메뉴 건너뛰기




Volumn 3, Issue NOV, 2012, Pages

The role of CTCF binding sites in the 3′ immunoglobulin heavy chain regulatory region

Author keywords

Chromosome conformation capture (3C) assay; Class switch recombination; CTCF; Enhancers; Immunoglobulin heavy chain gene locus; Insulators; Pax5

Indexed keywords

MAMMALIA;

EID: 84876149034     PISSN: None     EISSN: 16648021     Source Type: Journal    
DOI: 10.3389/fgene.2012.00251     Document Type: Review
Times cited : (19)

References (45)
  • 1
    • 78650351488 scopus 로고    scopus 로고
    • Gene insulation Part II: natural strategies in vertebrates
    • Amouyal, M. (2010). Gene insulation. Part II: natural strategies in vertebrates. Biochem. Cell. Biol. 88, 885-898.
    • (2010) Biochem. Cell. Biol. , vol.88 , pp. 885-898
    • Amouyal, M.1
  • 2
    • 77951625010 scopus 로고    scopus 로고
    • vivo redundant function of the 3′ IgH regulatory element HS3b in the mouse
    • Bebin, A. G., Carrion, C., Marquet, M., Cogne, N., Lecardeur, S., Cogne, M., et al. (2010). In vivo redundant function of the 3′ IgH regulatory element HS3b in the mouse. J. Immunol. 184, 3710-3717.
    • (2010) J. Immunol. , vol.184 , pp. 3710-3717
    • Bebin, A.G.1    Carrion, C.2    Marquet, M.3    Cogne, N.4    Lecardeur, S.5    Cogne, M.6
  • 3
    • 0025982149 scopus 로고
    • DNA sequences 3′ of the IgH chain cluster rearrange in mouse B cell lines
    • Calvo, C.-F., Giannini, S. L., Martinez, N., and Birshtein, B. K. (1991). DNA sequences 3′ of the IgH chain cluster rearrange in mouse B cell lines. J. Immunol. 146, 1353-1360.
    • (1991) J. Immunol. , vol.146 , pp. 1353-1360
    • Calvo, C.-F.1    Giannini, S.L.2    Martinez, N.3    Birshtein, B.K.4
  • 4
    • 80051688660 scopus 로고    scopus 로고
    • Dynamic changes in binding of immunoglobulin heavy chain 3′ regulatory region to protein factors during class switching
    • Chatterjee, S., Ju, Z., Hassan, R., Volpi, S. A., Emelyanov, A. V., and Birshtein, B. K. (2011). Dynamic changes in binding of immunoglobulin heavy chain 3′ regulatory region to protein factors during class switching. J. Biol. Chem. 286,29303-29312.
    • (2011) J. Biol. Chem. , vol.286 , pp. 29303-29312
    • Chatterjee, S.1    Ju, Z.2    Hassan, R.3    Volpi, S.A.4    Emelyanov, A.V.5    Birshtein, B.K.6
  • 6
    • 0031201186 scopus 로고    scopus 로고
    • Virtually identical enhancers containing a segment of homology to murine 3′IgH-E(hsl 2) lie downstream of human Ig C alpha 1 and C alpha 2 genes
    • Chen, C., and Birshtein, B. K. (1997). Virtually identical enhancers containing a segment of homology to murine 3′IgH-E(hsl,2) lie downstream of human Ig C alpha 1 and C alpha 2 genes. J. Immunol. 159, 1310-1318.
    • (1997) J. Immunol. , vol.159 , pp. 1310-1318
    • Chen, C.1    Birshtein, B.K.2
  • 8
    • 84941639029 scopus 로고    scopus 로고
    • Regulation of class switch recombination
    • eds. T. Honjo, E W. Alt and M. Neuberger (San Diego CA: Elsevier Academic Press)
    • Cogne, M., and Birshtein, B. K. (2004). Regulation of class switch recombination, in Molecular Biology of B Cells, eds. T. Honjo, E W. Alt and M. Neuberger (San Diego, CA: Elsevier Academic Press), 289-305.
