Comment concerning the role of cd47 and signal regulatory protein alpha in regulating the clearance of aged red blood cells

Transfusion Medicine and Hemotherapy

Volumn 40, Issue 2, 2013, Pages 140-141

  Lutz, Hans U ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CD47 ANTIGEN; ERYTHROCYTE BAND 3 PROTEIN; REGULATOR PROTEIN; SIGNAL REGULATORY PROTEIN ALPHA; THROMBOSPONDIN 1; UNCLASSIFIED DRUG;

CELL AGING; CELL ISOLATION; CLEARANCE; COMPLEMENT ALTERNATIVE PATHWAY; CONFORMATIONAL TRANSITION; CYTOSKELETON; ERYTHROCYTE; ERYTHROPHAGOCYTOSIS; HUMAN; LETTER; MACROPHAGE; NONHUMAN; OPSONIZATION; PROTEIN PHOSPHORYLATION;

EID: 84876174402     PISSN: 16603796     EISSN: 16603818     Source Type: Journal    
DOI: 10.1159/000350507     Document Type: Letter

References (17)

1. Oldenborg PA, Zheleznyak A, Fang YF, Lagenaur CF, Gresham HD, Lindberg FP: Role of CD47 as a marker of self on red blood cells. Science 2000; 288:2051-2054.
2. Oldenborg PA, Gresham HD, Lindberg FP: CD47-signal regulatory protein alpha (SIRP alpha) regulates Fc gamma and complement receptor-mediated phagocytosis. J Exp Med 2001;193:855-861.
3. Burger P, Hilarius-Stokman P, de Korte D, van den Berg TK, van Bruggen R: CD47 functions as a molecular switch for erythrocyte phagocytosis. Blood 2012;119:5512-5521.
4. Burger P, de Korte D, van den Berg TK, van Bruggen R: CD47 in erythrocyte ageing and clearancethe Dutch point of view. Transfus Med Hemother 2012;39:348-352.
5. Gao AG, Lindberg FP, Finn MB, Blystone SD, Brown EJ, Frazier WA: Integrin-Associated protein is a receptor for the C-terminal domain of thrombospondin. J Biol Chem 1996;271:21-24.
6. Novelli EM, Kato GJ, Ragni MV, Zhang Y, Hildesheim ME, Nouraie M, Barge S, Meyer MP, Hassett AC, Gordeuk VR, Gladwin MT, Isenberg JS: Plasma thrombospondin-1 is increased during acute sickle cell vaso-occlusive events and associated with acute chest syndrome, hydroxyurea therapy, and lower hemolytic rates. Am J Hematol 2012;87:326-330.
7. Head DJ, Lee ZE, Swallah MM, Avent ND: Ligation of CD47 mediates phosphatidylserine expression on erythrocytes and a concomitant loss of viability in vitro. Br J Haematol 2005;130:788-790.
8. Subramanian S, Tsai R, Sen S, Dahl KN, Discher DE: Membrane mobility and clustering of Integrin Associated Protein (IAP, CD47)-major differences between mouse and man and implications for signaling. Blood Cells Mol Dis 2006;36:364-372.
9. Lutz HU: Naturally occurring anti-band 3 antibodies in clearance of senescent and oxidatively stressed human red blood cells. Transfus Med Hemother 2012;39:321-327.
10. Lutz HU, Flepp R, Stringaro-Wipf G: Naturally occurring autoantibodies to exoplasmic and cryptic regions of band 3 protein, the major integral membrane protein of human red blood cells. J Immunol 1984;133:2610-2618.
11. Schweizer E, Angst W, Lutz HU: Glycoprotein topology on intact human red blood cells reevaluated by cross-linking following amino-group supplementation. Biochemistry 1982;21:6807-6818.
12. Ferru E, Giger K, Pantaleo A, Campanella E, Grey J, Ritchie K, Vono R, Turrini F, Low PS: Regulation of membrane-cytoskeletal interactions by tyrosine phosphorylation of erythrocyte band 3. Blood 2011;117:5998-6006.
13. Pantaleo A, Giribaldi G, Mannu F, Arese P, Turrini F: Naturally occurring anti-band 3 antibodies and red blood cell removal under physiological and pathological conditions. Autoimmun Rev 2008;7: 457-462.
14. Lutz HU, Bussolino F, Flepp R, Fasler S, Stammler P, Kazatchkine MD, Arese P: Naturally occurring anti-band 3 antibodies and complement together mediate phagocytosis of oxidatively stressed human red blood cells. Proc Natl Acad Sci U S A 1987;84:7368-7372.
15. Lutz HU, Nater M, Stammler P: Naturally occurring anti-band 3 antibodies have a unique affinity for C3. Immunology 1993;80:191-196.
16. Lutz HU, Stammler P, Fasler S: Preferential formation of C3b-IgG complexes in vitro and in vivo from nascent C3b and naturally occurring antiband antibodies. J Biol Chem 1993;268:17418-17426.
17. Jelezarova E, Vogt A, Lutz HU: Interaction of C3b2-IgG complexes with complement proteins properdin, factor B and factor H: implications for amplification. Biochem J 2000;349:217-223.