Tough times for medicinal chemists: Are we to blame?

ACS Medicinal Chemistry Letters

Volumn 4, Issue 4, 2013, Pages 369-370

  Tsukamoto, Takashi ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAM; G PROTEIN COUPLED RECEPTOR; PENICILLIN BINDING PROTEIN;

CHEMISTRY; DRUG APPROVAL; DRUG FORMULATION; DRUG INDUSTRY; PRIORITY JOURNAL; SHORT SURVEY;

EID: 84876207061     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml400074k     Document Type: Short Survey

References (5)

1. Walters, W. P.; Green, J.; Weiss, J. R.; Murcko, M. A. What do medicinal chemists actually make? A 50-year retrospective J. Med. Chem. 2011, 54, 6405-16
2. Eric, S. Lander Nat. Rev. Drug Discovery 2004, 3, 730-730
3. Lowe, D. B. Nowhere To Go But Up: The Return of Medicinal Chemistry ACS Med. Chem. Lett. 2012, 3, 3-4
4. Hert, J.; Irwin, J. J.; Laggner, C.; Keiser, M. J.; Shoichet, B. K. Quantifying biogenic bias in screening libraries Nat. Chem. Biol. 2009, 5, 479-83
5. Bauer, R. A.; Wurst, J. M.; Tan, D. S. Expanding the range of 'druggable' targets with natural product-based libraries: an academic perspective Curr. Opin. Chem. Biol. 2010, 14, 308-14