    • (2004) Molecular Biology of B Cells , pp. 289-305
    • Cogne, M.1    Birshtein, B.K.2
  • 9
    • 0028233142 scopus 로고
    • A class switch control region at the 3′ end of the immunoglobulin heavy chain locus
    • Cogne, M., Lansford, R., Bottaro, A., Zhang, J., Gorman, J., Young, F., et al. (1994). A class switch control region at the 3′ end of the immunoglobulin heavy chain locus. Cell 77, 737-747.
    • (1994) Cell , vol.77 , pp. 737-747
    • Cogne, M.1    Lansford, R.2    Bottaro, A.3    Zhang, J.4    Gorman, J.5    Young, F.6
  • 10
    • 79959354832 scopus 로고    scopus 로고
    • CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells
    • Degner, S. C., Verma-Gaur, J., Wong, T. P., Bossen, C., Iverson, G. M., Torkamani,A.,et al. (2011). CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells. Proc. Natl. Acad. Sci. U.S.A. 108, 9566-9571.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 9566-9571
    • Degner, S.C.1    Verma-Gaur, J.2    Wong, T.P.3    Bossen, C.4    Iverson, G.M.5    Torkamani, A.6
  • 11
    • 59849122478 scopus 로고    scopus 로고
    • Cutting edge: developmental stage-specific recruitment of cohesin to CTCF sites throughout immunoglobulin loci during B lymphocyte development
    • Degner, S. C., Wong, T. P., Jankevicius, G., and Feeney, A. J. (2009). Cutting edge: developmental stage-specific recruitment of cohesin to CTCF sites throughout immunoglobulin loci during B lymphocyte development. J. Immunol. 182, 44-48.
    • (2009) J. Immunol. , vol.182 , pp. 44-48
    • Degner, S.C.1    Wong, T.P.2    Jankevicius, G.3    Feeney, A.J.4
  • 12
    • 80555126080 scopus 로고    scopus 로고
    • Enhancement of antibody class-switch recombination by the cumulative activity of four separate elements
    • Dunnick, W A., Shi, J., Zerbato, J. M., Fontaine, C. A., and Collins, J. T. (2011). Enhancement of antibody class-switch recombination by the cumulative activity of four separate elements. J. Immunol. 187, 4733-4743.
    • (2011) J. Immunol. , vol.187 , pp. 4733-4743
    • Dunnick, W.A.1    Shi, J.2    Zerbato, J.M.3    Fontaine, C.A.4    Collins, J.T.5
  • 13
    • 0033104977 scopus 로고    scopus 로고
    • Evidence that a single replication fork proceeds from early to late replicating domains in the IgH locus in a non-B cell line
    • Ermakova, O. V., Nguyen, L. H., Little, R. D., Chevillard, C., Riblet, R., Ashouian, N., et al. (1999). Evidence that a single replication fork proceeds from early to late replicating domains in the IgH locus in a non-B cell line. Mol. Cell 3,321-330.
    • (1999) Mol. Cell , vol.3 , pp. 321-330
    • Ermakova, O.V.1    Nguyen, L.H.2    Little, R.D.3    Chevillard, C.4    Riblet, R.5    Ashouian, N.6
  • 14
    • 62649145611 scopus 로고    scopus 로고
    • Allelic frequencies of 3′ Ig heavy chain locus enhancer HS1, 2-A associated with Ig levels in patients with schizophrenia.
    • Frezza, D., Giambra, V., Mattioli, C., Piccoli, K., Massoud, R., Siracusano, A., et al. (2009). Allelic frequencies of 3′ Ig heavy chain locus enhancer HS1,2-A associated with Ig levels in patients with schizophrenia. Int. J. Immunopathol. Pharmacol. 22, 115-123.
