Clinical significance of h-TERT and c-Met expression in the peripheral blood circulation of pancreatic cancer patients

Chinese Journal of Clinical Oncology

Volumn 40, Issue 4, 2013, Pages 208-211

  Hu, Liang ^a   Zhou, Jiahua ^b   Yu, Zeqian ^b   Yi, Yongxiang ^a   Ding, Hai ^a   Zhao, Liang ^a  

^a Nanjing Second Hospital   (China)

^b AFFILIATED ZHONGDA HOSPITAL OF SOUTHEAST UNIVERSITY   (China)

Author keywords

C Met; H TERT; Micrometastasis; Pancreatic cancer

Indexed keywords

CA 19-9 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; SCATTER FACTOR RECEPTOR; TELOMERASE REVERSE TRANSCRIPTASE;

AGE; ARTICLE; CANCER PATIENT; CANCER PROGNOSIS; CANCER RECURRENCE; CANCER SIZE; CANCER STAGING; CELL SELECTION; DISEASE FREE SURVIVAL; GENDER; GENE EXPRESSION; HUMAN; HUMAN TISSUE; MICROMETASTASIS; PANCREAS CANCER; PERIPHERAL CIRCULATION; PROTEIN BLOOD LEVEL; RECURRENCE RISK; SURVIVAL TIME;

EID: 84876152143     PISSN: 10008179     EISSN: None     Source Type: Journal    
DOI: 10.3969/j.issn.1000-8179.2013.04.007     Document Type: Article

References (14)

1. Yekebas EF, Bogoevski D, Bubenheim M, et al. Strong prognostic value of nodal and bone marrow micro-involvement in patients with pancreatic ductal carcinoma receiving no adjuvant chemotherapy[J]. WorldJ Gastroenterol, 2006, 12(40):6515-6521. (Pubitemid 44742587)
2. Zhao L, Mou DC, Peng JR, et al. Diagnostic value of cancer-testis antigen mRNA in peripheral blood from hepatocellular carcinoma patients[J]. WorldJ Gastroenterol, 2010, 16( 32) : 4072-4078.
3. Muto Y, Matubara H, Tanizawa T, et al. Rapid diagnosis of micrometastasis of gastric cancer using reverse transcription loop-mediated isothermal amplification[J]. Oncol Rep, 2011, 26( 4): 789-794.
4. Paterlini-Brechot P, Benali NL. Circulating tumour cells (CTC) detection: clinical impact and future directions[J]. Cancer Lett, 2007, 253(2):180-204. (Pubitemid 47017533)
5. Kumari A, Srinivasan R, Vasishta RK, et al. Positive regulation of human telomerase reverse transcriptase gene expression and telomerase activity by DNA methylation in pancreatic cancer[J]. Ann Surg Oncol, 2009, 16( 4): 1051-1059.
6. Zhou J, Hu L, Yu Z, et al. Marker expression in circulating cancer cells of pancreatic cancer patients.[J]. J Surg Res, 2011, 171( 2): 631-636.
7. Antoniou KM, Margaritopoulos GA, Proklou A, et al. Investigation of telomerase/telomeres system in bone marrow mesenchymal stem cells derived from IPF and RA-UIP[J] J Inflamm (Lond), 2012, 9( 1) : 27.
8. Grochola LF, Greither T, Taubert HW, et al. Prognostic relevance of hTERT mRNA expression in ductal adenocarcinoma of the pancreas[J]. Neoplasia, 2008, 10( 9): 973-976.
9. Lee JH, Khadka P, Baek SH, et al. CHIP promotes human telomerase reverse transcriptase degradation and negatively regulates telomerase activity[J]. J Biol Chem, 2010, 285( 53): 42033-42045.
10. Chrysovergis A, Gorgoulis VG, Giotakis I, et al. Simultaneous over activation of EGFR, telomerase (h-TERT), and cyclin Dl correlates with advanced disease in larynx squamous cell carcinoma: a tissue microarray analysis[J]. Med Oncol, 2011, 28( 3): 871-877.
11. Miyamoto M, Ojima H, Iwasaki M, et al. Prognostic significance of overexpression of c-Met oncoprotein in cholangiocarcinoma[J]. Br J Cancer, 2011, 105( 1): 131-138.
12. Oh YM, Song YJ, Lee SB, et al. A new anti-c-met antibody selected by a mechanism-based dual-screening method: therapeutic potential in cancer[J]. MoI Cells, 2012, 34( 6): 523-529.
13. Herreros-Villanueva M, Zubia-Olascoaga A, Bujanda L. c-Met in pancreatic cancer stem cells: therapeutic implications[J]. World J Gastroenterol, 2012, 18( 38) : 5321-5323.
14. Gardian K, Janczewska S, Olszewski WL, et al. Analysis of pancreatic cancer microenvironment: role of macrophage infiltrates and growth factors expression[J]. J Cancer, 2012, 3: 285-291.