   Kramer, Laura D ^a,c  

^a WADSWORTH CENTER   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

^c STATE UNIVERSITY OF NEW YORK   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENVELOPE PROTEIN; NONSTRUCTURAL PROTEIN 1; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 4B; NONSTRUCTURAL PROTEIN 5A;

AMINO ACID SUBSTITUTION; ARTICLE; BIRD; CULEX; CULEX TARSALIS; GLYCOSYLATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; TEMPERATURE; VIRUS GENOME; VIRUS TRANSMISSION; WEST NILE FLAVIVIRUS;

EID: 84876216620     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.049833-0     Document Type: Article

References (21)

1. Beasley, D. W., Whiteman, M. C., Zhang, S., Huang, C. Y., Schneider, B. S., Smith, D. R., Gromowski, G. D., Higgs, S., Kinney, R. M. & Barrett, A. D. (2005). Envelope protein glycosylation status influences mouse neuroinvasion phenotype of genetic lineage 1 West Nile virus strains. J Virol 79, 8339-8347.
2. Brault, A. C., Langevin, S. A., Ramey, W. N., Fang, Y., Beasley, D. W., Barker, C. M., Sanders, T. A., Reisen, W. K., Barrett, A. D. & Bowen, R. A. (2011). Reduced avian virulence and viremia of West Nile virus isolates from Mexico and Texas. Am J Trop Med Hyg 85, 758-767.
3. Davis, C. T., Beasley, D. W., Guzman, H., Siirin, M., Parsons, R. E., Tesh, R. B. & Barrett, A. D. (2004). Emergence of attenuated West Nile virus variants in Texas, 2003. Virology 330, 342-350.
4. Davis, C. T., Ebel, G. D., Lanciotti, R. S., Brault, A. C., Guzman, H., Siirin, M., Lambert, A., Parsons, R. E., Beasley, D. W. & other authors (2005). Phylogenetic analysis of North American West Nile virus isolates, 2001-2004: evidence for the emergence of a dominant genotype. Virology 342, 252-265.
5. Dupuis, A. P., II, Marra, P. P. & Kramer, L. D. (2003). Serologic evidence of West Nile virus transmission, Jamaica, West Indies. Emerg Infect Dis 9, 860-863.
6. Ebel, G. D., Rochlin, I., Longacker, J. & Kramer, L. D. (2005). Culex restuans (Diptera: Culicidae) relative abundance and vector competence for West Nile Virus. J Med Entomol 42, 838-843.
7. Lanciotti, R. S., Roehrig, J. T., Deubel, V., Smith, J., Parker, M., Steele, K., Crise, B., Volpe, K. E., Crabtree, M. B. & other authors (1999). Origin of the West Nile virus responsible for an outbreak of encephalitis in the northeastern United States. Science 286, 2333-2337.
8. Langevin, S. A., Bowen, R. A., Ramey, W. N., Sanders, T. A., Maharaj, P. D., Fang, Y., Cornelius, J., Barker, C. M., Reisen, W. K. & other authors (2011). Envelope and pre-membrane protein structural amino acid mutations mediate diminished avian growth and virulence of a Mexican West Nile virus isolate. J Gen Virol 92, 2810-2820.
9. May, F. J., Li, L., Davis, C. T., Galbraith, S. E. & Barrett, A. D. (2010). Multiple pathways to the attenuation of West Nile virus in south-east Texas in 2003. Virology 405, 8-14.
10. Molaei, G., Andreadis, T. G., Armstrong, P. M., Anderson, J. F. & Vossbrinck, C. R. (2006). Host feeding patterns of Culex mosquitoes and West Nile virus transmission, northeastern United States. Emerg Infect Dis 12, 468-474.
11. Moudy, R. M., Meola, M. A., Morin, L. L., Ebel, G. D. & Kramer, L. D. (2007). A newly emergent genotype of West Nile virus is transmitted earlier and more efficiently by Culex mosquitoes. Am J Trop Med Hyg 77, 365-370.
12. Moudy, R. M., Zhang, B., Shi, P. Y. & Kramer, L. D. (2009). West Nile virus envelope protein glycosylation is required for efficient viral transmission by Culex vectors. Virology 387, 222-228.
13. Murata, R., Eshita, Y., Maeda, A., Maeda, J., Akita, S., Tanaka, T., Yoshii, K., Kariwa, H., Umemura, T. & Takashima, I. (2010). Glycosylation of the West Nile virus envelope protein increases in vivo and in vitro viral multiplication in birds. Am J Trop Med Hyg 82, 696-704.
14. Puig-Basagoiti, F., Tilgner, M., Bennett, C. J., Zhou, Y., Muñoz- Jordán, J. L., García-Sastre, A., Bernard, K. A. & Shi, P. Y. (2007). A mouse cell-adapted NS4B mutation attenuates West Nile virus RNA synthesis. Virology 361, 229-241.
15. Thiemann, T. C., Wheeler, S. S., Barker, C. M. & Reisen, W. K. (2011). Mosquito host selection varies seasonally with host availability and mosquito density. PLoS Negl Trop Dis 5, e1452.
16. Totani, M., Yoshii, K., Kariwa, H. & Takashima, I. (2011). Glycosylation of the envelope protein of West Nile virus affects its replication in chicks. Avian Dis 55, 561-568.
17. Turell, M. J., Dohm, D. J., Sardelis, M. R., Oguinn, M. L., Andreadis, T. G. & Blow, J. A. (2005). An update on the potential of north American mosquitoes (Diptera: Culicidae) to transmit West Nile virus. J Med Entomol 42, 57-62.
18. Welte, T., Xie, G., Wicker, J. A., Whiteman, M. C., Li, L., Rachamallu, A., Barrett, A. & Wang, T. (2011). Immune responses to an attenuated West Nile virus NS4B-P38G mutant strain. Vaccine 29, 4853-4861.
19. Whiteman, M. C., Li, L., Wicker, J. A., Kinney, R. M., Huang, C., Beasley, D. W., Chung, K. M., Diamond, M. S., Solomon, T. & Barrett, A. D. (2010). Development and characterization of non-glycosylated E and NS1 mutant viruses as a potential candidate vaccine for West Nile virus. Vaccine 28, 1075-1083.
20. Whiteman, M. C., Wicker, J. A., Kinney, R. M., Huang, C. Y., Solomon, T. & Barrett, A. D. (2011). Multiple amino acid changes at the first glycosylation motif NS1 protein of WNV are necessary for complete attenuation for mouse neuroinvasiveness. Vaccine 29, 9702-9710.
21. Wicker, J. A., Whiteman, M. C., Beasley, D. W., Davis, C. T., Zhang, S., Schneider, B. S., Higgs, S., Kinney, R. M. & Barrett, A. D. (2006). A single amino acid substitution in the central portion of the West Nile virus NS4B protein confers a highly attenuated phenotype in mice. Virology 349, 245-253.