    • (2009) Int. J. Immunopathol. Pharmacol. , vol.22 , pp. 115-123
    • Frezza, D.1    Giambra, V.2    Mattioli, C.3    Piccoli, K.4    Massoud, R.5    Siracusano, A.6
  • 15
    • 13444270605 scopus 로고    scopus 로고
    • Chromatin architecture near a potential 3′ end of the igh locus involves modular regulation of histone modifications during B-Cell development and in vivo occupancy at CTCF sites
    • Garrett, F. E., Emelyanov, A. V., Sepulveda, M. A., Flanagan, P., Volpi, S., Li,E, et al. (2005). Chromatin architecture near a potential 3′ end of the igh locus involves modular regulation of histone modifications during B-Cell development and in vivo occupancy at CTCF sites. Mol. Cell. Biol. 25, 1511-1525.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 1511-1525
    • Garrett, F.E.1    Emelyanov, A.V.2    Sepulveda, M.A.3    Flanagan, P.4    Volpi, S.5    Li, E.6
  • 16
    • 52649138951 scopus 로고    scopus 로고
    • Pax5 and linker histone H1 coordinate DNA methylation and histone modifications in the 3′ regulatory region of the immunoglobulin heavy chain locus
    • Giambra, V., Volpi, S., Emelyanov, A. V., Pflugh, D., Bothwell, A. L., Norio, P., et al. (2008). Pax5 and linker histone H1 coordinate DNA methylation and histone modifications in the 3′ regulatory region of the immunoglobulin heavy chain locus. Mol. Cell. Biol. 28, 6123-6133.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 6123-6133
    • Giambra, V.1    Volpi, S.2    Emelyanov, A.V.3    Pflugh, D.4    Bothwell, A.L.5    Norio, P.6
  • 17
    • 0027173505 scopus 로고
    • DNA regions flanking the mouse Ig 3′a enhancer are differentially methylated and DNAse I hypersensitive during B cell differentiation
    • Giannini, S. L., Singh, M., Calvo, C.-E, Ding, G., and Birshtein, B. K. (1993). DNA regions flanking the mouse Ig 3′a enhancer are differentially methylated and DNAse I hypersensitive during B cell differentiation. J. Immunol. 150, 1772-1780.
    • (1993) J. Immunol. , vol.150 , pp. 1772-1780
    • Giannini, S.L.1    Singh, M.2    Calvo, C.-E.3    Ding, G.4    Birshtein, B.K.5
  • 18
    • 0037514314 scopus 로고    scopus 로고
    • Yin Yang 1 is a lipopolysaccharide-inducible activator of the murine 3′ Igh enhancer, hs3
    • Gordon, S. J., Saleque, S., and Birshtein, B. K. (2003). Yin Yang 1 is a lipopolysaccharide-inducible activator of the murine 3′ Igh enhancer, hs3. J. Immunol. 170, 5549-5557.
    • (2003) J. Immunol. , vol.170 , pp. 5549-5557
    • Gordon, S.J.1    Saleque, S.2    Birshtein, B.K.3
  • 19
    • 0022730593 scopus 로고
    • Myelomamutantwithanovel 3′ flanking region: loss of normal sequence and insertion of repetitive elements leads to decreased transcription but normal processing of the alpha heavy-chain gene products
    • Gregor, P. D., and Morrison, S. L. (1986).Myelomamutantwithanovel 3′ flanking region: loss of normal sequence and insertion of repetitive elements leads to decreased transcription but normal processing of the alpha heavy-chain gene products. Mol. Cell. Biol. 6,1903-1916.
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 1903-1916
    • Gregor, P.D.1    Morrison, S.L.2
  • 20
    • 80053130223 scopus 로고    scopus 로고
    • CTCF-binding elements mediate control of V(D) J recombination
    • Guo, C., Yoon, H. S., Franklin, A., Jain, S., Ebert, A., Cheng, H. L., et al. (2011). CTCF-binding elements mediate control of V(D) J recombination. Nature 477, 424-430.
