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Volumn 36, Issue 10, 2013, Pages 1379-1390

Active flow management in chromatographic separations: A preliminary investigation into enhanced preparative scale separation using a parallel segmented outlet flow distributor

Author keywords

bed heterogeneity; end column detection; local detection; preparative HPLC; purification; segmented flow chromatography

Indexed keywords

BED HETEROGENEITY; CHROMATOGRAPHIC SEPARATIONS; COLUMN HETEROGENEITY; MOBILE-PHASE VELOCITY; PERIPHERAL REGIONS; PREPARATIVE HPLC; PREPARATIVE SCALE SEPARATIONS; SEGMENTED FLOW;

EID: 84876150253     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826076.2012.691438     Document Type: Article
Times cited : (6)

References (26)
  • 2
    • 0001267802 scopus 로고
    • Interaction of radial and axial dispersion in liquid chromatography in relation to the "infinite diameter effect"
    • Knox, J. H.; Laird, G. R.; Raven, P. A. Interaction of Radial and Axial Dispersion in Liquid Chromatography in Relation to the "Infinite Diameter Effect". J. Chromatogr. A 1976, 122, 129-145.
    • (1976) J. Chromatogr. A , vol.122 , pp. 129-145
    • Knox, J.H.1    Laird, G.R.2    Raven, P.A.3
  • 3
    • 0034604836 scopus 로고    scopus 로고
    • Physical evidence of two wall effects in liquid chromatography
    • Shalliker, R. A.; Broyles, B. S.; Guiochon, G. Physical Evidence of Two Wall Effects in Liquid Chromatography. J. Chromatogr. A 2000, 888, 1-12.
    • (2000) J. Chromatogr. A , vol.888 , pp. 1-12
    • Shalliker, R.A.1    Broyles, B.S.2    Guiochon, G.3
  • 4
    • 0037159482 scopus 로고    scopus 로고
    • Visualization of bed compression in an axial compression liquid chromatography column
    • Shalliker, R. A.; Wong, V.; Broyles, B. S.; Guiochon, G. Visualization of Bed Compression in an Axial Compression Liquid Chromatography Column. J. Chromatogr. A 2002, 977, 213-223.
    • (2002) J. Chromatogr. A , vol.977 , pp. 213-223
    • Shalliker, R.A.1    Wong, V.2    Broyles, B.S.3    Guiochon, G.4
  • 5
    • 0038667519 scopus 로고    scopus 로고
    • Axial and radial diffusion coefficients in a liquid chromatography column and bed heterogeneity
    • Shalliker, R. A.; Broyles, B. S.; Guiochon, G. Axial and Radial Diffusion Coefficients in a Liquid Chromatography Column and Bed Heterogeneity. J. Chromatogr. A 2003, 994, 1-12.
    • (2003) J. Chromatogr. A , vol.994 , pp. 1-12
    • Shalliker, R.A.1    Broyles, B.S.2    Guiochon, G.3
  • 6
  • 8
    • 0028321961 scopus 로고
    • Modeling of radial heterogeneity in chromatographic columns columns with cylindrical symmetry and ideal model
    • Yun, T.; Guiochon, G. Modeling of Radial Heterogeneity in Chromatographic Columns Columns with Cylindrical Symmetry and Ideal Model. J. Chromatogr. A 1994, 672, 1-10.
    • (1994) J. Chromatogr. A , vol.672 , pp. 1-10
    • Yun, T.1    Guiochon, G.2
  • 9
    • 0037332470 scopus 로고    scopus 로고
    • Mechanics of column beds: I. acquisition of the relevant parameters
    • Yew, B. G.; Drumm, E. C.; Guiochon, G. Mechanics of Column Beds: I. Acquisition of the Relevant Parameters. AIChE J. 2003, 49, 626-641.
    • (2003) AIChE J. , vol.49 , pp. 626-641
    • Yew, B.G.1    Drumm, E.C.2    Guiochon, G.3
  • 10
    • 0032953718 scopus 로고    scopus 로고
    • Estimation of the column radial heterogeneity from an analysis of the characteristics of tailing peaks in linear chromatography
