Clot resolution after 3 weeks of anticoagulant treatment for pulmonary embolism: Comparison of computed tomography and perfusion scintigraphy

Journal of Thrombosis and Haemostasis

Volumn 11, Issue 4, 2013, Pages 679-685

  Van Es, J ^a   Douma, R A ^a   Kamphuisen, P W ^b   Gerdes, V E A ^a,c   Verhamme, P ^d   Wells, P S ^e   Bounameaux, H ^f   Lensing, A W A ^g   Buller H R ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c SLOTERVAART HOSPITAL   (Netherlands)

^d UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^e UNIVERSITY OF OTTAWA   (Canada)

^f GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^g BAYER PHARMA AG   (Germany)

Author keywords

Anticoagulant therapy; Clot resolution; CT scan; Perfusion scintigraphy; Pulmonary embolism

Indexed keywords

ANTIVITAMIN K; ENOXAPARIN; RIVAROXABAN;

ACUTE PULMONARY EMBOLISM; ADULT; ANTICOAGULANT THERAPY; ARTICLE; BLOOD CLOT; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; CONTROLLED STUDY; DRUG DOSE INCREASE; FEMALE; HUMAN; LUNG EMBOLISM; LUNG SCINTISCANNING; MAJOR CLINICAL STUDY; MALE; OPEN STUDY; PRIORITY JOURNAL; PULMONARY ARTERY OCCLUSION; RANDOMIZED CONTROLLED TRIAL;

ADULT; AGED; ANTICOAGULANTS; FEMALE; HUMANS; MALE; MIDDLE AGED; PERFUSION IMAGING; PULMONARY EMBOLISM; THROMBOSIS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84876196402     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/jth.12150     Document Type: Article

References (14)

1. Nijkeuter M, Hovens MM, Davidson BL, Huisman MV. Resolution of thromboemboli in patients with acute pulmonary embolism: a systematic review. Chest 2006; 129: 192-7.
2. Donadini MP, Dentali F, Cosmi B, Bozzato S, Neri C, Squizzato A, Venco A, Ageno W. Presence of residual thromboemboli at least six months after a first episode of symptomatic pulmonary embolism: do perfusion scintigraphy and angio-computed tomography agree? Thromb Haemost 2009; 102: 1287-9.
3. Buller HR, Prins MH, Lensing AW, Decousus H, Jacobson BF, Minar E, Chlumsky J, Verhamme P, Wells P, Agnelli G, Cohen A, Berkowitz SD, Bounameaux H, Davidson BL, Misselwitz F, Gallus AS, Raskob GE, Schellong S, Segers A. Oral rivaroxaban for the treatment of symptomatic pulmonary embolism. N Engl J Med 2012; 366: 1287-97.
4. Agnelli G, Gallus A, Goldhaber SZ, Haas S, Huisman MV, Hull RD, Kakkar AK, Misselwitz F, Schellong S. Treatment of proximal deep vein thrombosis with the oral direct factor Xa inhibitor rivaroxaban (BAY 59-7939): the ODIXa-DVT (Oral Direct Factor Xa Inhibitor BAY 59-7939 in Patients With Acute Symptomatic Deep Vein Thrombosis) study. Circulation 2007; 116: 180-7.
5. Buller HR, Lensing AW, Prins MH, Agnelli G, Cohen A, Gallus AS, Misselwitz F, Raskob G, Schellong S, Segers A. A dose-ranging study evaluating once-daily oral administration of the factor Xa inhibitor rivaroxaban in the treatment of patients with acute symptomatic deep vein thrombosis: the Einstein-DVT Dose-Ranging Study. Blood 2008; 112: 2242-7.
6. Wittram C. How I do it: CT pulmonary angiography. AJr. Am J Roentgenol 2007; 188: 1255-61.
7. Parker JA, Coleman RE, Grady E, Royal HD, Siegel BA, Stabin MG, Sostman HD, Hilson AJ. SNM practice guideline for lung scintigraphy 4.0. J Nucl Med Technol 2012; 40: 57-65.
8. Meyer G, Collignon MA, Guinet F, Jeffrey AA, Barritault L, Sors H. Comparison of perfusion lung scanning and angiography in the estimation of vascular obstruction in acute pulmonary embolism. Eur J Nucl Med 1990; 17: 315-19.
9. Wartski M, Collignon MA. Incomplete recovery of lung perfusion after 3 months in patients with acute pulmonary embolism treated with antithrombotic agents. THESEE Study Group. Tinzaparin ou Heparin Standard: Evaluation dans l'Embolie Pulmonaire Study. J Nucl Med 2000; 41: 1043-8.
10. Hvid-Jacobsen K, Fogh J, Nielsen SL, Thomsen HS, Hartling OJ. Scintigraphic control of pulmonary embolism. Eur J Nucl Med 1988; 14: 71-2.
11. PIOPED. Value of the ventilation/perfusion scan in acute pulmonary embolism. Results of the prospective investigation of pulmonary embolism diagnosis (PIOPED). The PIOPED Investigators. JAMA 1990; 263: 2753-9.
12. van Rossum AB, Pattynama PM, Tjin AT, Kieft GJ. Spiral CT appearance of resolving clots at 6 week follow-up after acute pulmonary embolism. J Comput Assist Tomogr 1998; 22: 413-17.
13. Cosmi B, Nijkeuter M, Valentino M, Huisman MV, Barozzi L, Palareti G. Residual emboli on lung perfusion scan or multidetector computed tomography after a first episode of acute pulmonary embolism. Intern Emerg Med 2011; 6: 521-8.
14. Remy-Jardin M, Louvegny S, Remy J, Artaud D, Deschildre F, Bauchart JJ, Thery C, Duhamel A. Acute central thromboembolic disease: posttherapeutic follow-up with spiral CT angiography. Radiology 1997; 203: 173-80.