    • (2011) Nature , vol.477 , pp. 424-430
    • Guo, C.1    Yoon, H.S.2    Franklin, A.3    Jain, S.4    Ebert, A.5    Cheng, H.L.6
  • 21
    • 82455220324 scopus 로고    scopus 로고
    • Interaction between the immunoglobulin heavy chain 3′ regulatory region and the IgH transcription unit during B cell differentiation
    • Ju, Z., Chatterjee, S., and Birshtein, B. K. (2011). Interaction between the immunoglobulin heavy chain 3′ regulatory region and the IgH transcription unit during B cell differentiation. Mol. Immunol. 49, 297-303.
    • (2011) Mol. Immunol. , vol.49 , pp. 297-303
    • Ju, Z.1    Chatterjee, S.2    Birshtein, B.K.3
  • 22
    • 36849020399 scopus 로고    scopus 로고
    • Evidence for physical interaction between the immunoglobulin heavy chain variable region and the 3′ regulatory region
    • Ju, Z., Volpi, S. A., Hassan, R., Martinez, N., Giannini, S. L., Gold, T., et al. (2007). Evidence for physical interaction between the immunoglobulin heavy chain variable region and the 3′ regulatory region. J. Biol. Chem. 282, 35169-35178.
    • (2007) J. Biol. Chem. , vol.282 , pp. 35169-35178
    • Ju, Z.1    Volpi, S.A.2    Hassan, R.3    Martinez, N.4    Giannini, S.L.5    Gold, T.6
  • 23
    • 0032547798 scopus 로고    scopus 로고
    • Class switching in B cells lacking 3′ immunoglobulin heavy chain enhancers
    • Manis, J. P., Van Der Stoep, N., Tian, M., Ferrini, R., Davidson, L., Bottaro, A., et al. (1998). Class switching in B cells lacking 3′ immunoglobulin heavy chain enhancers. J. Exp. Med. 188,1421-1431.
    • (1998) J. Exp. Med. , vol.188 , pp. 1421-1431
    • Manis, J.P.1    Van Der Stoep, N.2    Tian, M.3    Ferrini, R.4    Davidson, L.5    Bottaro, A.6
  • 24
    • 67349262410 scopus 로고    scopus 로고
    • Immunoglobulins: molecular genetics
    • Chap. 6. (ed. ) W. E. Paul (Philadelphia: Wolters Kluwer/Lippincott Williams &Wilkins)
    • Max, E. E. (2008). Immunoglobulins: molecular genetics, in Fundamental Immunology, Chap. 6. (ed.) W. E. Paul (Philadelphia: Wolters Kluwer/Lippincott Williams &Wilkins), 192-236.
    • (2008) Fundamental Immunology , pp. 192-236
    • Max, E.E.1
  • 25
    • 0030840416 scopus 로고    scopus 로고
    • Regulation of the replication of the murine immunoglobulin heavy chain gene locus: evaluation of the role of the 3′ regulatory region
    • Michaelson, J. S., Ermakova, O., Birshtein, B. K., Ashouian, N., Chevillard, C., Riblet, R., et al. (1997). Regulation of the replication of the murine immunoglobulin heavy chain gene locus: evaluation of the role of the 3′ regulatory region. Mol. Cell. Biol. 17, 6167-6174.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 6167-6174
    • Michaelson, J.S.1    Ermakova, O.2    Birshtein, B.K.3    Ashouian, N.4    Chevillard, C.5    Riblet, R.6
  • 26
    • 0028988293 scopus 로고
    • Identification of 3′ alpha-hs4, a novel Ig heavy chain enhancer element regulated at multiple stages of B cell differentiation
    • Michaelson, J. S., Giannini, S. L., and Birshtein, B. K. (1995). Identification of 3′ alpha-hs4, a novel Ig heavy chain enhancer element regulated at multiple stages of B cell differentiation. Nucleic Acids Res. 23, 975-981.