    • Miyabe, K.; Guiochon, G. Estimation of the Column Radial Heterogeneity from an Analysis of the Characteristics of Tailing Peaks in Linear Chromatography. J. Chromatogr. A 1999, 830, 29-39.
    • (1999) J. Chromatogr. A , vol.830 , pp. 29-39
    • Miyabe, K.1    Guiochon, G.2
  • 11
    • 0031208458 scopus 로고    scopus 로고
    • Radial distribution of the flow velocity, efficiency and concentration in a wide HPLC column
    • Farkas, T.; Sepaniak, M. J.; Guiochon, G. Radial Distribution of the Flow Velocity, Efficiency and Concentration in a Wide HPLC Column. AIChE J. 1997, 43, 1964-1974.
    • (1997) AIChE J. , vol.43 , pp. 1964-1974
    • Farkas, T.1    Sepaniak, M.J.2    Guiochon, G.3
  • 12
    • 0028031297 scopus 로고
    • Column efficiency and radial homogeneity in liquid chromatography
    • Farkas, T.; Chambers, Q. J.; Guiochon, G. Column Efficiency and Radial Homogeneity in Liquid Chromatography. J. Chromatogr. A 1994, 679, 231-245.
    • (1994) J. Chromatogr. A , vol.679 , pp. 231-245
    • Farkas, T.1    Chambers, Q.J.2    Guiochon, G.3
  • 13
    • 62249120318 scopus 로고    scopus 로고
    • Radial heterogeneity of some analytical columns used in high-performance liquid chromatography
    • Abia, J. A.; Mriziq, K. S.; Guiochon, G. A. Radial Heterogeneity of Some Analytical Columns Used in High-Performance Liquid Chromatography. J. Chromatogr. A 2009, 1216, 3185-3191.
    • (2009) J. Chromatogr. A , vol.1216 , pp. 3185-3191
    • Abia, J.A.1    Mriziq, K.S.2    Guiochon, G.A.3
  • 14
    • 0030295321 scopus 로고    scopus 로고
    • Measurement of transverse and axial apparent dispersion coefficients in packed beds
    • Tallarek, U.; Albert, K.; Bayer, E.; Guiochon, G. Measurement of Transverse and Axial Apparent Dispersion Coefficients in Packed Beds. AIChE J. 1996, 42, 3041-3054.
    • (1996) AIChE J. , vol.42 , pp. 3041-3054
    • Tallarek, U.1    Albert, K.2    Bayer, E.3    Guiochon, G.4
  • 15
    • 0001689755 scopus 로고
    • A comparison of mobile-phase peak dispersion in gas and liquid chromatography
    • Horne, D. S.; Knox, J. H.; McLaren, L. A Comparison of Mobile-Phase Peak Dispersion in Gas and Liquid Chromatography. Sep. Sci. Technol. 1966, 1, 531-554.
    • (1966) Sep. Sci. Technol. , vol.1 , pp. 531-554
    • Horne, D.S.1    Knox, J.H.2    McLaren, L.3
  • 16
    • 0032564857 scopus 로고    scopus 로고
    • Study of dispersion in packed chromatographic columns by pulsed field gradient nuclear magnetic resonance
    • Tallarek, U.; Bayer, E.; Guiochon, G. Study of Dispersion in Packed Chromatographic Columns by Pulsed Field Gradient Nuclear Magnetic Resonance. J. Am. Chem. Soc. 1998, 120, 1494-1505.
    • (1998) J. Am. Chem. Soc. , vol.120 , pp. 1494-1505
    • Tallarek, U.1    Bayer, E.2    Guiochon, G.3
  • 17
    • 0002580461 scopus 로고
    • Comparison of broadening patterns in regular and radially compressed large-diameter columns
    • Eon, C. H. Comparison of Broadening Patterns in Regular and Radially Compressed Large-Diameter Columns. J. Chromatogr. A 1978, 149, 29-42.
    • (1978) J. Chromatogr. A , vol.149 , pp. 29-42
    • Eon, C.H.1
  • 18
    • 0024116125 scopus 로고
    • Radial dispersion from commercial high-performance liquid chromatography columns investigated with microvoltammetric electrodes
    • Baur, J. E.; Kristensen, E. W.; Wightman, R. M. Radial Dispersion from Commercial High-Performance Liquid Chromatography Columns Investigated with Microvoltammetric Electrodes. Anal. Chem. 1988, 60, 2334-2338.
    • (1988) Anal. Chem. , vol.60 , pp. 2334-2338
    • Baur, J.E.1    Kristensen, E.W.2    Wightman, R.M.3
  • 19