    • (1995) Nucleic Acids Res , vol.23 , pp. 975-981
    • Michaelson, J.S.1    Giannini, S.L.2    Birshtein, B.K.3
  • 27
    • 0030584725 scopus 로고    scopus 로고
    • Regulation of 3′ IgH enhancers by a common set of factors, including kappa B-binding proteins
    • Michaelson, J. S., Singh, M., Snapper, C. M., Sha, W C, Baltimore, D., and Birshtein, B. K. (1996). Regulation of 3′ IgH enhancers by a common set of factors, including kappa B-binding proteins. J. Immunol. 156, 2828-2839.
    • (1996) J. Immunol. , vol.156 , pp. 2828-2839
    • Michaelson, J.S.1    Singh, M.2    Snapper, C.M.3    Sha, W.C.4    Baltimore, D.5    Birshtein, B.K.6
  • 28
    • 0030886813 scopus 로고    scopus 로고
    • Enhancer complexes located downstream of both human immunoglobulin C alpha genes
    • Mills, F. C., Harindranath, N., Mitchell, M., and Max, E. E. (1997). Enhancer complexes located downstream of both human immunoglobulin C alpha genes. J. Exp. Med. 186, 845-858.
    • (1997) J. Exp. Med. , vol.186 , pp. 845-858
    • Mills, F.C.1    Harindranath, N.2    Mitchell, M.3    Max, E.E.4
  • 29
    • 67549119096 scopus 로고    scopus 로고
    • CTCF: master weaver of the genome
    • Phillips, J. E., and Corces, V. G. (2009). CTCF: master weaver of the genome. Cell 137, 1194-1211.
    • (2009) Cell , vol.137 , pp. 1194-1211
    • Phillips, J.E.1    Corces, V.G.2
  • 31
    • 0033104687 scopus 로고    scopus 로고
    • Ig heavy chain expression and class switching in vitro from an allele lacking the 3′ enhancers DNase I-hypersensitive hs3A and hs1
    • Saleque, S., Singh, M., and Birshtein, B. K. (1999). Ig heavy chain expression and class switching in vitro from an allele lacking the 3′ enhancers DNase I-hypersensitive hs3A and hs1,2. J. Immunol. 162,2791-2803.
    • (1999) 2. J. Immunol. , vol.162 , pp. 2791-2803
    • Saleque, S.1    Singh, M.2    Birshtein, B.K.3
  • 32
    • 0031569966 scopus 로고    scopus 로고
    • Dyad symmetry within the mouse 3′ IgH regulatory region includes two virtually identical enhancers (C alpha3′E and hs3)
    • Saleque, S., Singh, M., Little, R. D., Giannini, S. L., Michaelson, J. S., and Birshtein, B. K. (1997). Dyad symmetry within the mouse 3′ IgH regulatory region includes two virtually identical enhancers (C alpha3′E and hs3). J. Immunol. 158,4780-4787.
    • (1997) J. Immunol. , vol.158 , pp. 4780-4787
    • Saleque, S.1    Singh, M.2    Little, R.D.3    Giannini, S.L.4    Michaelson, J.S.5    Birshtein, B.K.6
  • 33
    • 1642536443 scopus 로고    scopus 로고
    • NF-kappaB and Oct-2 synergize to activate the human 3′ Igh hs4 enhancer in B cells
    • Sepulveda, M. A., Emelyanov, A. V., and Birshtein, B. K. (2004a). NF-kappaB and Oct-2 synergize to activate the human 3′ Igh hs4 enhancer in B cells. J. Immunol. 172, 1054-1064.
    • (2004) J. Immunol. , vol.172 , pp. 1054-1064
    • Sepulveda, M.A.1    Emelyanov, A.V.2    Birshtein, B.K.3
  • 34
    • 10844228012 scopus 로고    scopus 로고
    • Comparative analysis of human and mouse 3′ Igh regulatory regions identifies distinctive structural features
    • Sepulveda, M. A., Garrett, F. E., Price-Whelan, A., and Birshtein, B. K. (2004b). Comparative analysis of human and mouse 3′ Igh regulatory regions identifies distinctive structural features. Mol. Immunol. 42, 605-615.
    • (2004) Mol. Immunol. , vol.42 , pp. 605-615
    • Sepulveda, M.A.1    Garrett, F.E.2    Price-Whelan, A.3    Birshtein, B.K.4
  • 35
    • 0027316156 scopus 로고
    • NF-HB (BSAP) is a repressor of the murine immunoglobulin heavy-chain 3′ alpha enhancer at early stages of B-cell differentiation
    • Singh, M., and Birshtein, B. K. (1993). NF-HB (BSAP) is a repressor of the murine immunoglobulin heavy-chain 3′ alpha enhancer at early stages of B-cell differentiation. Mol Cell. Biol. 13,3611-3622.
    • (1993) Mol Cell. Biol. , vol.13 , pp. 3611-3622
    • Singh, M.1    Birshtein, B.K.2
  • 36
    • 0029989292 scopus 로고    scopus 로고
    • Concerted repression of an immunoglobulin heavy-chain enhancer, 3′ alpha E(hs1 2)
    • Singh, M., and Birshtein, B. K. (1996). Concerted repression of an immunoglobulin heavy-chain enhancer, 3′ alpha E(hs1,2). Proc. Natl.Acad. Sci. U.S.A. 93,4392-4397.
    • (1996) Proc. Natl.Acad. Sci. U.S.A. , vol.93 , pp. 4392-4397
    • Singh, M.1    Birshtein, B.K.2
  • 37
    • 77956899151 scopus 로고    scopus 로고
    • Genomic deletion of the whole IgH 3′ regulatory region (hs3a, hs1,2, hs3b, hs4) dramatically affects class switch recombination and Ig secretion to all isotypes
    • Vincent-Fabert, C., Fiancette, R., Pinaud, E., Truffinet, V., Cogne, N., Cogne, M., et al. (2010). Genomic deletion of the whole IgH 3′ regulatory region (hs3a, hs1,2, hs3b, hs4) dramatically affects class switch recombination and Ig secretion to all isotypes. Blood 116, 1895-1898.
    • (2010) Blood , vol.116 , pp. 1895-1898
    • Vincent-Fabert, C.1    Fiancette, R.2    Pinaud, E.3    Truffinet, V.4    Cogne, N.5    Cogne, M.6
  • 38
    • 67449113516 scopus 로고    scopus 로고
    • Ig synthesis and class switching do not require the presence of the hs4 enhancer in the 3′ IgH regulatory region
    • Vincent-Fabert, C., Truffinet, V., Fiancette, R., Cogne, N., Cogne, M., and Denizot, Y. (2009). Ig synthesis and class switching do not require the presence of the hs4 enhancer in the 3′ IgH regulatory region. J. Immunol. 182,6926-6932.
    • (2009) J. Immunol. , vol.182 , pp. 6926-6932
    • Vincent-Fabert, C.1    Truffinet, V.2    Fiancette, R.3    Cogne, N.4    Cogne, M.5    Denizot, Y.6
  • 39
    • 84857812660 scopus 로고    scopus 로고
    • Germline deletion of Igh 3′ regulatory region elements hs 5, 6, 7 (hs5-7) affects B cell-specific regulation, rearrangement, and insulation of the Igh locus
    • Volpi, S. A., Verma-Gaur, J., Hassan, R., Ju, Z., Roa, S., Chatterjee, S., et al. (2012). Germline deletion of Igh 3′ regulatory region elements hs 5, 6, 7 (hs5-7) affects B cell-specific regulation, rearrangement, and insulation of the Igh locus. J. Immunol. 188, 2556-2566.