    • 0003107531 scopus 로고
    • Microcylinder electrodes as sensitive detectors for high-efficiency, high-speed liquid chromatography
    • Baur, J. E., Wightman, R. M. Microcylinder Electrodes as Sensitive Detectors for High-Efficiency, High-Speed Liquid Chromatography. J. Chromatogr. A 1989, 482, 65-73.
    • (1989) J. Chromatogr. A , vol.482 , pp. 65-73
    • Baur, J.E.1    Wightman, R.M.2
  • 20
    • 0000061850 scopus 로고    scopus 로고
    • Contribution of the radial distribution of the flow velocity to band broadening in HPLC columns
    • Farkas, T.; Guiochon, G. Contribution of the Radial Distribution of the Flow Velocity to Band Broadening in HPLC Columns. Anal. Chem. 1997, 69, 4592-4600.
    • (1997) Anal. Chem. , vol.69 , pp. 4592-4600
    • Farkas, T.1    Guiochon, G.2
  • 21
    • 0034650531 scopus 로고    scopus 로고
    • On-column visualization of sample migration in liquid chromatography
    • Shalliker, R. A.; Broyles, B. S.; Guiochon, G. On-Column Visualization of Sample Migration in Liquid Chromatography. Anal. Chem. 1999, 72, 323-332.
    • (1999) Anal. Chem. , vol.72 , pp. 323-332
    • Shalliker, R.A.1    Broyles, B.S.2    Guiochon, G.3
  • 22
    • 0035844077 scopus 로고    scopus 로고
    • Visualization of solute migration in chromatographic columns: Influence of the frit porosity
    • Broyles, B. S.; Shalliker, R. A.; Guiochon, G. Visualization of Solute Migration in Chromatographic Columns: Influence of the Frit Porosity. J. Chromatogr. A, 2001, 917, 1-22.
    • (2001) J. Chromatogr. A , vol.917 , pp. 1-22
    • Broyles, B.S.1    Shalliker, R.A.2    Guiochon, G.3
  • 23
    • 0032877259 scopus 로고    scopus 로고
    • Visualization of sample introduction in liquid chromatography columns: The effect of the frit diameter
    • Broyles, B. S.; Shalliker, R. A.; Guiochon, G. Visualization of Sample Introduction in Liquid Chromatography Columns: The Effect of the Frit Diameter. J. Chromatogr. A 1999, 855, 367-382.
    • (1999) J. Chromatogr. A , vol.855 , pp. 367-382
    • Broyles, B.S.1    Shalliker, R.A.2    Guiochon, G.3
  • 24
    • 0032728521 scopus 로고    scopus 로고
    • Visualization of sample introduction in liquid chromatographic columns: Contribution of a flow distributor on the sample band shape
    • Shalliker, R. A.; Broyles, B. S.; Guiochon, G. Visualization of Sample Introduction in Liquid Chromatographic Columns: Contribution of a Flow Distributor on the Sample Band Shape. J. Chromatogr. A 1999, 865, 83-95.
    • (1999) J. Chromatogr. A , vol.865 , pp. 83-95
    • Shalliker, R.A.1    Broyles, B.S.2    Guiochon, G.3
  • 25
    • 33846633195 scopus 로고    scopus 로고
    • Visualising viscous fingering in chromatography columns: High viscosity solute plug
    • Shalliker, R. A.; Catchpoole, H. J.; Dennis, G. R.; Guiochon, G. Visualising Viscous Fingering in Chromatography Columns: High Viscosity Solute Plug. J. Chromatogr. A 2007, 1142, 48-55.
    • (2007) J. Chromatogr. A , vol.1142 , pp. 48-55
    • Shalliker, R.A.1    Catchpoole, H.J.2    Dennis, G.R.3    Guiochon, G.4
  • 26
    • 33646422245 scopus 로고    scopus 로고
    • Visualising the onset of viscous fingering in chromatography columns
    • Catchpoole, H. J.; Shalliker, R. A.; Dennis, G. R.; Guiochon, G. Visualising the Onset of Viscous Fingering in Chromatography Columns. J. Chromatogr. A 2006, 1117, 137-145.
    • (2006) J. Chromatogr. A , vol.1117 , pp. 137-145
    • Catchpoole, H.J.1    Shalliker, R.A.2    Dennis, G.R.3    Guiochon, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.