    • (2012) J. Immunol. , vol.188 , pp. 2556-2566
    • Volpi, S.A.1    Verma-Gaur, J.2    Hassan, R.3    Ju, Z.4    Roa, S.5    Chatterjee, S.6
  • 40
    • 36148940618 scopus 로고    scopus 로고
    • S-S synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deam-inase
    • Wuerffel, R., Wang, L., Grigera, F., Manis, J., Selsing, E., Perlot, T., et al. (2007). S-S synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deam-inase. Immunity 22,711-722.
    • (2007) Immunity , vol.22 , pp. 711-722
    • Wuerffel, R.1    Wang, L.2    Grigera, F.3    Manis, J.4    Selsing, E.5    Perlot, T.6
  • 41
    • 79961002783 scopus 로고    scopus 로고
    • Homologous elements hs3a and hs3b in the 3′ regulatory region of the murine immunoglobulin heavy chain (Igh) locus are both dispensable for class-switch recombination
    • Yan, Y., Pieretti, J., Ju, Z., Wei, S., Christin, J. R., Bah, F., et al. (2011). Homologous elements hs3a and hs3b in the 3′ regulatory region of the murine immunoglobulin heavy chain (Igh) locus are both dispensable for class-switch recombination. J. Biol. Chem. 286, 27123-27131.
    • (2011) J. Biol. Chem. , vol.286 , pp. 27123-27131
    • Yan, Y.1    Pieretti, J.2    Ju, Z.3    Wei, S.4    Christin, J.R.5    Bah, F.6
  • 42
    • 79959448657 scopus 로고    scopus 로고
    • Chromatin insulators: a role in nuclear organization and gene expression
    • Yang, J., and Corces, V G. (2011). Chromatin insulators: a role in nuclear organization and gene expression. Adv. Cancer Res. 110,43-76.
    • (2011) Adv. Cancer Res. , vol.110 , pp. 43-76
    • Yang, J.1    Corces, V.G.2
  • 43
    • 0037108950 scopus 로고    scopus 로고
    • The origin of a developmentally regulated Igh replicon is located near the border of regulatory domains for Igh replication and expression
    • Zhou, J., Ashouian, N., Delepine, M., Matsuda, F., Chevillard, C., Riblet, R., et al. (2002a). The origin of a developmentally regulated Igh replicon is located near the border of regulatory domains for Igh replication and expression. Proc. Natl. Acad. Sci. U.S.A. 99, 13693-13698.
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 13693-13698
    • Zhou, J.1    Ashouian, N.2    Delepine, M.3    Matsuda, F.4    Chevillard, C.5    Riblet, R.6
  • 44
    • 0036274021 scopus 로고    scopus 로고
    • Replication and subnuclear location dynamics of the immunoglobulin heavy-chain locus in B-lineage cells
    • Zhou, J., Ermakova, O. V., Riblet, R., Birshtein, B. K., and Schildkraut, C. L. (2002b). Replication and subnuclear location dynamics of the immunoglobulin heavy-chain locus in B-lineage cells. Mol. Cell. Biol. 22, 4876-4889.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 4876-4889
    • Zhou, J.1    Ermakova, O.V.2    Riblet, R.3    Birshtein, B.K.4    Schildkraut, C.L.5
  • 45
    • 23444441496 scopus 로고    scopus 로고
    • Changes in replication, nuclear location, and expression of the Igh locus after fusion of a pre-B cell line with a T cell line
    • Zhou, J., Saleque, S., Ermakova, O., Sepulveda, M. A., Yang, Q., Eckhardt, L. A., et al. (2005). Changes in replication, nuclear location, and expression of the Igh locus after fusion of a pre-B cell line with a T cell line. J. Immunol. 175,2317-2320.
    • (2005) J. Immunol , vol.175 , pp. 2317-2320
    • Zhou, J.1    Saleque, S.2    Ermakova, O.3    Sepulveda, M.A.4    Yang, Q.5    Eckhardt, L.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.